Structure of PDB 8uua Chain L Binding Site BS01

Receptor Information
>8uua Chain L (length=142) Species: 1642 (Listeria innocua) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RTTYMAKPGEVERKWYVIDATGVSLGRLSSEVASILRGKNKPQFTPHIDT
GDFVIIINAGKIGLTGKKATDKIYYRHSQYPGGLKSRTAGEMRTNNPEKL
LELSIKGMLPKNSLGRQLFKKLHVYGGSEHEHAAQKPEVYEL
Ligand information
>8uua Chain A (length=2894) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guuaaguuagaaagggcgcacgguggaugccuuggcacuaggagccgaag
aaggacgggacuaacaccgauaugcuuuggggagcuguacguaagcguug
auccagagauuuccgaaugggggaacccacuaucuuuagucggauaguau
ccuuacgugaauacauagcgugaggaaggcagacccagggaacugaaaca
ucuaaguaccuggaggaagagaaagaaaaaucgauuuccugaguagcggc
gagcgaaacggaaagagcccaaaccaagaagcuugcuucuugggguugua
ggacacucuauacggaguuacaaaagaaaguuauaaaugaagcggucugg
aaaggcccgccaaagacgguaacagcccgguaguugaaauggcuuucccu
ccagaguggauccugaguacgacggaacacgugaaauuccgucggaaucc
gggaggaccaucucccaaggcuaaauacucccuagugaccgauagugaac
caguaccgugagggaaaggugaaaagcaccccggaaggggagugaaacag
uuccugaaaccgugugccuacaaguaguuagagcccguuaaugggugaua
gcgugccuuuuguagaaugaaccggcgaguuacgauuuguugcaagguua
agcggaaaaagcggagccguagcgaaagcgagucugaauagggcgcauaa
guaacaggucguagacccgaaaccaggugaucuacccauguccaggauga
agguaagguaauacuuacuggagguccgaacccacgcacguugaaaagug
cggggaugagguguggguagcggagaaauuccaaucgaacuuggagauag
cugguucucuccgaaauagcuuuagggcuagccucgagguaaagagucau
ggagguagagcacuguuuggacuagcgaauucagauaaacuccgaaugcc
auguacuuauacucgggagucagacugcgagugauaagauccguagucga
aagggaaacagcccagaccaccaguuaagguccccaaauauauguuaagu
ggaaaaggaugugggguugcuuagacaaccaggauguuggcuuagaagca
gccaccauugaaagagugcguaauagcucacuggucgagugaccccgcgc
cgaaaauguaccggggcuaaacauauuaccgaaacuguggaugaaccuag
guucgugguaggagagcguucuaagggcggugaagucagaccggaaggac
ugguggagcgcuuagaagugagaaugccgguaugaguagcgaaagaaggg
ugagaaucccuuccaccgaauaucuaagguuuccugaggaaggcucgucc
gcucaggguuagucgggaccuaagccgaggccgauaggcguaggcgaugg
acaacagguagagauuccuguaccagugcuaauuguuuaaccgauggggu
gacacagaaggauagggaaucgcacgaauggaaaugugcguccaagcagu
gagugugagaaguaggcaaauccgcuucuugcgaagcaugagcugugaug
gggaagcggaaguuccugauuucacgcugucaagaaaagccucuaggaag
aguaguacugcccguaccgcaaaccgacacagguagaugaggagagaauc
cuaaggugagcgagagaacucucguuaaggaacucggcaaaaugaccccg
uaacuucgggagaaggggugcucuauuagggugcaagcccgagagagccg
cagugaauaggcccaggcgacuguuuagcaaaaacacaggucucugcaaa
accguaaggugacguauaggggcugacgccugcccggugcuggaagguua
agaggagugcuuagcuucggcgaagguacgaauugaagccccaguaaacg
gcggccguaacuauaacgguccuaagguagcgaaauuccuugucggguaa
guuccgacccgcacgaaaggcgcaacgaucugggcacugucucaacgaga
gacucggugaaauuauaguaccugugaagaugcagguuacccgcgacagg
acggaaagaccccguggagcuuuacugcaaccugauauggaauguuugua
ccgcuuguacaggauagguaggagccgaagagacgugugcgcuagcauac
gaggaggcaauggugggauacuacccuggcuguaugaccauucuaacccg
ccacgcuaagcgcguggggagacagugucaggugggcaguuugacugggg
cggucgccuccuaaagaguaacggaggcgcccaaagguucccucagaaug
gauggaaaucauucgcagaguguaaaggcacaagggagcuugacugcgag
acugacaagucgagcagggacgaaagucgggcuuagugauccggugguuc
cgcauggaagggccaucgcucaacggauaaaagcuaccccggggauaaca
ggcuuaucucccccaagaguccacaucgacggggagguuuggcaccucga
ugucggcucgucgcauccuggggcuguagucggucccaaggguugggcug
uucgcccauuaaagcggcacgcgagcuggguucagaacgucgugagacag
uucggucccuauccgucgcgggcgcaggaaauuugagaggagcuguccuu
aguacgagaggaccgggauggacacaccgcugguguaccaguuguuccgc
caggagcaucgcuggguagcuauguguggcagggauaaacgcugaaagca
ucuaagcgugaagccccccucaagaugagauuucccauuucuucggaaag
uaagaucccugaaagaugaucagguagauagguuuggaguggaaguguag
cgauacauggagcggacaaauacuaaucgaucgaggacuuaacc
<<<<<<<......<<<<<<<<<<<....{[[..[[<<<<<<<[[<<....
..<<<<<<.((..((.>>>.....<<<<<<<..<<<))..)).>>>....
.>>>>>>>...>>>....<<<....>>><<<<<<<......>>>>>>>.<
<<<<<<<<.........>>>>>>>>>.>>....<<<<<<.....<<....
>>......>>>>>.>.........<<....>>..<<<<<......<<...
..>>.....>>>>>..(((....<<<<<<<<....>>>>>>>>......<
<<<<<<<<<....<<<<........<<<<<<<<<.<<<.....<<<<...
...>>>>.((......<<<.....))>>>...>>>...>>>>>>>>>.>>
>>>>>>>>..>>>>.....<<<<<<<<.........>>>>>>>>......
<<<<<..<<<<>>>>>..)))......]].>>>>>>>.]]..........
.....<<....>>....]].........<<<<....>>>>..........
...}....>>>>>>>>>>>.......<<<<..<<<<......>>>>..>>
>>...<.<........>.>.<<<<<<....<<<<<<<<<<<<<..<<<..
.<<.......>>...>>>...<<....>>..<<<<.....>>>>......
>>>>>>>>>>>>>..<<.<...<<<<<<.....<<<<<<<<<..<<<...
.<<<<<<......>>>>>>.....>>>...<<<.<<<<<........>>>
>>>>>....>>>>>>>>>...<<<.....>>>......>>>>>>......
>.>>..<<<<<<....<<<<<....>>>>><<<<<<<<.....<<<<<<<
<<.....<<<...<<<<<<<<........>>>>>>>>..>>.>.....>>
>>>.>>>>...>>>>>>.>>..<<<<<<<.<<......>>.>>>>>>>..
..<<<......>>>...<<<<.<<<...<<<(((.....<<<<<<.....
......<<..<<<<<<<<<<.......<<<<<.<<...<<<<.......>
>>>...>>.........<<......>>...>>>>>...>>>>>>>>>>.>
>...........))).....>>>>>>.>>>...>>>>>>><<<<<<<..>
>>>>>>....>>>>>><.<<<<<<<.<<......<<<<<.<<....>>.>
>>>>...>>.>>>>>>>..>.....>>>>>><......<<....<<<<<<
.......>>>>>><<<<....<<<<<.<<<..<<<<<<...<<.....>>
.>>>>>>....((<<<<.<<...<<<...<<<....>>>...>>>...>>
...<<<<<........>>>>>))<<<<<<<<.<<......<<...<<<<<
...<<<<..<<<..<<<<<.<<<<<...(((....>>>>>.<<..<<<<<
..<<<<<<<<<<<.<<.....>>>>>>>>>.....>>>>..>>>>>...>
>...........>>>>>...>>>...>>>>........>>>>>..>>..>
>.>>>>>>>>>>>>.>>>.....<<......>>>>>>>.<<<<.....>>
>>..>>>>..<<<<....<<<<<<<<.<<.........<.....<<<<<.
....<..>......>>>>><<<<<....<<<<....>>>>...>>>>>..
..........<<<<<<<<<..<<<.........>>>..<<<<<<<.....
<<<....>>>.......>>>>>>>..<<<<.<<<..<<<<<<<..<<<<.
.<<...<<<<<<.<<....>>..>>>>>>...>>..>>>>>>>>>..>>>
>><<<<<<.......>>>>>>........<...........<<<<<<...
..>>>>>>.....>....>>>>...>>.>>>>>>>..>..>>.>>>>>>>
>.>>>>>>.....>.....<<<<<........>>>>>..<<<<<<<<.((
(.[[......<<<<.[[<<<<..<<<<<.<<<<<<<<<.<<<<<.<<<<<
<.<<<.<.........<<<<<..<<<.......<<<<<<<....>>>>>>
>....>>>............>>>>>>.>>>.>>>>>>.>>>>>....<<.
<<<<<<.....>>>>>>>>.....>>>>>>>>>..>>>>>..<<<<....
.>>>><<<<<<...........>>>>>>..<<...<<<<<<<...<<<<<
<.......>>>>>>.....<<.[.(((>>....>>>>>>>...<<<<..<
<<<....>>>>..>>>>.<<<....>>>.>>)))]......<<<<<<<.(
(..>>>>..))>>>>>>>.............>>>>..]]>>>>.......
<<<<.<.<<<<<<...<<.......>>...>>>>>>...>>>>.>.....
..<<<<<.<<<<<<..<<<<<<<<<......>>>>>>..>>>.<<<<<..
...>>>>>.....>>>>>..>...>>>.>>....<<<<<<<....>>>.>
>>>....]]..)))>>>>>>>>....<<<<<<<...<<<<..<<<<<<<.
..............>>>>>>>.<<<<<...<<<<...<<<<<<<<<<<.)
))>>>>>>..>>>>>...>>>>.>>>>>...<<<.<..<<<<<.......
....>>>>>...>>>>.>>>>.......>>>>>>>..<<<<....>>>>.
...<<<<<<<<<.......>>>>>....<<<<<<<<..<<....<<<<<.
...>>>>>...>>...>>>>>.>>>...>>>>....>>>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8uua Mechanistic insights into the alternative ribosome recycling by HflXr.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		R2 T4 M6 K8 S25 G27 R28 S31 K40 H48 T66 K68 K69 K73 Y75 Y76 H78 S79 Y81 G83 E103 S105 G108 M109 N113 S114 R117 K121 H133 A135 Q136
Binding residue
(residue number reindexed from 1)		R1 T3 M5 K7 S24 G26 R27 S30 K39 H47 T65 K67 K68 K72 Y74 Y75 H77 S78 Y80 G82 E102 S104 G107 M108 N112 S113 R116 K120 H132 A134 Q135
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
GO:0017148 negative regulation of translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8uua, PDBe:8uua, PDBj:8uua
PDBsum8uua
PubMed38407413
UniProtA0A0U5AGN0

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