Structure of PDB 8brm Chain LI Binding Site BS01

Receptor Information
>8brm Chain LI (length=187) Species: 184922 (Giardia lamblia ATCC 50803) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LTPFVRWPRQVRIQRQKAVLQRRLKVPPTVNQFMNPISRNLTNEIFNLAR
KYSPESKEEHKARLLQIADAKAKSDKLVIASGIRRITSLVESKRAKLVLI
ANDVDPLELVLWLPTLCHKMGVPYAIVRTKGDLGKLVHLKKTTSVCFTDV
NPEDKPTFDKILAAVAHEVDYAKAMKTYGGGVRREDE
Ligand information
>8brm Chain LD (length=142) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcacgccccgccggcggaugccucggcccgggcggcgacgaagagcgcgg
cggagcgcgagacgcggugcggacccgcccgccccgagaagcaccgaucc
ucgaacgcagcgcgccccggcgccgccgccucggcgccugcc
..........................................<<<<<<.(
(.....>>>.....<<<<<<...<..))..>.........>>>>>>...>
>>....<<...>><<<..>>>.....................
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8brm Insights into translocation mechanism and ribosome evolution from cryo-EM structures of translocation intermediates of Giardia intestinalis.
Resolution3.33 Å
Binding residue
(original residue number in PDB)		Q41 R42 R66 N136 D137 R162 T163
Binding residue
(residue number reindexed from 1)		Q14 R15 R39 N102 D103 R128 T129
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0000470 maturation of LSU-rRNA
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8brm, PDBe:8brm, PDBj:8brm
PDBsum8brm
PubMed36912103
UniProtA8BLL7

[Back to BioLiP]