Structure of PDB 8g6j Chain LA Binding Site BS01

Receptor Information

>8g6j Chain LA (length=251) Species: 9606 (Homo sapiens)

GRVIRGQRKGAGSVFRAHVKHRKGAARLRAVDFAERHGYIKGIVKDIIHD
PGRGAPLAKVVFRDPYRFKKRTELFIAAEGIHTGQFVYCGKKAQLNIGNV
LPVGTMPEGTIVCCLEEKPGDRGKLARASGNYATVISHNPETKKTRVKLP
SGSKKVISSANRAVVGVVAGGGRIDKPILKAGRAYHKYKAKRNCWPRVRG
VAMNPVEHPFGGGNHQHIGKPSTIRRDAPAGRKVGLIAARRTGRLRGTKT
V

Ligand information

>8g6j Chain S2 (length=1701)

uaccugguugauccugccaguagcauaugcuugucucaaagauuaagcca
ugcaugucuaaguacgcacggccgguacagugaaacugcgaauggcucau
uaaaucaguuaugguuccuuuggucgcucgccacuuggauaacuguggua
auucuagagcuaauacaugccgacgggcgcugacccccuucgcggggggg
augcgugcauuuaucaguggugacucuagauaaccucgggccgaucgcac
gccccccguggcggcgacgacccauucgaacgucugcccuaucaacuuuc
gaugguagucgccgugccuaccauggugaccacgggugacggggaaucag
gguucgauuccggagagggagccugagaaacggcuaccacauccaaggaa
ggcagcaggcgcgcaaauuacccacucccgacccggggagguagugacga
aaaauaacaauacaggacucuuucgaggcccuguaauuggaaugagucca
cuuuaaauccuuuaacgaggauccauuggagggcaagucuggugccagca
gccgcgguaauuccagcuccaauagcguauauuaaaguugcugcaguuaa
aaagcucguaguuggaucuugggagcgggcguccccgccuuuacuuugaa
aaaauuagaguguucaaagcaggcccgagccgccuggauaccgcagcuag
gaauaauggaauaggaccgcgguucuauuuuguugguuuucggaacugag
gccaugauuaagagggacggccgggggcauucguauugcgccgcuagagg
ugaaauucuuggaccggcgcaagacggaccagagcgaaagcauuugccaa
gaauguuuucauuaaucaagaacgaaagucggagguucgaagacgaucag
auaccgucguaguuccgaccauaaacgaugccgaccggcgaugcggcggc
guuauucccaugacccgccgggcagcuuccgggaaaccaaagucuuuggg
uuccggggggaguaugguugcaaagcugaaacuuaaaggaauugacggaa
gggcaccaccaggaguggagccugcggcuuaauuugacucaacacgggaa
accucacccggcccggacacggacaggauugacagauugauagcucuuuc
ucgauuccgugggugguggugcauggccguucuuaguugguggagcgauu
ugucugguuaauuccgauaacgaacgagacucuggcaugcuaacuaguua
cgcgacccccgagcggucggcgucccccaacuucuuagagggacaagugg
cguucagccacccgagauugagcaauaacaggucugugaugcccuuagau
guccggggcugcacgcgcgcuacacugacuggcucagcgugugccuaccc
uacgccggcaggcgcggguaacccguugaaccccauucgugauggggauc
ggggauugcaauuauuccccaugaacgaggaauucccaguaagugcgggu
cauaagcuugcguugauuaagucccugcccuuuguacacaccgcccgucg
cuacuaccgauuggaugguuuagugaggcccucggaucggccccgccggg
gugcccuggcggagcgcugagaagacggucgaacuugacuaucuagagga
aguaaaagucguaacaagguuuccguaggugaaccugcggaaggaucauu
a

...<<<<<.[.((((>>>>><<<.<<<<<<...<.<<..<......<<<.
<<<..<<....<<....<<..........>>...>>.>>......<<...
.....<<<.<....<<....<<<<<..........<<.....<<.<<<..
...>>>.>>......>>.........<<<<...<<<<<......>>>>>.
..>>>><<..<<<<<...<......>..>>>>>......>>...<<<<.<
<<<......>>>>>>>>.>>.>>>...>>..>.>>>.<<<....<<<...
.<<<<<<<.........>>>>>>>>>>......>>>...<<<.<<<<...
.>>>>....>>>.>>.<<.<<<..........>>>.>>.<.<<....>>.
>...>>>>>>.........<<<....<<<<...>>>>..>>>..>...>>
.>.....<<<<<<<<<.<<<....>>>..>>>>>.>>>>......<<..<
...........>..>>.........<<<<<((....<.<<<<.....<<.
.))>>.......>>>>>>>>>>..>>>>>>.>>>.........<.<((..
...<.<<...<<<.<<........................<<<<<<.<..
.....<<...<.......>.<<<<.......>>>>...>>......>.>>
>..>>>........<.<<.<<<<<<<...............>>>>>>>.>
>.>....>>....<<<<<<..<...<<<<..<<..<<<<<<<<...<<<.
.....>>>......>>>>>>>>..>>.......<<....>>...>>>>..
>..>>>.>>>...>>>...>>.>....<<<<<<<...<...<<<<.<...
..>.>>>>...>>>>>>>>..........<<<.<<.<<<..<.<<<<<<.
<<<<......>>>>>>>>>>.>..>>>...<<..))>>...>>.....>>
>.>.>.<<<......<<<......>>>....>>>..)))).]<<<<<.<<
<<<<<..<<..<<<<<..<<<.<<<<<.......<<........>>....
......<<<<<......<<<<<<.......<<.<<<........>>>.>>
.....>>>>>>.<.<<.<<<..<<.<<<<<<....<<<.<<<<<....>>
>...<<<......>>>...>>.>>>....<<<...<...<<<<..<<<<<
<<<<<<<.......>>>>.>>>>.....>>>>..>>>>..>.....<<<<
<.....>>>>>........>>>....>>>.>>>.....>>>>>>>>....
..>>>>>....>.>>>>.>>>.....<<.<<<........<.......<<
<.<<<<....>>>>.>>>....>.........>>>.>>............
<<<<<..........>>>>>...........>>>>>.....<<<<<<<<.
......>>>>>>>>......>>...>>>>>>>>>>.>>....<..<<.<.
.<<<<.<<....<<<<<<<<.<<<..<<<<.<<...<<<<<.<<<<<...
.......>>>>>...>>>>>...>>.>>>>..>>>.>>>>>>>>...>>.
>>>>...>.>>...>.....<<<<<<<<<<..>>>>>>>>>>........
.

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8g6j mRNA decoding in human is kinetically and structurally distinct from bacteria.
• Resolution: 2.8 Å
• Binding residue (original residue number in PDB): R247 G248 T249
• Binding residue (residue number reindexed from 1): R246 G247 T248

Gene Ontology

--> -->

UnboundLocalError

Python 3.6.8: /usr/bin/python3 Mon Dec 2 21:48:38 2024

A problem occurred in a Python script. Here is the sequence of function calls leading up to the error, in the order they occurred.

 /var/www/html/BioLiP/pdb.cgi in <module>()

   1435     title=pdb2title(pdbid)

   1436     if bs.startswith("BS"):

=> 1437         pubmed,uniprot=display_interaction(pdbid,asym_id,bs,title)

   1438     else:

   1439         if lig3:

pubmed = '', uniprot = '', display_interaction = <function display_interaction>, pdbid = '8g6j', asym_id = 'LA', bs = 'BS01', title = 'mRNA decoding in human is kinetically and structurally distinct from bacteria.'

 /var/www/html/BioLiP/pdb.cgi in display_interaction(pdbid='8g6j', asym_id='LA', bs='BS01', title='mRNA decoding in human is kinetically and structurally distinct from bacteria.')

   1295         display_ec(ec,csaOrig,csaRenu)

   1296     if go:

=> 1297         display_go(go,uniprot,pdbid,asym_id)

   1298     return pubmed,uniprot

   1299 

global display_go = <function display_go>, go = '0003723,0003735,0005840,0006412,0015934', uniprot = '', pdbid = '8g6j', asym_id = 'LA'

 /var/www/html/BioLiP/pdb.cgi in display_go(go='0003723,0003735,0005840,0006412,0015934', uniprot='', pdbid='8g6j', asym_id='LA')

    480         '''.replace("$namespace_link",namespace_link

    481           ).replace("$namespace",namespace

=>  482           ).replace("$uniprot",u

    483         ))

    484         for l,(term,name) in enumerate(go2aspect[Aspect]):

u undefined

UnboundLocalError: local variable 'u' referenced before assignment
      args = ("local variable 'u' referenced before assignment",)
      with_traceback = <built-in method with_traceback of UnboundLocalError object>