Structure of PDB 8hkv Chain L24E Binding Site BS01

Receptor Information
>8hkv Chain L24E (length=54) Species: 330779 (Sulfolobus acidocaldarius DSM 639) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RQCSFCGKDILPGTGLMYVRNDGSLLWFCSSKCRKSMLKLHRDPKKLKWT
KSYL
Ligand information
>8hkv Chain A23S (length=2989) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aagccucccgguggauggcucggcucgggcaccgaagaagggcgcggcaa
gcagcgaaaugcucgggugaggcgcaagcagccguugaccccgagguccc
cuaaugggauauccugccggguuuccggcucccgguuuauaacugggugg
gaaccccccgaacggaaacaucuuaguagggggaggaaaagaaaucaauu
gagauccccugaguaggggcgaccgaaagggggacagcccaaacuaaacc
ugccgaugauaagucgguggggaugugguguuacgaccucuagccugagg
uugaccucggcuuuccuaaccuaucuagccgaacuccccuggaacggggg
gccauagagggugaaagccccguaggcuaaagauagguggaaaguggcua
gagguagaguaccauccccugguuugggggugggaaguuaggggacacgu
gccucuaaggcuaaauaugucccgagaccgauagcaaacuaaguaccgug
agggaaagcugaaaagaaccccggaagggggagugcaaagagccugaaac
cgggugguuauacaggguguggcucgaaagaagugaacccuuccgaagga
aaggggcgcaagcccuuaguacgaggaagggcgaucggggucacgccuuu
cgucuugaaacacgggccggggaguucacaucaguggcgagcuuaaggag
auuaucuccgaaggcauagggaaaccaagugcccgcagccuaguuucuag
gcgaggggcagggucugucagggccugaagccacugaugugaggcuagaa
accgggcgaucuaguccggggcaggcugaaggugggggaaaccccacugg
agggccgaauagggguucugacgugcaauucguucccuugaccucggacu
aggggcaaaagaccaaucuagcccggugauagcuaguuccccccgaaaug
cguccuagcgcagccucccuaaaggcagcucgcgggguagagugacagau
cgggggcuccaggcgccuggggcuuccggucuaacuccgaacccacgagc
gccgaagaaggggggagugggucacucggcguaagguuggguggcaaaag
gggaacaacccagaccuggguuaaggccccaaagucccggcuaagugcca
acgaaaaggcgucuccagccuuagacagcgggaaggugggcccagcagca
gccauccucuaaggagugcguaacagcucacccgccgaggcuggaggccc
uaaagauuggucggggcucaagccgggcgccgagacccaggagggggucu
acugagauccucugguaggggggcgcugugaugggguagaaggugggucg
ugagauccacuggacccgucacaggugcagaucccggcgguaguaacagc
gaaggggggugagaaucccccucgccggaagggcaaggguuucccggcaa
cguucgucagccgggaguuagcguccuaagguagggccuaauagguaccu
accgaaagggaaagggguuaacauuccccugccucccggguaggugcggu
aacgcaagccagacuccugacggauugggguagggagaguaggaccaccg
uccuacccaagcacucaagcccuuggagagccguaacggugagaagaggg
cgaaggugugaugggccuuccguuaggaggguucuccugaucccuagucc
ccaugaaaagggagucuggaacgaucccgggagaccguaccuagaaccga
cacuggugcccgggugagaagcccaaggcgucugagggguaacccaggcu
agggaacucggcaaauuagccccguaacuucgggagaaggggugccuauc
gugguuuaacaaagccacgauaggucgcagugaccagagggaccugacug
uuuaauaaaaacauagguccccgcuagcccgaaaggguguguacgggggc
uaaauccugccacuggugguugguuaaauccggguucaaccgggcgaagc
cccaccgaaggccggggguacccucuuaagguagccaaaugccuugccgg
guaaguuccggcgcgcaugaauggaucaacgcggucccuacugucccagc
cuggggccucgugaacgcccugagccggugcacaguccggcaucucccua
caccgagagaagaccccguggagcuucaccgcagccuggcguugucccuc
gggcguuuaugcguagaguaggugggaggggucgaaccuguccuuucggg
ggcaggggacccgaaagugaaacaccacccauggacgcucgagggacuaa
ccucucgaaagagaggaacaacgucaggugggcgguucggcuggggcggc
acucccgcgaaaagauaacacgggagcccaaaggucggcucaggcgguac
agaacgccgccguagagcgcaagggcaaaagccggccugacgugacccuu
ccaaguacggggucacgacgcgaaagcggggccuagcgaacgcucgugcc
cccacacgugggggccgggcaugacagaaaaguuaccccggggauaacag
ggucgucgcgggcgagagcucacaucgaccccgcgguuugcuacaucgau
gucggcucuucccacccuggaggugcagcugccuccaaggguagggcugc
ccgcccguuaaaggggagcgugagcuggguuuagaccgucgcgagacagg
ucggacucuaaggguagggagugcggaccgcuugaggggaaggaaccccu
aguacgagaggaacaggguuccggggccuccaguuuaccgguuguccggu
agggcaaugccgggcagccgcgcccugagggguaaccgcugaaagcaucu
aagcgggaaccccuccccuaaaagaggcggucaggcgccggggccuuccc
cuagaagaggggguugaugggguggggauguaagcuccaagguuguaaga
ccgaggaguuuaguccgccacucccaaucaggcuccccc
..<<<.<<<<<<....<<<..<<<<<<<<<<<<<....<<<<<<<.((..
((.>>>.....<<<<<<...<<<))..)).>>>......>>>>>>...>>
>>...<<<....>>><<<<<....>>>>>..<<<<<.....>>>>>.>>>
...<<<<<<....<<<....>>>.....>>>>>.>.........<<....
>>...<<<<<.....<<.....>>....>>>>>...<<<...<<<...<<
<<<<<<<.....>>>>>>>>>.....>>>......<<<<<<<<<<<<<<<
<..>>>>>><<<<<<<..<<<<<<<<.<<<.....<<<<......>>>>.
((......<<<.....))>>>...>>>...>>>>>>>>>>>>>>>>>>>>
>>>>>......<<<<<<<<......>>>>>>>>......<<<<<.(((((
(>>>>>..>>>......>>.>>>>>>.>>................<<...
.>>....>>.........<<<<.....>>>>............>....>>
>>>>.>>>.......<<<<<<<<<<....<<......<<<<<<<...<..
..<<<<<....>>>>>.....>..>>>>>>>...>>.>>>>>>>>>>..<
<<<........>>>><<<<<<....<<<<<<<<<<<<<..<<<...<<<<
<...>>>>>...>>>...<<....>>...<<<<<...<<<<.......>>
>>...>>>>><<<<<<....>>>>>>...>>>>>>>>>>>>>..<<<<..
.<<<<<<.....<<<<<<<<<..<<<....<<<<<<<....>>>>>>>..
...>>>....<<<<<....<<........>>..>>>>>...>>>>>>>>>
...<<.......>>......>>>>>>......>>>>..<<<<<<....<<
<<<....>>>>><<<<<<<<...<<<.<<<<<.<<<...<<<....<<<<
<<<<<<<<<<<<<<>>>>>>>>>>>>>>>>>>..>>.>...>>>.>>>>>
>>>......>>>>>>.>>..<<<<<<<<<<.....>>>>>>>>>>....<
<<......>>>...<<<<<<<...<<<(((.....<<<<<<.....<<..
......<<<.<<<<<<<<<<.......<<<<<.<<<...<<.........
>>...>>>.........<<......>>...>>>>>...>>>>>>>>>>>>
>...........)))>>....>>>>>>.>>>...>>>>>>><<<<<<<.<
...>.>.>>>>>>....>>>>>><<<<<<<<<.<<<.....<<<<<<<<.
...>>>>>>>>...>>>>>>>>>>.>>.....>>>>>><......<<...
...<<<<<<.......>>>>>><<<<....<<<<<<<<...<<<<<<...
.<.....>..>>>>>>....(.<<<<...<<<<<<<<<.....>>>.>>>
>>>....>>....<<<<........>>>>..)<<<<<<<<.....<<<..
..>>>...<<<<<<<<<<...<<<<<<<<<..<<<<<<<<<<<<..[[[.
>>>>>><...<<<<<...<<<<<<.....<<<<...>>>>.....>>>>>
>...>>>>>....><<<<<<<....>>>>>>>>>>>>>...>>>>>>>>>
.........>>>>>>>>>>......>>>>>>>>>>....>>>....<<..
....>>>>>>><<<<.....>>>>..>>>>...<<<<.....<<<<<<<<
.<<...............<<<<<....<<..>>.....>>>>><<<<<<<
<<<<<<......>>>>>>>>>>>>>............<<<<<<<<<..<<
<.........>>>..<<<<<<<....<<<<....>>>>......>>>>>>
>..<<<<.<<..<<<<<<<..<<<....<<<<<......>>>>>....>>
>>>>>>..>>>>.<<<<<..>>>>>....................<<<<<
<.....>>>>>>..........>>>>...>>.>>>>>>>.....>>.>>>
>>>>>.>>>>>>.....>.....<<<<<........>>>>>..<<<<<<<
<.<<..<<......<<<<.<<<<<<..<<<<<.<<<<<<<<<.<<<<<<<
<<<<<<<<<<<.........<<<<<..<<<......<.<<.<<<.....>
>>>.>>...>>>............>>>>>>>>>>>>>>>>>>>>>>>...
<<<<<<....>>>>>>....>>>>>>>>>..>>>>>...<<<.....>>>
..<<<<<.............>>>>>..<<...<<<<<<<...<<<<<<..
.....>>>>>>.....<<...(((>>....>>>>>>>...<<<<<<<<<.
........>>>>>>>>>.<<<....>>>.>>))).......<<<<<.<<<
<<..))))))>>>>>>>>>>..........>>>>..>>>>>>.......<
<<<.<.<<<<<<...<<.......>>...>>>>>>...>>>>.>......
.<.<<<.<<<<<<..<<<<<<<<<......>>>>>>..>>>..<<<<...
..>>>>......>>>>>..>...>>>..>....<<<<<<<....>>>.>>
>>....>>...>>>>>>>>>>....<<<<<<<..<<<<<..<<<<<<<..
...............>>>>>>><<<<<.....<<...<<<<<<<<<<]]]
.>>>>>..>>>>>...>>...>>>>>.<<<<<...<<<<<..........
.>>>>>...>>>>>>>>>>......>>>>>>>.<<..>><<<<<<<.<<<
<.......>>>>.....<<<<<<<<<<<<....<<<<<..<<<<....>>
>>..>>>>>...>>>>.>>>>>.>>>...>>>>>>>...
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8hkv Cryo-EM Structures and Translocation Mechanism of Crenarchaeota Ribosome
Resolution4.94 Å
Binding residue
(original residue number in PDB)
T18 S35 R38 K39 K50 K52 W53 Y57
Binding residue
(residue number reindexed from 1)
T14 S31 R34 K35 K46 K48 W49 Y53
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:8hkv, PDBe:8hkv, PDBj:8hkv
PDBsum8hkv
PubMed37604686
UniProtQ4JAV2|RL24E_SULAC Large ribosomal subunit protein eL24 (Gene Name=rpl24e)

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