Structure of PDB 7a5g Chain L3 Binding Site BS01

Receptor Information
>7a5g Chain L3 (length=115) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AIQKMTRVRVVDNSALGNSPYHRAPRCIHVYKKNGVGKVGDQILLAIKGQ
KKKALIVGHCMPGPRMTPRFDSNNVVLIEDNGNPVGTRIKTPIPTSLRKR
EGEYSKVLAIAQNFV
Ligand information
>7a5g Chain A3 (length=1503) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcuaaaccuagccccaaacccacuccaccuuacuaccagcaaccuuagcc
aaaccauuuacauaaaguauaggcgauagaaauuguggcgcaauagauau
aguaccgcaagggaaagaugaaaaauuauaaccaagcauaauauagcaag
gacuaaccccuauaccuucugcauaaugaauuaacuagaaauaacuuugc
aaggagagccaaagcuaagacccccgaaaccagacgagcuaccuaagaac
agcuaagagcacacccgucuauguagcaaaauagugggaagauuuauagg
uagaggcgacaaaccuaccgagccuggugauagcugguuguccaagauag
aaucuuaguucaacuuuaaauuugcccacagaaccaaauccccuuguaaa
uuuaacuguuaguccaaagaggaacagcucuuuggacacuaggaaaaaac
cuuguagagagaguaaaaaauuuaacacccauaguaggccuaaaagcagc
caccaauuaagaaagcguucaagcucaacaccaaaaaucccaaacauaua
acugaacuccucacacccaauuggaccaaucuaucacccuauagaagaac
uaauguuaguauaaguaacaugaaaacauucuccuccgcauaagccugcg
ucagaucacacugacaauuaacagcccaauaucuacaaucaaccaacaag
ucauuauuacccucacugucaacccaacacaggcaugcucauaaggaaag
guuaaaaaaaguaaaaggaacucggcaaaucuuaccccgccuguuuacca
aaaacaucaccucuagcaucaccaguauuagaggcaccgccugcccagug
acacauguuuaacggccgcgguuaaccgugcaaagguagcauaaucacuu
guuccuuaaauagggaccuguaugaauggcuccacgaggguucagcuguc
ucuuacuuuuaaccagugaaauugaccugcccgugaagaggcgggcauaa
cacagcaagacgagaagacccuauggagcuuuaauuuauuaaugcaaaca
guaccuaacaaacccacagguccuaaacuaccaaaccugcauuaaaaauu
ucgguuggggcgaccucggagcagaacccaaccuccgagcaguacaugcu
aagacuucaccagucaaagcgaaccucaauugauccaauaacuugaccaa
cggaacaaguuacccuagggauaacagcgcaauccuauucuagaguccau
aucaacaauaggguuuacgaccucgauguuggaucaggacaucccgaugg
ugcagccgcuauuaaagguucguuuguucaacgauuaaaguccuacguga
ucugaguucagaccggaguaauccaggucgguuucuaucuacuuuauucc
ucccuguacgaaaggacaagagaaauaaggccuacuucacaaagcgccuu
cccccguaaaugauaucaucucaacuuagauacccacacccaagaacagg
guu
<<<.......<<<<....................................
<......>...........<<.....>>........>>.>>.........
....<<....>>......................>>>...........<<
<.......>>>...<.<........>.>.<<<<<<.........<<<.<<
..<<....>>...>>.>>>...<<.<..<<<<<.<.....<<<<<.<<<.
.<<<...>>>...<<<<.<<<<........>>>>>>>>....>>>.>>>>
>...<<.......>>......>.>>>>...>..>.>>..<<<<<<....<
<<<....>>>><<<.<<<<<<<<<<.....<<......>>.....>>>>>
>>>>>..>>>.<<<<<<<<<<......>>>>>>>>>>...<<<......>
>>....<<<.<<<...<..............<....<<<.........>>
>....>.......<<<......>>>.........................
..>...>>>>>>........>>>>>>...<<<<<......>>>>>.....
....>>>>>><......<<..<<<....>>><<<<..<<<<........<
<<<<......>>>>>......<<<...<<<<...................
....>>>>.......>>>.....<<......>>.>>>>.....>>>>..<
<<<...<<<<<<<<.<<.........<......<<<<<<..<<<......
...>>>...<<<<<<.............>>>>>>....<<<.<<<..<<<
<<....>>>..>>>>><<<<<....>>>>>........<...........
<<<<<<.....>>>>>>.....>....>>>....>>.>>>>.....>..>
>.>>>>>>>>>>>>.>>.....>.....<<<<<........>>>>>....
...<<..<<<.<<......<<<<.<<<<<<..<<<<<.<<<<<<<<....
.....................................>>>>>>>>>>>>>
..<<<<.....>>>><<<<<<...........>>>>>>..<<.....<<<
..<<<<.....>>>>..>>>....>>.........<<<....>>>.....
.......>>>>..>>>>>>.......<<<..<.<<<<<<...<<......
.>>...>>>>>>...>.>>.>.......<<<<<.<<<<<<..<<.<<<<<
<......>>>>>>...>>.<<<<<.....>>>>>.....>>>>>..>...
>>>.>>....<<<<<<<....>>>.>>>>....>>..>>>.>>..<<<.<
<<.................>>>.>>><<<<<...<<<....>>>.>>>>>
......<<<................>>>.........<<<<.......>>
>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7a5g Elongational stalling activates mitoribosome-associated quality control.
Resolution4.33 Å
Binding residue
(original residue number in PDB)		A31 Q33 K34 T36 R37 R53 R56 I58 H59 Y61 N64 L74 K81 C90 P92 R95
Binding residue
(residue number reindexed from 1)		A1 Q3 K4 T6 R7 R23 R26 I28 H29 Y31 N34 L44 K51 C60 P62 R65
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7a5g, PDBe:7a5g, PDBj:7a5g
PDBsum7a5g
PubMed33243891
UniProtQ6P1L8|RM14_HUMAN Large ribosomal subunit protein uL14m (Gene Name=MRPL14)

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