Structure of PDB 6gsj Chain L5 Binding Site BS01

Receptor Information
>6gsj Chain L5 (length=48) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKRTWQPNRRKRAKTHGFRARMRTPGGRKVLKRRRQKGRWRLTPAVRK
Ligand information
>6gsj Chain 14 (length=2811) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
agaugguaagggcccacgguggaugccucggcacccgagccgaugaagga
cguggcuaccugcgauaagccagggggagccgguagcgggcguggauccc
uggauguccgaaugggggaacccggccggcgggaacgccggucaccgcgc
uugcgcggggggaaccuggggaacugaaacaucucaguacccagaggaga
ggaaagagaaaucgacucccugaguagcggcgagcgaaaggggaccagcc
uaaaccguccggcuuguccgggcggggucguggggcccucggacaccgaa
uccccagccuagccgaagcuguugggaagcagcgccagagagggugaaag
ccccguaggcgaaagguggggggauaggugaggguacccgaguaccccgu
gguucguggagccaugggggaaucugggcggaccaccgccuaaggcuaag
uacuccgggugaccgauagcgcaccaguaccgugagggaaaggugaaaag
aaccccgggaggggagugaaauagagccugaaaccgugggcuuacaagca
gucacggccccgcaagggguuguggcgugccuauugaagcaugagccggc
gacucacggucgugggcgagcuuaagccguugaggcggaggcguagggaa
accgaguccgaacagggcgcaaacggcgaaaaguccgcggccguggaccc
gaaaccgggcgagcuagcccuggccagggugaagcuggggugagacccag
uggaggcccgaaccggugggggaugcaaaccccucggaugagcuggggcu
aggagugaaaagcuaaccgagcccggagauagcugguucuccccgaaaug
acuuuagggucagccucaggcgcugacuggggccuguagagcacugauag
ggcuaggaccaaacccugucaaacuccgaagggucccagguggagccugg
gagugagggcgcgagcgauaacguccgcguccgagcgcgggaacaaccga
gaccgccagcuaaggcccccaagucugggcuaagugguaaaggauguggc
gccgcggacauggucgaguggcgccgcgccgaaaaugaucggggcuuaag
cccagcgccgaagcugcgggucugggggaugaccccaggcgguaggggag
cguucccgaugccgaugaaggccgacccgcgagggcggcuggagguaagg
gaagugcgaaugccggcaugaguaacgauaaagagggugagaaucccucu
cgccguaagcccaaggguuccuacgcaauggucgucagcguaggguuagg
cgggaccuaaggugaagccgaaaggcguagccgaagggcagccgguuaau
auuccggcccuucccgcaggugcgauggggggacgcucuaggcuaggggg
accggagccauggacgagcccggccagaagcgcagggugggagguaggca
aauccgccucccaacaagcucugcgugguggggaagcccguacgggugac
aaccccccgaagccagggagccaagaaaagccucuaagcacaaccugcgg
gaacccguaccgcaaaccgacacaggugggcgggugcaagagcacucagg
cgcgcgggagaacccucgccaaggaacucugcaaguuggccccguaacuu
cgggagaaggggugcucccuggggugaugagccccggggagccgcaguga
acaggcucuggcgacuguuuaccaaaaacacagcucucugcgaacucgua
agaggagguauagggagcgacgcuugcccggugccggaaggucaagggga
ggggugcaagccccgaaccgaagccccggugaacggcggccguaacuaua
acgguccuaagguagcgaaauuccuugucggguaaguuccgaccugcacg
aaaagcguaacgaccggagcgcugucucggcgagggacccggugaaauug
aacuggccgugaagaugcggccuacccguggcaggacgaaaagaccccgu
ggagcuuuacugcagccugguguuggcucuuggucgcgccuguaggauag
gugggagccugugaacccccgccuccgggugggggggaggcgccggugaa
uaccacccuggcgcggcugggggccuaacccucggauggggggacagcgc
uuggcgggcaguuugacuggggcggucgccuccuaaaagguaacggaggc
gcccaaagguccccucaggcgggacggaaauccgccggagagcgcaaggg
uagaagggggccugacugcgaggccugcaagccgagcaggggcgaaagcc
gggccuagugaaccgguggucccguguggaagggccaucgaucaacggau
aaaaguuaccccggggauaacaggcugaucucccccgagcguccacagcg
gcggggagguuuggcaccucgaugucggcucgucgcauccuggggcugaa
gaaggucccaaggguugggcuguucgcccauuaaagcggcacgcgagcug
gguucagaacgucgugagacaguucggucucuauccgccacgggcgcagg
aggcuugaggggggcucuuccuaguacgagaggaccggaagggacgcacc
ucugguuucccagcugucccuccaggggcauaagcuggguagccaugugc
ggaagggauaaccgcugaaagcaucuaagcgggaagcccgccccaagaug
aggccucccacggcgucaagccgguaaggacccgggaagaccacccggug
gaugggccggggguguaagcgccgcgaggcguugagccgaccggucccaa
ucguccgaggu
.........<<<<<<<<<<<.....<<..<<<<<<<<<<<<......<<<
<<<.((..((.>>>.....<<<<<<<..<<<))..)).>>>.....>>>>
>>>...>>>....<<<....>>><<<<<<<<....>>>>>>>>.<<<<<<
..>>>>>>.>>...<<<<<<.....<<....>>......>>>>>.>....
.....<<....>>...<<<<<.....<<.....>>....>>>>>...<<<
....<<<<<<<<.....>>>>>>>>......<<<<<<<<<....<<<...
<<<<<.<<<<.<<<...<<<<<......>>>>>((......<<<.....)
)>>>...>>>...>>>>..>>>>>..>>>>>>>>>.>>>.....<<<<<<
<<<.......>>>>>>>>>......<<<<<..((((>>>>>..>>>....
..>>.>>>>>>.>>...............<<....>>....>>.......
..<<<<....>>>>..................>>>>>>>>>>>.......
<<<<<<<<<<<....>>>>>>>>>>>...<............>.<<<<<<
....<<<<<<<<<<<<<..<<<...<<<.....>>>...>>>...<<...
.>>..<<<<.....>>>>..............>>>>>>>>>>>>>..<<.
<...<<<<<<.....<<<<<<<<<..<<<....<<<<<<......>>>>>
>.....>>>...<<<..<<<<........>>>>.>>>....>>>>>>>>>
...<<<.....>>>......>>>>>>......>.>>..<<<<<<....<<
<<<....>>>>><<<<<<<<<.....<<<<<<<<<...<<<...<<<<<<
<<...........>>>>>>>>..>>.>...>>>>>>>>>.....>>>>>>
>.>>..<<<<<<<.<<......>>.>>>>>>>.....<<<......>>>.
..<<<<.<<<...<<<(((.....<<<<<<...........<<..<<<<<
<<<<..............>>>>>>>>>.>>..........)))......>
>>>>>.>>>...>>>>>>><<<<<<<<.....>>>>>>>>....>>>>>>
<.<<<<<...<<<......<<<<<.<<<....>>>>>>>>...>>>..>>
>>>..>.....>>>>>><......<<.....<<<<<<.......>>>>>>
<<<<....<<<<<.<<...<<<<<<...<<.....>>.>>>>>>....((
<<<<.<<...<<<...<<<....>>>...>>>...>>...<<<<<.....
...>>>>>))<<<<<<<<<<<<<...<<<<....<<<<<.<<<..<<<<<
.<<<<.<<..[[[[...>>>>>><<<...<<<<<<<<<<<<<<<<.<<..
...>>>>>>>>>.....>>>>>>>>>..>>><...<<<<....>>>>...
..>>>>>>...>>>..>>>>>.........>>>>...>>...>>>>>>>>
>>>>>>>..>>.....<<......>>>>>>>.<<<<<....>>>>>..>>
>>..<<<<....<<<<<<<<.<<.........<.....<<<<<.....<.
.>......>>>>><<<<<<<<<<<<.....>>>>>>>>>>>>........
....<<<<<<<<<..<<<.........>>>..<<<<<<<.....<<<...
.>>>.......>>>>>>>.<<<<<.<<<..<<<<<<<..<<<...<<...
<<<<<....>>>>>...>>...>>>>>>>>..>>>>><<<<<<.......
>>>>>>........<...........<<<<<<.....>>>>>>.....>.
...>>>>>..>>.>>>>>>>..>..>>.>>>>>>>>.>>>>>>.....>.
....<<<<<........>>>>>..<<<<<<<<.<<<.........<<<<.
<<<<<<..<<<<<.<<<.<<<<<.<<<<<<<<.<<<<<<<.........<
<.....<<<......<<<<<<<<<..>>>>>>>>>...>>>.........
.....>>..>>>>>>>.>>>>>>>>...<<<<<....>>>>>....>>>>
>.>>>..>>>>>..<<<<.....>>>><<<<<<...........>>>>>>
..<<...<<<<<<<...<<<<<<.......>>>>>>.....<<...(((>
>....>>>>>>>...<<<<..<<<......>>>..>>>>.<<<....>>>
.>>))).......<<<<<<<.<<..))))..>>>>>>>>>..........
...>>>>..>>>>>>.......<<<<...<<<<<<...<<.......>>.
..>>>>>>....>>>.>.......<<<<<.<<<<<<..<<<<<<<<<...
...>>>>>>..>>>.<<<<<.....>>>>>.....>>>>>..>...>>>.
>>....<<<<<<<....>>>.>>>>........>>>>>>>>>>>....<<
<<<<<...<<<<..<<<<<<<...............>>>>>>>.<<<<<.
..<<<<...<<<<<<<<<<<]]]]>>>>>>...>>>>>...>>>>.>>>>
>...<<<....<<<<<...........>>>>>....>>>.>>>>......
.>>>>>>>...<<.......>>.....<<<<<<<<<.......>>>>>..
..<<<<<<<<.<<<....<<<<<....>>>>>...>>>..>>>>>.>>>.
..>>>>.....
Receptor-Ligand Complex Structure
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PDB6gsj Tautomeric G•U pairs within the molecular ribosomal grip and fidelity of decoding in bacteria.
Resolution2.96 Å
Binding residue
(original residue number in PDB)
M1 K2 R3 T4 W5 Q6 P7 N8 R9 R10 K11 R12 A13 K14 H16 G17 F18 R19 R21 P25 G26 R28 K29 V30 K32 R33 R34 K37 G38 R39 W40 K48
Binding residue
(residue number reindexed from 1)
M1 K2 R3 T4 W5 Q6 P7 N8 R9 R10 K11 R12 A13 K14 H16 G17 F18 R19 R21 P25 G26 R28 K29 V30 K32 R33 R34 K37 G38 R39 W40 K48
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:6gsj, PDBe:6gsj, PDBj:6gsj
PDBsum6gsj
PubMed29931292
UniProtP80340|RL34_THET8 Large ribosomal subunit protein bL34 (Gene Name=rpmH)

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