Structure of PDB 8xcg Chain L Binding Site BS01

Receptor Information
>8xcg Chain L (length=232) Species: 2681611 (Escherichia phage Lambda) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MQDIRQETLNECTRAEQSASVVLWEIDLTEVGGERYFFCNEQNEKGEPVT
WQGRQYQPYPIQGSGFELNGKGTSTRPTLTVSNLYGMVTGMAEDMQSLVG
GTVVRRKVYARFLDAVNFVNGNSYADPEQEVISRWRIEQCSELSAVSASF
VLSTPTETDGAVFPGRIMLANTCTWTYRGDECGYSGPAVADEYDQPTSDI
TKDKCSKCLSGCKFRNNVGNFGGFLSINKLSQ
Ligand information
Ligand IDSF4
InChIInChI=1S/4Fe.4S
InChIKeyLJBDFODJNLIPKO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7[S]12[Fe]3[S]4[Fe]1[S]5[Fe]2[S]3[Fe]45
CACTVS 3.385S1[Fe]S[Fe]1.S2[Fe]S[Fe]2
FormulaFe4 S4
NameIRON/SULFUR CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain8xcg Chain L Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8xcg Cryo-EM structure of lambda tail with LamB
Resolution3.46 Å
Binding residue
(original residue number in PDB)		C173 Y177 C182 C205 K207 C212 N217 F221
Binding residue
(residue number reindexed from 1)		C173 Y177 C182 C205 K207 C212 N217 F221
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046872 metal ion binding
GO:0051536 iron-sulfur cluster binding
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0046718 symbiont entry into host cell
GO:0098003 viral tail assembly
GO:0099001 symbiont genome ejection through host cell envelope, long flexible tail mechanism
Cellular Component
GO:0030430 host cell cytoplasm
GO:0098015 virus tail

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8xcg, PDBe:8xcg, PDBj:8xcg
PDBsum8xcg
PubMed38760367
UniProtP03738|TIPL_LAMBD Tail tip protein L (Gene Name=L)

[Back to BioLiP]