Structure of PDB 8hl5 Chain L24E Binding Site BS01

Receptor Information
>8hl5 Chain L24E (length=54) Species: 330779 (Sulfolobus acidocaldarius DSM 639) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RQCSFCGKDILPGTGLMYVRNDGSLLWFCSSKCRKSMLKLHRDPKKLKWT
KSYL
Ligand information
>8hl5 Chain A23S (length=2991) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aagccucccgguggauggcucggcucgggcaccgaagaagggcgcggcaa
gcagcgaaaugcucgggugaggcgcaagcagccguugaccccgagguccc
cuaaugggauauccugccggguuccggcgcccgguuuauaacuggguggg
aaccccccgaacggaaacaucuuaguagggggaggaaaagaaaucaauug
agauccccugaguaggggcgaccgaaagggggacagcccaaacuaaaccu
gccgaugauaagucgguggggaugugguguuacgaccucuagccugaggu
ugaccucggcuuuccuaaccuaucuagccgaacuccccuggaacgggggg
ccauagagggugaaagccccguaggcuaaagauagguggaaaguggcuag
agguagaguaccauccccugguuugggggugggaaguuaggggacacgug
ccucuaaggcuaaauaugucccgagaccgauagcaaacuaaguaccguga
gggaaagcugaaaagaaccccggaagggggagugcaaagagccugaaacc
gggugguuauacaggguguggcucgaaagaagugaacccuuccgaaggaa
aggggcgcaagcccuuaguacgaggaagggcgaucggggucacgccuuuc
gucuugaaacacgggccggggaguucacaucaguggcgagcuuaaggaga
uuaucuccgaaggcauagggaaaccaagugcccgcagccuaguuucuagg
cgaggggcagggucugucagggccugaagccacugaugugaggcuagaaa
ccgggcgaucuaguccggggcaggcugaaggugggggaaaccccacugga
gggccgaauagggguucugacgugcaauucguucccuugaccucggacua
ggggcaaaagaccaaucuagcccggugauagcuaguuccccccgaaaugc
guccuagcgcagccucccuaaaggcagcucgcgggguagagugacagauc
gggggcuccaggcgccuggggcuuccggucuaacuccgaacccacgagcg
ccgaagaaggggggagugggucacucggcguaagguuggguggcaaaagg
ggaacaacccagaccuggguuaaggccccaaagucccggcuaagugccaa
cgaaaaggcgucuccagccuuagacagcgggaaggugggcccagcagcag
ccauccucuaaggagugcguaacagcucacccgccgaggcuggaggcccu
aaagauuggucggggcucaagccgggcgccgagacccaggagggggucuc
uacugagauccucugguaggggggcgcugugaugggguagaagguggguc
gugagauccacuggacccgucacaggugcagaucccggcgguaguaacag
cgaaggggggugagaaucccccucgccggaagggcaaggguuucccggca
acguucgucagccgggaguuagcguccuaagguagggccuaauagguacc
uaccgaaagggaaagggguuaacauuccccugccucccggguaggugcgg
uaacgcaagccagacuccugacggauugggguagggagaguaggaccacc
guccuacccaagcacucaagcccuuggagagccguaacggugagaagagg
gcgaaggugugaugggccuuccguuaggaggguucuccugaucccuaguc
cccaugaaaagggagucuggaacgaucccgggagaccguaccuagaaccg
acacuggugcccgggugagaagcccaaggcgucugagggguaacccaggc
uagggaacucggcaaauuagccccguaacuucgggagaaggggugccuau
cgugguuuaacaaagccacgauaggucgcagugaccagagggaccugacu
guuuaauaaaaacauagguccccgcuagcccgaaaggguguguacggggg
cuaaauccuggccacuggugguugguuaaauccggguucaaccgggcgaa
gccccaccgaaggccggggguacccucuuaagguagccaaaugccuugcc
ggguaaguuccggcgcgcaugaauggaucaacgcggucccuacuguccca
gccuggggccucgugaacgcccugagccggugcacaguccggcaucuccc
uacaccgagagaagaccccguggagcuucaccgcagccuggcguuguccc
ucgggcguuuaugcguagaguaggugggaggggucgaaccuguccuuucg
ggggcaggggacccgaaagugaaacaccacccauggacgcucgagggacu
aaccucucgaaagagaggaacaacgucaggugggcgguucggcuggggcg
gcacucccgcgaaaagauaacacgggagcccaaaggucggcucaggcggu
acagaacgccgccguagagcgcaagggcaaaagccggccugacgugaccc
uuccaaguacggggucacgacgcgaaagcggggccuagcgaacgcucgug
cccccacacgugggggccgggcaugacagaaaaguuaccccggggauaac
agggucgucgcgggcgagagcucacaucgaccccgcgguuugcuacaucg
augucggcucuucccacccuggaggugcagcugccuccaaggguagggcu
gcccgcccguuaaaggggagcgugagcuggguuuagaccgucgcgagaca
ggucggacucuaaggguagggagugcggaccgcuugaggggaaggaaccc
cuaguacgagaggaacaggguuccggggccuccaguuuaccgguuguccg
guagggcaaugccgggcagccgcgcccugagggguaaccgcugaaagcau
cuaagcgggaaccccuccccuaaaagaggcggucaggcgccggggccuuc
cccuagaagaggggguugaugggguggggauguaagcuccaagguuguaa
gaccgaggaguuuaguccgccacucccaaucaggcuccccc
<.<<<.<<<<<<.....<<..<<<<<<<<<<<<.....<<<<<<<.((..
((.>>>.....<<<<<<...<<<))..)).>>>......>>>>>>...>>
>>...<<<....>>><<<<<<.>>>>>><<<<<<<<...>>>>>>>>>>.
..<<<<<<....<<<....>>>.....>>>>>.>.........<<....>
>..<<<<<<.....<<.....>>....>>>>>>..<<<...<<<...<<<
<<<<<<.....>>>>>>>>>.....>>>......<<<<<<<<<<<<<<<<
..>>>>>><<<<<<<...<<<<<<<.<<<.....<<<<......>>>>.(
(......<<<.....))>>>...>>>...>>>>>>>.>>>>>>>>>>>>>
>>>>......<<<<<<<<......>>>>>>>>.......<<<<.((((((
>>>>...>>>......>>.>>>>>>.>>................<<....
>>....>>.........<<<<.....>>>>.................>>>
>>>.>>>>......<<<<<<<<<<....<<......<<<<<<<...<...
.<<<<<....>>>>>.....>..>>>>>>>...>>.>>>>>>>>>>..<<
<<........>>>><<<<<<...<<<<<<<<<<<<<<..<<<...<<<<<
...>>>>>...>>>...<<....>>...<<<<<...<<<<.......>>>
>...>>>>><<<<<<....>>>>>>...>>>>>>>>>>>>>>.<<<<..<
<<<<<<.....<<<<<<<<<..<<<....<<<<<<<....>>>>>>>...
..>>>....<<<<<....<<........>>..>>>>>...>>>>>>>>>.
..<<.......>>......>>>>>>...>..>>>>..<<<<<<....<<<
<<....>>>>><<<<<<<<...<<<.<<<<<.<<<...<<<....<<<<<
<<<<<<<<<<<<<>>>>>>>>>>>>>>>>>>..>>.>...>>>.>>>>>>
>>......>>>>>>.>>..<<<<<<.<<<.....>>>.>>>>>>....<<
<......>>>...<<<<<<<...<<<(((.....<<<<<<.....<<...
.....<<<.<<<<<<<<<<.......<<<<..<<....<<.........>
>....>>.........<<......>>....>>>>...>>>>>>>>>>>>>
...........)))>>....>>>>>>.>>>...>>>>>>><<<<<<<<<<
....>>>>>>>>>>....>>>>>><<<<<<<<<.<<<.....<<<<<<<<
....>>>>>>>>...>>>>>>>>>>.>>.....>>>>>><......<<..
....<<<<<<.......>>>>>><<<<....<<<<..<<...<<<<<<..
..<.....>..>>>>>>....<.{<<<...<<<<<<.<<.....>>..>>
>>>>....>>>..<<<<<........>>>>>.><<<<<<<<.....<<<.
...>>>...<<<<<<<<<<...<<<<<<<<<..<<<<<<<<<<<<<.[[[
>>>>>>>....<<<<.<..<<<<<<.....<<<<...>>>>.....>>>>
>>...>>>>>.....<<<<<<<....>>>>>>>>>>>>>...>>>>>>>>
>.........>>>>>>>>>>......>>>>>>>>.}....>>.....<<.
.....>>.>>>><<<<.....>>>>..>>>>...<<<<.....<<<<<<<
<.<<...............<<<<<.....<..>......>>>>><<<<<<
<<<<<<<......>>>>>>>>>>>>>............<<<<<<<<<..<
<<.........>>>..<<<<<<<....<<<<....>>>>......>>>>>
>>..<<<<.<<<..<<<<<<<..<<<<...<<<<<......>>>>>...>
>>>>>>>>..>>>>><<<<<..>>>>>....................<<<
<<<.....>>>>>>..........>>>>...>>.>>>>>>>.....>>.>
>>>>>>>.>>>>>>.....>.....<<<<<........>>>>>..<<<<<
<<<.<<..<<......<<<<.<<<<<<..<<<<<.<<<<<<<<<.<<<<<
<<<<<<<<<.<<<.........<<<<<..<<<...........<.<....
.>.>.......>>>............>>>>>>>>.>>>>>>>>>>>>>>.
..<<<<<<....>>>>>>....>>>>>>>>>..>>>>>...<<<.....>
>>..<<<<<.............>>>>>.(<<...<<<<<<<...<<<<<<
.......>>>>>>.....<<)..(((>>....>>>>>>>...<<<<<<<<
<.........>>>>>>>>>.<<<....>>>.>>))).......<<<<<.<
<<<<..))))))>>>>>>>>>>..........>>>>..>>>>>>......
.<<<<...<<<<<<...<<.......>>...>>>>>>....>>>.>....
.....<<<.<.<<<<..<<<<<<<<<......>>>>>>>..>>..<<<<.
....>>>>......>>>>...>...>>>.......<<<<<<<....>>>.
>>>>....>>...>>>>>>>>>>....<<<<<<<..<<<<<..<<<<<<<
.................>>>>>>><<<<<.....<<...<<<<<<<<<<]
]].>>>>>..>>>>>...>>...>>>>>.<<<<<...<<<<<........
...>>>>>...>>>>>>>>>>......>>>>>>>.<<..>><<<<<<<<<
<<<.......>>>>>....<<<<<<<<<<<<....<<<<<..<<<<....
>>>>..>>>>>...>>>>.>>>>>.>>>...>>>>>>>...
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8hl5 Cryo-EM Structures and Translocation Mechanism of Crenarchaeota Ribosome
Resolution5.72 Å
Binding residue
(original residue number in PDB)
T18 S35 R38 K39 K43 R46 K50 L51 K52
Binding residue
(residue number reindexed from 1)
T14 S31 R34 K35 K39 R42 K46 L47 K48
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:8hl5, PDBe:8hl5, PDBj:8hl5
PDBsum8hl5
PubMed37604686
UniProtQ4JAV2|RL24E_SULAC Large ribosomal subunit protein eL24 (Gene Name=rpl24e)

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