Structure of PDB 8hl5 Chain L37E Binding Site BS01

Receptor Information
>8hl5 Chain L37E (length=54) Species: 330779 (Sulfolobus acidocaldarius DSM 639) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKGTPSFGKMNKTPTHVRCRRCGRNSFNARKGYCAACGFGRSKKIRRYSW
QNKK
Ligand information
>8hl5 Chain A23S (length=2991) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aagccucccgguggauggcucggcucgggcaccgaagaagggcgcggcaa
gcagcgaaaugcucgggugaggcgcaagcagccguugaccccgagguccc
cuaaugggauauccugccggguuccggcgcccgguuuauaacuggguggg
aaccccccgaacggaaacaucuuaguagggggaggaaaagaaaucaauug
agauccccugaguaggggcgaccgaaagggggacagcccaaacuaaaccu
gccgaugauaagucgguggggaugugguguuacgaccucuagccugaggu
ugaccucggcuuuccuaaccuaucuagccgaacuccccuggaacgggggg
ccauagagggugaaagccccguaggcuaaagauagguggaaaguggcuag
agguagaguaccauccccugguuugggggugggaaguuaggggacacgug
ccucuaaggcuaaauaugucccgagaccgauagcaaacuaaguaccguga
gggaaagcugaaaagaaccccggaagggggagugcaaagagccugaaacc
gggugguuauacaggguguggcucgaaagaagugaacccuuccgaaggaa
aggggcgcaagcccuuaguacgaggaagggcgaucggggucacgccuuuc
gucuugaaacacgggccggggaguucacaucaguggcgagcuuaaggaga
uuaucuccgaaggcauagggaaaccaagugcccgcagccuaguuucuagg
cgaggggcagggucugucagggccugaagccacugaugugaggcuagaaa
ccgggcgaucuaguccggggcaggcugaaggugggggaaaccccacugga
gggccgaauagggguucugacgugcaauucguucccuugaccucggacua
ggggcaaaagaccaaucuagcccggugauagcuaguuccccccgaaaugc
guccuagcgcagccucccuaaaggcagcucgcgggguagagugacagauc
gggggcuccaggcgccuggggcuuccggucuaacuccgaacccacgagcg
ccgaagaaggggggagugggucacucggcguaagguuggguggcaaaagg
ggaacaacccagaccuggguuaaggccccaaagucccggcuaagugccaa
cgaaaaggcgucuccagccuuagacagcgggaaggugggcccagcagcag
ccauccucuaaggagugcguaacagcucacccgccgaggcuggaggcccu
aaagauuggucggggcucaagccgggcgccgagacccaggagggggucuc
uacugagauccucugguaggggggcgcugugaugggguagaagguggguc
gugagauccacuggacccgucacaggugcagaucccggcgguaguaacag
cgaaggggggugagaaucccccucgccggaagggcaaggguuucccggca
acguucgucagccgggaguuagcguccuaagguagggccuaauagguacc
uaccgaaagggaaagggguuaacauuccccugccucccggguaggugcgg
uaacgcaagccagacuccugacggauugggguagggagaguaggaccacc
guccuacccaagcacucaagcccuuggagagccguaacggugagaagagg
gcgaaggugugaugggccuuccguuaggaggguucuccugaucccuaguc
cccaugaaaagggagucuggaacgaucccgggagaccguaccuagaaccg
acacuggugcccgggugagaagcccaaggcgucugagggguaacccaggc
uagggaacucggcaaauuagccccguaacuucgggagaaggggugccuau
cgugguuuaacaaagccacgauaggucgcagugaccagagggaccugacu
guuuaauaaaaacauagguccccgcuagcccgaaaggguguguacggggg
cuaaauccuggccacuggugguugguuaaauccggguucaaccgggcgaa
gccccaccgaaggccggggguacccucuuaagguagccaaaugccuugcc
ggguaaguuccggcgcgcaugaauggaucaacgcggucccuacuguccca
gccuggggccucgugaacgcccugagccggugcacaguccggcaucuccc
uacaccgagagaagaccccguggagcuucaccgcagccuggcguuguccc
ucgggcguuuaugcguagaguaggugggaggggucgaaccuguccuuucg
ggggcaggggacccgaaagugaaacaccacccauggacgcucgagggacu
aaccucucgaaagagaggaacaacgucaggugggcgguucggcuggggcg
gcacucccgcgaaaagauaacacgggagcccaaaggucggcucaggcggu
acagaacgccgccguagagcgcaagggcaaaagccggccugacgugaccc
uuccaaguacggggucacgacgcgaaagcggggccuagcgaacgcucgug
cccccacacgugggggccgggcaugacagaaaaguuaccccggggauaac
agggucgucgcgggcgagagcucacaucgaccccgcgguuugcuacaucg
augucggcucuucccacccuggaggugcagcugccuccaaggguagggcu
gcccgcccguuaaaggggagcgugagcuggguuuagaccgucgcgagaca
ggucggacucuaaggguagggagugcggaccgcuugaggggaaggaaccc
cuaguacgagaggaacaggguuccggggccuccaguuuaccgguuguccg
guagggcaaugccgggcagccgcgcccugagggguaaccgcugaaagcau
cuaagcgggaaccccuccccuaaaagaggcggucaggcgccggggccuuc
cccuagaagaggggguugaugggguggggauguaagcuccaagguuguaa
gaccgaggaguuuaguccgccacucccaaucaggcuccccc
<.<<<.<<<<<<.....<<..<<<<<<<<<<<<.....<<<<<<<.((..
((.>>>.....<<<<<<...<<<))..)).>>>......>>>>>>...>>
>>...<<<....>>><<<<<<.>>>>>><<<<<<<<...>>>>>>>>>>.
..<<<<<<....<<<....>>>.....>>>>>.>.........<<....>
>..<<<<<<.....<<.....>>....>>>>>>..<<<...<<<...<<<
<<<<<<.....>>>>>>>>>.....>>>......<<<<<<<<<<<<<<<<
..>>>>>><<<<<<<...<<<<<<<.<<<.....<<<<......>>>>.(
(......<<<.....))>>>...>>>...>>>>>>>.>>>>>>>>>>>>>
>>>>......<<<<<<<<......>>>>>>>>.......<<<<.((((((
>>>>...>>>......>>.>>>>>>.>>................<<....
>>....>>.........<<<<.....>>>>.................>>>
>>>.>>>>......<<<<<<<<<<....<<......<<<<<<<...<...
.<<<<<....>>>>>.....>..>>>>>>>...>>.>>>>>>>>>>..<<
<<........>>>><<<<<<...<<<<<<<<<<<<<<..<<<...<<<<<
...>>>>>...>>>...<<....>>...<<<<<...<<<<.......>>>
>...>>>>><<<<<<....>>>>>>...>>>>>>>>>>>>>>.<<<<..<
<<<<<<.....<<<<<<<<<..<<<....<<<<<<<....>>>>>>>...
..>>>....<<<<<....<<........>>..>>>>>...>>>>>>>>>.
..<<.......>>......>>>>>>...>..>>>>..<<<<<<....<<<
<<....>>>>><<<<<<<<...<<<.<<<<<.<<<...<<<....<<<<<
<<<<<<<<<<<<<>>>>>>>>>>>>>>>>>>..>>.>...>>>.>>>>>>
>>......>>>>>>.>>..<<<<<<.<<<.....>>>.>>>>>>....<<
<......>>>...<<<<<<<...<<<(((.....<<<<<<.....<<...
.....<<<.<<<<<<<<<<.......<<<<..<<....<<.........>
>....>>.........<<......>>....>>>>...>>>>>>>>>>>>>
...........)))>>....>>>>>>.>>>...>>>>>>><<<<<<<<<<
....>>>>>>>>>>....>>>>>><<<<<<<<<.<<<.....<<<<<<<<
....>>>>>>>>...>>>>>>>>>>.>>.....>>>>>><......<<..
....<<<<<<.......>>>>>><<<<....<<<<..<<...<<<<<<..
..<.....>..>>>>>>....<.{<<<...<<<<<<.<<.....>>..>>
>>>>....>>>..<<<<<........>>>>>.><<<<<<<<.....<<<.
...>>>...<<<<<<<<<<...<<<<<<<<<..<<<<<<<<<<<<<.[[[
>>>>>>>....<<<<.<..<<<<<<.....<<<<...>>>>.....>>>>
>>...>>>>>.....<<<<<<<....>>>>>>>>>>>>>...>>>>>>>>
>.........>>>>>>>>>>......>>>>>>>>.}....>>.....<<.
.....>>.>>>><<<<.....>>>>..>>>>...<<<<.....<<<<<<<
<.<<...............<<<<<.....<..>......>>>>><<<<<<
<<<<<<<......>>>>>>>>>>>>>............<<<<<<<<<..<
<<.........>>>..<<<<<<<....<<<<....>>>>......>>>>>
>>..<<<<.<<<..<<<<<<<..<<<<...<<<<<......>>>>>...>
>>>>>>>>..>>>>><<<<<..>>>>>....................<<<
<<<.....>>>>>>..........>>>>...>>.>>>>>>>.....>>.>
>>>>>>>.>>>>>>.....>.....<<<<<........>>>>>..<<<<<
<<<.<<..<<......<<<<.<<<<<<..<<<<<.<<<<<<<<<.<<<<<
<<<<<<<<<.<<<.........<<<<<..<<<...........<.<....
.>.>.......>>>............>>>>>>>>.>>>>>>>>>>>>>>.
..<<<<<<....>>>>>>....>>>>>>>>>..>>>>>...<<<.....>
>>..<<<<<.............>>>>>.(<<...<<<<<<<...<<<<<<
.......>>>>>>.....<<)..(((>>....>>>>>>>...<<<<<<<<
<.........>>>>>>>>>.<<<....>>>.>>))).......<<<<<.<
<<<<..))))))>>>>>>>>>>..........>>>>..>>>>>>......
.<<<<...<<<<<<...<<.......>>...>>>>>>....>>>.>....
.....<<<.<.<<<<..<<<<<<<<<......>>>>>>>..>>..<<<<.
....>>>>......>>>>...>...>>>.......<<<<<<<....>>>.
>>>>....>>...>>>>>>>>>>....<<<<<<<..<<<<<..<<<<<<<
.................>>>>>>><<<<<.....<<...<<<<<<<<<<]
]].>>>>>..>>>>>...>>...>>>>>.<<<<<...<<<<<........
...>>>>>...>>>>>>>>>>......>>>>>>>.<<..>><<<<<<<<<
<<<.......>>>>>....<<<<<<<<<<<<....<<<<<..<<<<....
>>>>..>>>>>...>>>>.>>>>>.>>>...>>>>>>>...
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8hl5 Cryo-EM Structures and Translocation Mechanism of Crenarchaeota Ribosome
Resolution5.72 Å
Binding residue
(original residue number in PDB)
M1 K2 G3 T4 S6 F7 G8 K9 M10 N11 K12 T13 P14 T15 H16 R18 C19 R20 R21 R24 N25 S26 N28 R30 K31 Y33 A35 F39 R41 S42 K43 K44 I45 R47 Y48 S49 W50 K53 K54
Binding residue
(residue number reindexed from 1)
M1 K2 G3 T4 S6 F7 G8 K9 M10 N11 K12 T13 P14 T15 H16 R18 C19 R20 R21 R24 N25 S26 N28 R30 K31 Y33 A35 F39 R41 S42 K43 K44 I45 R47 Y48 S49 W50 K53 K54
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:8hl5, PDBe:8hl5, PDBj:8hl5
PDBsum8hl5
PubMed37604686
UniProtQ4JAZ9|RL37_SULAC Large ribosomal subunit protein eL37 (Gene Name=rpl37e)

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