Structure of PDB 8x5d Chain L Binding Site BS01

Receptor Information
>8x5d Chain L (length=235) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TTSYAKIEITGTLTVLTGLQIGAGDGFSAIGAVDKPVVRDPLSRLPMIPG
TSLKGKVRTLLSRQYGADTETFYRKPNEDHAHIRRLFGDTEEYMTGRLVF
RDTKLTNKDDLEARGAKTLTEVKFENAINRVTAKANLRQMERVIPGSEFA
FSLVYEVSFGTPGEEQKASLPSSDEIIEDFNAIARGLKLLELDYLGGSGT
RGYGQVKFSNLKARAAVGALDGSLLEKLNHELAAV
Ligand information
>8x5d Chain O (length=47) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gaaacuuaaaaccguguugcacugcaacccggaauucuugcacgucg
...............................................
Receptor-Ligand Complex Structure
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PDB8x5d Mycobacterium tuberculosis type III-A CRISPR/Cas system crRNA and its maturation have atypical features.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		I22 G23 A24 D26 T52 K55 G56 R59 T60 G89 D90 T91 M95 E126 N127 I129 L138 R139 Y195 G198 T201 R202
Binding residue
(residue number reindexed from 1)		I21 G22 A23 D25 T51 K54 G55 R58 T59 G88 D89 T90 M94 E125 N126 I128 L137 R138 Y194 G197 T200 R201
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004519 endonuclease activity
Biological Process
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:8x5d, PDBe:8x5d, PDBj:8x5d
PDBsum8x5d
PubMed38218299
UniProtP9WJF9|CSM3_MYCTU CRISPR system Cms endoribonuclease Csm3 (Gene Name=csm3)

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