Structure of PDB 7old Chain LB Binding Site BS01 |
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| >7old Chain 1 (length=3192)
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guugaccucggaucagguaggaggacccgcugaacuuaagcauaucaaua
agcggaggaaaagaaaccaacagggauugcccuaguaacggcgagugaag
cggcaacagcucaaauuugaaagcuggcuucggcccgcguuguaauuugg
agaggaugcuuugggcgaggcuccuucugaguucccuggaacgggacgcc
acagagggugagagccccguauaguuggaagccaagccuguguaaagcuc
cuucgacgagucgaguaguuugggaaugcugcucaaaaugggagguaaau
uucuucuaaagcuaaauaccggccagagaccgauagcgcacaaguagagu
gaucgaaagaugaaaagcacuuugaaaagaggguuaaauagcacgugaaa
uuguugaaagggaagcgcuugugaccagacuugcgcccggcggaucaucc
gguguucucaccggugcacuccgccgggcucaggccagcaucgguucugg
cggggggauaaaggcccagggaauguggcuccuccgggaguguuauagcc
cuggguguaauacccucgccgggaccgaggaccgcgcucugcaaggaugc
uggcguaauggucaccagcgacccgucuugaaacacggaccaaggaguca
agguuuugcgcgaguguuuggguguaaaacccgcacgcguaaugaaagug
aacguaggugagagcuucggcgcaucaucgaccgauccugauguauucgg
auggauuugaguaggagcguuaagccuuggacccgaaagauggugaacua
ugcuuggauagggugaagccagaggaaacucugguggaggcucgcagcgg
uucugacgugcaaaucgaucgucaaaucugagcaugggggcgaaagacua
aucgaaccaucuaguagcugguuaccgccgaaguuucccucaggauagca
gugucgaccuucaguuuuaugagguaaagcgaaugauuagggacucgggg
gcgauuuuuagccuucauccauucucaaacuuuaaauauguaagaagccc
uuguuacuuaacugaacgugggcauucgaauguaucgacacuagugggcc
auuuuugguaagcagaacuggcgaugcgggaugaaccgaacgcgggguua
aggugccggaguggacgcucaucagacaccacaaaaggcguuaguacauc
uugacagcaggacgguggccauggaagucggaauccgcuaaggacugugu
aacaacucaccugccgaauguacuagcccugaaaauggauggcgcucaag
cgucccacccauaccccgcccucaggguagaaacgaugcccugaggagua
ggcggccguggaggucagugacgaagccuagggcgugagcccgggucgaa
cggccucuagugcagaucuuggugguaguagcaaauacuucaaugagaac
uugaaggaccgaaguggggaaagguuccaugugaacagcgguuggacaug
gguuagucgauccuaagccauagggaaguuccguuucaaaggggcacucg
ugccccguguggcgaaagggaagccgguuaauauuccggcaccuggaugu
ggguuuugcgcggcaacgcaacugaacgcggagacgacggcgggggcccc
gggcagaguucucuuuucuucuuaacggucuaucacccuggaaacaguuu
gucuggagauaggguuuaauggccggaagagcccgacacuucugucgggu
ccggugcgcucucgacgucccuugaaaauccgcgggagggaauaauucuc
acgccaggucguacucauaaccgcagcagguccccaaggugaacagccuc
ugguugauagaacaauguagauaagggaagucggcaaaauagauccguaa
cuucgggaaaaggauuggcucuaaggguugggcacguuggcggcgugcgg
uuaacaaccaacuuagaacugguacggacagggggaaucugacugucuaa
uuaaaacauagcauugcgauggccagaaagugguguugacgcaaugugau
uucugcccagugcucugaaugucaaagugaagaaauucaaccaagcgcgg
guaaacggcgggaguaacuaugacucucuuaagguagccaaaugccucgu
caucuaauuagugacgcgcaugaauggauuaacgagauucccacuguccc
uaucuacuaucuagcgaaaccacagccaagggaacgggcuuggcaaaauc
agcggggaaagaagacccuguugagcuugacucuaguuugacauugugaa
aagacauaggagcuccuauuguuuuuuuacuuauucaaugaagcggggcu
ggacuugcguccaacuucuggaguuaagguccuucgcgggccgacccggg
uugaagacauugucagguggggaguuuggcuggggcggcacaucuguuaa
accauaacgcagguguccuaaggggggcucauggagaacagaaaucucca
guagaacaaaaggguaaaaguccccuugauuuugauuuucagugugaaua
caaaccaugaaaguguggccuaucgauccuuuagucccucgaaauuugag
gcuagaggugccagaaaaguuaccacagggauaacuggcuuguggcggcc
aagcguucauagcgacgucgcuuuuugauccuucgaugucggcucuuccu
aucauaccgaagcagaauucgguaagcguuggauuguucacccacuaaua
gggaacgugagcuggguuuagaccgucgugagacagguuaguuuuacccu
acugaugaacucgucgcaaugguaauucagcuuaguacgagaggaaccgc
ugauucagauaauugguuuuugcgguuguccgaccgggcagugccgcgaa
gcuaccaucugcuggauaauggcugaacgccucuaagucagaauccaugc
cagaacgcgacgauacuacccgcacguuguagacguauaagaauaggcuc
cggccucguauccuagcaggcgauuccuccgccggccucgaaguggccgu
cgguaauucgcguauugcaauuuagacacgcgcgggaucaaauccuuugc
agacgacuuagaugugcgaaaggguccuguaagcaguagaguagccuugu
uguuacgaucugcugaggguaagcccuccuucgccuagauuu |
.........................<<<<<<.....<......>......
>>>>>.>.........<<....>>..<<<<<......<<.....>>....
.>>>>>..[[[..<<.......<<.<<<<..>>>>.>>.......>>...
.<<<<<.<<<<<<<<<..<<<<<<........<<<<......>>>>.((.
.....<<<.....))>>>........>>.>>>>..>>>>....>>>>>>>
>.>>........<<<<<<<........>>>>>>>.....(((((..<<<<
<<)))))..]]]..................................<<..
..>>...............<<<<....>>>>...................
...............<<<<.<<<<<<.....<<.<<<<<<<<<.....<<
<<<<....>>>>>>......>>>>>>>>>.>>.<<<<<<<.<<<<<<<<<
<<<<<<.....<.<<<<<<<<......<<<<<....>>>>>.......>>
>>>>>>....>.>>>>>>>>>>>>>>>........<<...>>.....>>>
>>>>.....>>>>>>.>>>>..<<<<........>>>><<<<<<....<<
<<<<<<.<<<<..<<<...<<<<.....>>>>...>>>...<<....>>.
......<<<<<..<<<..>>>...>>>>>.<<<<<<<<...<<....>>.
..>>>.>>>.>>....>>>>.>>>>>>>>..<<.<...<<<<<<.....<
<<<<<<<<..<<<....<<<<<<<....>>>>>>>.....>>>...<<<.
.<<.<<........>>>>.>>>....>>>>>>>>>...<<.......>>.
.....>>>>>>......>.>>...<<<<<....<.<<<....>>>.><<<
<<<<<<.....<<.<<<<<<<.....<<<....<<<..<.<<<...<<<<
<<........>>>>>>.>>>.>..>>>..>>.>.....>>>>>...<<<<
.<<<<.<......>>>>>.>>>>.....>>>>...>>>>>>>.>>..<<<
<.<<<<<.....>>>>>.>>>>....<<<......>>>...<<<<<<<..
.<<<(((.....<<<<<<.....<<..........<<<.<<<<<<<<<<.
......<<<<<.<<<...<<.........>>...>>>.........<<..
....>>...>>>>>...>>>>>>>>>>>>>..........))).>>...>
>>>>>.>>>...>>>>>>><<<<<<<<<.........>>>>>>>>>....
>>>>>.<.<<<<<<<<.<<......<<<<.<<<<....>>>>>>>>...>
>>>>>>>>>..>.....>>>>>><<.....<<.....<<<<<<.......
>>>>>><<<<.....<<<<<.<<...<<<<<....<<.....>>..>>>>
>....((<<<<<<...<<<...<<<....>>>........<<<<<.....
.>>>>>....>>>....>>...<<<<<........>>>>>))<<<<.<<<
<.<<<....<<<....>>>.......<<<<<<...<<<<.<<<<<<<.<<
<<<.<<<<.......>>>>.><...<<<<<....<<<<<<....<<<...
..>>>....>>>>>>.....>>>>>....><<<<<<<......>>>>>>>
>>>>...>>>>>>>.>>>>.........>>>>>>.........>>>...>
>>>>>>>>>>>..>>.....<<......>>>>>>>.<<<<.....>>>>.
.>>>>..<<<<.....<<<<<<<.<<.........<.....<<<<<....
<<..>>.....>>>>><<.<<<<<<<<<<<.......<....>.......
....>>>>>..>>>>>>.>>............<<<<<<<<<..<<<....
.....>>>..<<<<<<<....<<<<.....>>>>......>>>>>>>...
<<..<<<..<<<<<<....<<<.....<<<<....>>>>.....>>>.>>
>>..>>>>><<<<<<.......>>>>>>........<...........<<
<<<.......>>>>>.....>.....>>....>>.>>>>>>>..>..>>.
>>>>>>>..>>>>>>....>>....<<<<<........>>>>>....[[[
[[..{{{.{{......[[[[.{{[[[[..<<<<<.<<<<<<<<..<<<<<
<<<<<<<<<<<..>>>>>.>>>>>>>>>>>...<<<<<.....<<<<..<
<<<<....>>>>>..............<<<<<.....>>>>>..>>>>..
>>>>>.....>>>>>>>>..>>>>>...<<<.....>>>..<<<<<<...
........>>>>>>..<<...<<<<<<<...<<<<<<.......>>>>>>
.....<<...(((>>....>>>>>>>...<<<.<<<<<.......>>>>.
>>>>.<<<....>>>.>>))).......((((((..((((.>>>>>>)))
)))))))..........]]]]..}}]]]].......<<.<.<.<<<<<<.
..<<.......>>...>>>>>>...>>..>>.......<<<<<.<<<<<<
..<.<<<<<<<......>>>>>>>...>.<<<.........>>>.....>
>>>>..>...>>>.>>....<<<<<<<....>>>.>>>>....}}..}}}
.]]]]]....<<<<<<<..<<<<.<.<<<<<.................>>
>>>.><<<<<...<<<<....<<<<<<<<<<....>>>>>..>>>>>...
>>>>..>>>>>.<<<<...<<<<<...........>>>>>...>>>>.>>
>>....>>>>>>>.....<<<<<....<<<......<<.......<<...
....>>...>>........<<<<.....<<<.<<<<<.......>>>>>.
>>>....>>>>..............>>>...>>>>>...<<<<<<<....
.........>>....<<<<<<<<<.<<<....<<<<.<..<<<<<.....
.>>>>>..>>>>>...>>>....>>>>..>>>>>...>>>>> |
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| PDB | 7old High-resolution structures of a thermophilic eukaryotic 80S ribosome reveal atomistic details of translocation. |
| Resolution | 3.0 Å |
Binding residue
(original residue number in PDB) | S2 H3 E7 A8 R10 H11 S13 A15 F16 P18 R19 K20 R21 H25 K30 S31 M53 T55 A75 Y92 P96 L99 R100 S101 L102 T104 R116 R117 Y119 K120 N121 Y123 K124 K128 A129 K132 Y133 R151 Y155 R160 Q174 K175 K176 E181 K223 G224 H225 G226 F227 G229 R233 R241 K242 H244 K245 L247 R248 K249 A251 C252 I253 W256 H257 S259 H260 V261 T264 R267 A268 H275 R276 T277 M309 G310 R314 Y315 S328 V329 R335 R349 S364 E365 F366 H368 M381 K385 K386 |
Binding residue
(residue number reindexed from 1) | S1 H2 E6 A7 R9 H10 S12 A14 F15 P17 R18 K19 R20 H24 K29 S30 M52 T54 A74 Y91 P95 L98 R99 S100 L101 T103 R115 R116 Y118 K119 N120 Y122 K123 K127 A128 K131 Y132 R150 Y154 R159 Q173 K174 K175 E180 K222 G223 H224 G225 F226 G228 R232 R240 K241 H243 K244 L246 R247 K248 A250 C251 I252 W255 H256 S258 H259 V260 T263 R266 A267 H274 R275 T276 M308 G309 R313 Y314 S327 V328 R334 R348 S363 E364 F365 H367 M380 K384 K385 |
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| Enzyme Commision number |
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