Structure of PDB 9fq0 Chain LE Binding Site BS01

Receptor Information
>9fq0 Chain LE (length=214) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PHCSRNPVLVRGIGRYSRSAMYSRKAMYKRKYLATVTKPVGGDKNGGTRV
VKLRKMPRYYPTEDVPRKLLSHGKKPFSQHVRKLRASITPGTILIILTGR
HRGKRVVFLKQLASGLLLVTGPLVLNRVPLRRTHQKFVIATSTKIDISNV
KIPKHLTDAYFKKKKYEITEQRKIDQKAVDSQILPKIKAIPQLQGYLRSV
FALTNGIYPHKLVF
Ligand information
>9fq0 Chain 1 (length=298) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
caaguccuucugaucgaggcccagcccguggacggugugaggccgguagu
ugaaaagaacuuugaagagagaguucaagagggcgccgcccggaggauuc
aacccggcggcggguccggccgugucggcggcccggcggaucuuucccgc
gcgggggaccgucccccgaccggcgaccggccgccgccgggcgcauuucc
accgcggcgguucaaacgagaacuuugaaucggguucagauccccgaauc
uuggaaagcgucgcgguuccggcggcguaagggcugggcagccgacuu
<....<<<<......>>>>.....((......<<<.....))>>>...>.
.........<<<<....>>>>...............<<<<<<<.<<<...
..<<<<<<<<<<<..<<<<<<<.......<.....<<<<.<<<..<<...
...>>>>>>>>>.>......>>>>...>>>>>>>>>>>>>>......>>>
.>>>.>>>>.<<<<<<.......>>>>>><<<<<........>>>>>...
.......<<<<<<<.......>>>>>>><<<<<<<<..>>>>>..>>>
Receptor-Ligand Complex Structure
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PDB9fq0 Multi-protein assemblies orchestrate enzymatic processing of the nascent chain on the 80S ribosome
Resolution4.67 Å
Binding residue
(original residue number in PDB)		K94 P95 V96 G97 G98 K100 N101 R105 V107 R110 P113 R114 Y115
Binding residue
(residue number reindexed from 1)		K38 P39 V40 G41 G42 K44 N45 R49 V51 R54 P57 R58 Y59
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0045296 cadherin binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0002181 cytoplasmic translation
GO:0006355 regulation of DNA-templated transcription
GO:0006412 translation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005791 rough endoplasmic reticulum
GO:0005829 cytosol
GO:0005840 ribosome
GO:0005925 focal adhesion
GO:0014069 postsynaptic density
GO:0016020 membrane
GO:0022625 cytosolic large ribosomal subunit
GO:0022626 cytosolic ribosome
GO:0036464 cytoplasmic ribonucleoprotein granule
GO:0045202 synapse
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:9fq0, PDBe:9fq0, PDBj:9fq0
PDBsum9fq0
PubMed
UniProtQ02878|RL6_HUMAN Large ribosomal subunit protein eL6 (Gene Name=RPL6)

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