Structure of PDB 5t7v Chain L1 Binding Site BS01

Receptor Information
>5t7v Chain L1 (length=113) Species: 1280 (Staphylococcus aureus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NHKLIEAVTKSQLRTDLPSFRPGDTLRVHVRIIEGTRERIQVFEGVVIKR
RGGGVSETFTVRKISSGVGVERTFPLHTPKIEKIEVKRRGKVRRAKLYYL
RSLRGKAARIQEI
Ligand information
>5t7v Chain A (length=1419) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uggagaguuugauccuggcucaggaugaacgcuggcggcgugccuaauac
augcaagucgagcgacggcggacgggugaguaacacguggauaacuaccu
auaagacugggauaacuucgggaaaccggagcuaauaccggcgaaaguga
augucacuuauagauggauccgcgcugcauuagcuaguugguaagguaac
ggcuuaccaaggcaacgaugcauagccgaccugagagggugaucggccac
acuggaacugagacacgguccagacuccuacgggaggcagcaguagggaa
ucuuccgcaaugggcgaaagccugacggagcaacgccgcgugagugauga
aggucuucggaucguaaaacucuguuauuagggaagaacauauguguaag
uaacugugcacaucuugacgguaccuaaucagaaagccacggcuaacuac
gugccagcagccgcgguaauacguagguggcaagcguuauccggaauuau
ugggcguaaagcgcgcguaggcgguuuuuuaagucugaugugaaagccca
cggcucaaccguggagggucauuggaaacuggaaaacuugagugcagaag
aggaaaguggaauuccauguguagcggugaaaugcgcagagauauggagg
aacaccaguggcgaaggcgacuuucuggucuguaacugacgcugaugugc
gaaagcguggggaucaaacaggauuagauacccugguaguccacgccgua
aacgaugagugcuaaguguuaggggguuuccgccccuuagugcugcagcu
aacgcauuaagcacuccgccuggggaguacgaccgcaagguugaaacuca
aaggaauugacggggacccgcacaagcgguggagcaugugguuuaauucg
aagcaacgcgaagaaccuuaccaaaucuugacauccuuugacaacugcau
gguugucgucagcucgugucgugagauguuggguuaagucccgcaacgag
cgcaacccuuaagcuuaguugccaucaucucuaaguugacugccggugac
aaaccggaggaagguggggaugacgucaaaucaucaugccccuuaugauu
ugggcuacacacgugcuacaauggacaauacaaagggcagcgaaaccgcg
aggucaagcaaaucccauaaaguuguucucaguucggauuguagucugca
acucgacuacaugaagcuggaaucgcuaguaaucguagaucagcaugcua
cggugaauacguucccgggucuuguacacaccgcccgucacaccacgaga
guuuguaacacccgaagccgguggaguaaccuuuuaggagcuagccgucg
aaggugggacaaaugauuggggugaagucguaacaagguagccguaucgg
aaggugcggcuggaucacc
....<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<.........
.<<<..<<<.......>>>......<<........<<<<<<<......<<
<<<<<..<<<.....<<<<<<....>>>>>>......>>>......<...
....>.>>>>>>>....>>>>>>>.<<<....<<...<<<<<<.<.....
...>>>>>>>.>>......>>>..<<<<<<<<....>>>>...>>>>.>>
.<<<<<............>>>>>.<<<<....>>>>...>>>........
....<.<.....<<......>.>..>.>...>.>>>>>>..<<<<.....
..<<<....>>>......>>>>.......<<<..................
.......................>>>.........<<<<<((....<<<.
......<...)).>.........>>>>>>>>..>>>>>>>>>........
..<<<((.....<<<.<..<<<.<<<<<<<.<<<<<<<<<.......<<<
<<.......>>>>>.....>>>>>>>..>>>>>>>>>....<<<<<<<..
.<<<<<<<....<<<<<<<....<<<......>>>.......>>>>>>>.
..........<<....>>.>>>>>>>..>>>>>.>>....>>>..>.>>>
....<<<<<<<...<...<<<<.........>>>>...>>>>>>>>....
......<<<<<<..<<<<<<.<<<<<......>>>>>.>>>>>>...<<.
.))>>.....>>>>>>.>>>.<<<......<<<<....>>>>....>>>.
.)))).]<<<<<.<<<<<<.....<<<.<<..<<<<<<<<<<......<<
........>>..........<<<<<<<.....................<<
<<.........<.<<<<<<<....>>>..<<<<......>>>>..>>>>.
>.....<.....<.<<................>>.>......<<.<....
...>.>>...........>...........>...>>>.........>>>>
>>>...>>.>>>>>>>>.....<<..........<<<..<<.........
.......>>....>>>..........>>......<....<...<<<....
....>>>...>....>.....>>.>>>.....<.<<<<.........>>>
>.>.............>>>>>>>>>.>>.......<<...<<<<.<<<..
<<<<<<..<<<<....<.<<<<..<<<..<<<...>>>.>>>.>>>>.>.
..>>>>..>>>>>>..>>.>>>>>....>>.........<<<<<<<<<..
..>>>>>>>>>........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5t7v Structural Basis for Linezolid Binding Site Rearrangement in theStaphylococcus aureusRibosome.
Resolution3.6 Å
Binding residue
(original residue number in PDB)		R41 R106 G107 K108 R111
Binding residue
(residue number reindexed from 1)		R39 R104 G105 K106 R109
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5t7v, PDBe:5t7v, PDBj:5t7v
PDBsum5t7v
PubMed28487427
UniProtA0A077UVB6

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