Structure of PDB 8hkv Chain L34E Binding Site BS01

Receptor Information
>8hkv Chain L34E (length=77) Species: 330779 (Sulfolobus acidocaldarius DSM 639) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SPQQRSGSFRKVFVKLPSGKSTIHYERRKDNIARCGMCKKPLNGVKNNYT
YKYSKTEKRPERVYGGYLCHKCLESLI
Ligand information
>8hkv Chain A23S (length=2989) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aagccucccgguggauggcucggcucgggcaccgaagaagggcgcggcaa
gcagcgaaaugcucgggugaggcgcaagcagccguugaccccgagguccc
cuaaugggauauccugccggguuuccggcucccgguuuauaacugggugg
gaaccccccgaacggaaacaucuuaguagggggaggaaaagaaaucaauu
gagauccccugaguaggggcgaccgaaagggggacagcccaaacuaaacc
ugccgaugauaagucgguggggaugugguguuacgaccucuagccugagg
uugaccucggcuuuccuaaccuaucuagccgaacuccccuggaacggggg
gccauagagggugaaagccccguaggcuaaagauagguggaaaguggcua
gagguagaguaccauccccugguuugggggugggaaguuaggggacacgu
gccucuaaggcuaaauaugucccgagaccgauagcaaacuaaguaccgug
agggaaagcugaaaagaaccccggaagggggagugcaaagagccugaaac
cgggugguuauacaggguguggcucgaaagaagugaacccuuccgaagga
aaggggcgcaagcccuuaguacgaggaagggcgaucggggucacgccuuu
cgucuugaaacacgggccggggaguucacaucaguggcgagcuuaaggag
auuaucuccgaaggcauagggaaaccaagugcccgcagccuaguuucuag
gcgaggggcagggucugucagggccugaagccacugaugugaggcuagaa
accgggcgaucuaguccggggcaggcugaaggugggggaaaccccacugg
agggccgaauagggguucugacgugcaauucguucccuugaccucggacu
aggggcaaaagaccaaucuagcccggugauagcuaguuccccccgaaaug
cguccuagcgcagccucccuaaaggcagcucgcgggguagagugacagau
cgggggcuccaggcgccuggggcuuccggucuaacuccgaacccacgagc
gccgaagaaggggggagugggucacucggcguaagguuggguggcaaaag
gggaacaacccagaccuggguuaaggccccaaagucccggcuaagugcca
acgaaaaggcgucuccagccuuagacagcgggaaggugggcccagcagca
gccauccucuaaggagugcguaacagcucacccgccgaggcuggaggccc
uaaagauuggucggggcucaagccgggcgccgagacccaggagggggucu
acugagauccucugguaggggggcgcugugaugggguagaaggugggucg
ugagauccacuggacccgucacaggugcagaucccggcgguaguaacagc
gaaggggggugagaaucccccucgccggaagggcaaggguuucccggcaa
cguucgucagccgggaguuagcguccuaagguagggccuaauagguaccu
accgaaagggaaagggguuaacauuccccugccucccggguaggugcggu
aacgcaagccagacuccugacggauugggguagggagaguaggaccaccg
uccuacccaagcacucaagcccuuggagagccguaacggugagaagaggg
cgaaggugugaugggccuuccguuaggaggguucuccugaucccuagucc
ccaugaaaagggagucuggaacgaucccgggagaccguaccuagaaccga
cacuggugcccgggugagaagcccaaggcgucugagggguaacccaggcu
agggaacucggcaaauuagccccguaacuucgggagaaggggugccuauc
gugguuuaacaaagccacgauaggucgcagugaccagagggaccugacug
uuuaauaaaaacauagguccccgcuagcccgaaaggguguguacgggggc
uaaauccugccacuggugguugguuaaauccggguucaaccgggcgaagc
cccaccgaaggccggggguacccucuuaagguagccaaaugccuugccgg
guaaguuccggcgcgcaugaauggaucaacgcggucccuacugucccagc
cuggggccucgugaacgcccugagccggugcacaguccggcaucucccua
caccgagagaagaccccguggagcuucaccgcagccuggcguugucccuc
gggcguuuaugcguagaguaggugggaggggucgaaccuguccuuucggg
ggcaggggacccgaaagugaaacaccacccauggacgcucgagggacuaa
ccucucgaaagagaggaacaacgucaggugggcgguucggcuggggcggc
acucccgcgaaaagauaacacgggagcccaaaggucggcucaggcgguac
agaacgccgccguagagcgcaagggcaaaagccggccugacgugacccuu
ccaaguacggggucacgacgcgaaagcggggccuagcgaacgcucgugcc
cccacacgugggggccgggcaugacagaaaaguuaccccggggauaacag
ggucgucgcgggcgagagcucacaucgaccccgcgguuugcuacaucgau
gucggcucuucccacccuggaggugcagcugccuccaaggguagggcugc
ccgcccguuaaaggggagcgugagcuggguuuagaccgucgcgagacagg
ucggacucuaaggguagggagugcggaccgcuugaggggaaggaaccccu
aguacgagaggaacaggguuccggggccuccaguuuaccgguuguccggu
agggcaaugccgggcagccgcgcccugagggguaaccgcugaaagcaucu
aagcgggaaccccuccccuaaaagaggcggucaggcgccggggccuuccc
cuagaagaggggguugaugggguggggauguaagcuccaagguuguaaga
ccgaggaguuuaguccgccacucccaaucaggcuccccc
..<<<.<<<<<<....<<<..<<<<<<<<<<<<<....<<<<<<<.((..
((.>>>.....<<<<<<...<<<))..)).>>>......>>>>>>...>>
>>...<<<....>>><<<<<....>>>>>..<<<<<.....>>>>>.>>>
...<<<<<<....<<<....>>>.....>>>>>.>.........<<....
>>...<<<<<.....<<.....>>....>>>>>...<<<...<<<...<<
<<<<<<<.....>>>>>>>>>.....>>>......<<<<<<<<<<<<<<<
<..>>>>>><<<<<<<..<<<<<<<<.<<<.....<<<<......>>>>.
((......<<<.....))>>>...>>>...>>>>>>>>>>>>>>>>>>>>
>>>>>......<<<<<<<<......>>>>>>>>......<<<<<.(((((
(>>>>>..>>>......>>.>>>>>>.>>................<<...
.>>....>>.........<<<<.....>>>>............>....>>
>>>>.>>>.......<<<<<<<<<<....<<......<<<<<<<...<..
..<<<<<....>>>>>.....>..>>>>>>>...>>.>>>>>>>>>>..<
<<<........>>>><<<<<<....<<<<<<<<<<<<<..<<<...<<<<
<...>>>>>...>>>...<<....>>...<<<<<...<<<<.......>>
>>...>>>>><<<<<<....>>>>>>...>>>>>>>>>>>>>..<<<<..
.<<<<<<.....<<<<<<<<<..<<<....<<<<<<<....>>>>>>>..
...>>>....<<<<<....<<........>>..>>>>>...>>>>>>>>>
...<<.......>>......>>>>>>......>>>>..<<<<<<....<<
<<<....>>>>><<<<<<<<...<<<.<<<<<.<<<...<<<....<<<<
<<<<<<<<<<<<<<>>>>>>>>>>>>>>>>>>..>>.>...>>>.>>>>>
>>>......>>>>>>.>>..<<<<<<<<<<.....>>>>>>>>>>....<
<<......>>>...<<<<<<<...<<<(((.....<<<<<<.....<<..
......<<<.<<<<<<<<<<.......<<<<<.<<<...<<.........
>>...>>>.........<<......>>...>>>>>...>>>>>>>>>>>>
>...........)))>>....>>>>>>.>>>...>>>>>>><<<<<<<.<
...>.>.>>>>>>....>>>>>><<<<<<<<<.<<<.....<<<<<<<<.
...>>>>>>>>...>>>>>>>>>>.>>.....>>>>>><......<<...
...<<<<<<.......>>>>>><<<<....<<<<<<<<...<<<<<<...
.<.....>..>>>>>>....(.<<<<...<<<<<<<<<.....>>>.>>>
>>>....>>....<<<<........>>>>..)<<<<<<<<.....<<<..
..>>>...<<<<<<<<<<...<<<<<<<<<..<<<<<<<<<<<<..[[[.
>>>>>><...<<<<<...<<<<<<.....<<<<...>>>>.....>>>>>
>...>>>>>....><<<<<<<....>>>>>>>>>>>>>...>>>>>>>>>
.........>>>>>>>>>>......>>>>>>>>>>....>>>....<<..
....>>>>>>><<<<.....>>>>..>>>>...<<<<.....<<<<<<<<
.<<...............<<<<<....<<..>>.....>>>>><<<<<<<
<<<<<<......>>>>>>>>>>>>>............<<<<<<<<<..<<
<.........>>>..<<<<<<<....<<<<....>>>>......>>>>>>
>..<<<<.<<..<<<<<<<..<<<....<<<<<......>>>>>....>>
>>>>>>..>>>>.<<<<<..>>>>>....................<<<<<
<.....>>>>>>..........>>>>...>>.>>>>>>>.....>>.>>>
>>>>>.>>>>>>.....>.....<<<<<........>>>>>..<<<<<<<
<.<<..<<......<<<<.<<<<<<..<<<<<.<<<<<<<<<.<<<<<<<
<<<<<<<<<<<.........<<<<<..<<<......<.<<.<<<.....>
>>>.>>...>>>............>>>>>>>>>>>>>>>>>>>>>>>...
<<<<<<....>>>>>>....>>>>>>>>>..>>>>>...<<<.....>>>
..<<<<<.............>>>>>..<<...<<<<<<<...<<<<<<..
.....>>>>>>.....<<...(((>>....>>>>>>>...<<<<<<<<<.
........>>>>>>>>>.<<<....>>>.>>))).......<<<<<.<<<
<<..))))))>>>>>>>>>>..........>>>>..>>>>>>.......<
<<<.<.<<<<<<...<<.......>>...>>>>>>...>>>>.>......
.<.<<<.<<<<<<..<<<<<<<<<......>>>>>>..>>>..<<<<...
..>>>>......>>>>>..>...>>>..>....<<<<<<<....>>>.>>
>>....>>...>>>>>>>>>>....<<<<<<<..<<<<<..<<<<<<<..
...............>>>>>>><<<<<.....<<...<<<<<<<<<<]]]
.>>>>>..>>>>>...>>...>>>>>.<<<<<...<<<<<..........
.>>>>>...>>>>>>>>>>......>>>>>>>.<<..>><<<<<<<.<<<
<.......>>>>.....<<<<<<<<<<<<....<<<<<..<<<<....>>
>>..>>>>>...>>>>.>>>>>.>>>...>>>>>>>...
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8hkv Cryo-EM Structures and Translocation Mechanism of Crenarchaeota Ribosome
Resolution4.94 Å
Binding residue
(original residue number in PDB)
S3 P4 Q5 F11 R12 K13 F15 V16 K17 L18 P19 S20 G21 S23 H26 K31 D32 N33 I34 A35 R36 C37 G38 M39 N45 G46 Y55 K57 T58 E59 K60 R61 E63 R64 V65 Y66 Y69
Binding residue
(residue number reindexed from 1)
S1 P2 Q3 F9 R10 K11 F13 V14 K15 L16 P17 S18 G19 S21 H24 K29 D30 N31 I32 A33 R34 C35 G36 M37 N43 G44 Y53 K55 T56 E57 K58 R59 E61 R62 V63 Y64 Y67
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:8hkv, PDBe:8hkv, PDBj:8hkv
PDBsum8hkv
PubMed37604686
UniProtO05981|RL34_SULAC Large ribosomal subunit protein eL34 (Gene Name=rpl34e)

[Back to BioLiP]