Structure of PDB 8uu9 Chain L Binding Site BS01

Receptor Information
>8uu9 Chain L (length=143) Species: 1642 (Listeria innocua) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RTTYMAKPGEVERKWYVIDATGVSLGRLSSEVASILRGKNKPQFTPHIDT
GDFVIIINAGKIGLTGKKATDKIYYRHSQYPGGLKSRTAGEMRTNNPEKL
LELSIKGMLPKNSLGRQLFKKLHVYGGSEHEHAAQKPEVYELR
Ligand information
>8uu9 Chain A (length=2899) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uuaaguuagaaagggcgcacgguggaugccuuggcacuaggagccgaaga
aggacgggacuaacaccgauaugcuuuggggagcuguacguaagcguuga
uccagagauuuccgaaugggggaacccacuaucuuuagucggauaguauc
cuuacgugaauacauagcgugaggaaggcagacccagggaacugaaacau
cuaaguaccuggaggaagagaaagaaaaaucgauuuccugaguagcggcg
agcgaaacggaaagagcccaaaccaagaagcuugcuucuugggguuguag
gacacucuauacggaguuacaaaagaaaguuauaaaugaagcggucugga
aaggcccgccaaagacgguaacagcccgguaguugaaauggcuuucccuc
cagaguggauccugaguacgacggaacacgugaaauuccgucggaauccg
ggaggaccaucucccaaggcuaaauacucccuagugaccgauagugaacc
aguaccgugagggaaaggugaaaagcaccccggaaggggagugaaacagu
uccugaaaccgugugccuacaaguaguuagagcccguuaaugggugauag
cgugccuuuuguagaaugaaccggcgaguuacgauuuguugcaagguuaa
gcggaaaaagcggagccguagcgaaagcgagucugaauagggcgcauaag
uaacaggucguagacccgaaaccaggugaucuacccauguccaggaugaa
gguaagguaauacuuacuggagguccgaacccacgcacguugaaaagugc
ggggaugagguguggguagcggagaaauuccaaucgaacuuggagauagc
ugguucucuccgaaauagcuuuagggcuagccucgagguaaagagucaug
gagguagagcacuguuuggacuaggggaccgaauucagauaaacuccgaa
ugccauguacuuauacucgggagucagacugcgagugauaagauccguag
ucgaaagggaaacagcccagaccaccaguuaagguccccaaauauauguu
aaguggaaaaggaugugggguugcuuagacaaccaggauguuggcuuaga
agcagccaccauugaaagagugcguaauagcucacuggucgagugacccc
gcgccgaaaauguaccggggcuaaacauauuaccgaaacuguggaugaac
cuagguucgugguaggagagcguucuaagggcggugaagucagaccggaa
ggacugguggagcgcuuagaagugagaaugccgguaugaguagcgaaaga
agggugagaaucccuuccaccgaauaucuaagguuuccugaggaaggcuc
guccgcucaggguuagucgggaccuaagccgaggccgauaggcguaggcg
auggacaacagguagagauuccuguaccagugcuaauuguuuaaccgaug
gggugacacagaaggauagggaaucgcacgaauggaaaugugcguccaag
cagugagugugagaaguaggcaaauccgcuucuugcgaagcaugagcugu
gauggggaagacggaaguuccugauuucacgcugucaagaaaagccucua
ggaagaguaguacugcccguaccgcaaaccgacacagguagaugaggaga
gaauccuaaggugagcgagagaacucucguuaaggaacucggcaaaauga
ccccguaacuucgggagaaggggugcucuauuagggugcaagcccgagag
agccgcagugaauaggcccaggcgacuguuuagcaaaaacacaggucucu
gcaaaaccguaaggugacguauaggggcugacgccugcccggugcuggaa
gguuaagaggagugcuuagcuucggcgaagguacgaauugaagccccagu
aaacggcggccguaacuauaacgguccuaagguagcgaaauuccuugucg
gguaaguuccgacccgcacgaaaggcgcaacgaucugggcacugucucaa
cgagagacucggugaaauuauaguaccugugaagaugcagguuacccgcg
acaggacggaaagaccccguggagcuuuacugcaaccugauauggaaugu
uuguaccgcuuguacaggauagguaggagccgaagagacgugugcgcuag
cauacgaggaggcaauggugggauacuacccuggcuguaugaccauucua
acccgccacgcuaagcgcguggggagacagugucaggugggcaguuugac
uggggcggucgccuccuaaagaguaacggaggcgcccaaagguucccuca
gaauggauggaaaucauucgcagaguguaaaggcacaagggagcuugacu
gcgagacugacaagucgagcagggacgaaagucgggcuuagugauccggu
gguuccgcauggaagggccaucgcucaacggauaaaagcuaccccgggga
uaacaggcuuaucucccccaagaguccacaucgacggggagguuuggcac
cucgaugucggcucgucgcauccuggggcuguagucggucccaaggguug
ggcuguucgcccauuaaagcggcacgcgagcuggguucagaacgucguga
gacaguucggucccuauccgucgcgggcgcaggaaauuugagaggagcug
uccuuaguacgagaggaccgggauggacacaccgcugguguaccaguugu
uccgccaggagcaucgcuggguagcuauguguggcagggauaaacgcuga
aagcaucuaagcgugaagccccccucaagaugagauuucccauuucuucg
gaaaguaagaucccugaaagaugaucagguagauagguuuggaguggaag
uguagcgauacauggagcggacaaauacuaaucgaucgaggacuuaacc
<<<<<<......<<<<<<<<<<<....{[[..[[<<<<<<<[[<<.....
.<<<<<<.((..((.>>>.....<<<<<<<..<<<))..)).>>>.....
>>>>>>>...>>>....<<<....>>><<<<<<<......>>>>>>>.<<
<<<<<<<.........>>>>>>>>>.>>....<<<<<<.....<<....>
>......>>>>>.>.........<<....>>..<<<<<......<<....
.>>.....>>>>>..(((....<<<<<<<<....>>>>>>>>......<<
<<<<<<<<....<<<<........<<<<<<<<<.<<<.....<<<<....
..>>>>.((......<<<.....))>>>...>>>...>>>>>>>>>.>>>
>>>>>>>..>>>>.....<<<<<<<<.........>>>>>>>>......<
<<<<..<<<<>>>>>..)))......]].>>>>>>>.]]...........
....<<....>>....]].........<<<<....>>>>...........
..}....>>>>>>>>>>>.......<<<<..<<<<......>>>>..>>>
>...<.<........>.>.<<<<<<....<<<<<<<<<<<<<..<<<...
<<.......>>...>>>...<<....>>..<<<<.....>>>>......>
>>>>>>>>>>>>..<<.<..<<<<<<<.....<<<<<<<<<..<<<....
<<<<<<......>>>>>>.....>>>...<<<.<<<<<........>>>>
>>>>....>>>>>>>>>...<<<.....>>>......>>>>>>...>..>
.>>..<<<<<<....<<<<<....>>>>><<<<<<<<.....<<<<<<<<
<.....<<<...<<<<<<<<...<<...>>...>>>>>>>>..>>.>...
..>>>>>.>>>>...>>>>>>.>>..<<<<<<<.<<......>>.>>>>>
>>....<<<......>>>...<<<<.<<<...<<<(((.....<<<<<<.
..........<<..<<<<<<<<<<.......<<<<<.<<...<<<<....
...>>>>...>>.........<<......>>...>>>>>...>>>>>>>>
>>.>>...........))).....>>>>>>.>>>...>>>>>>><<<<<<
<..>>>>>>>....>>>>>><.<<<<<<<.<<......<<<<<.<<....
>>.>>>>>...>>.>>>>>>>..>.....>>>>>><......<<....<<
<<<<.......>>>>>><<<<....<<<<<.<<...<<<<<<...<<...
..>>.>>>>>>....((<<<<.<<...<<<...<<<....>>>...>>>.
..>>...<<<<<........>>>>>))<<<<<<<<.<<......<<...<
<<<<...<<<<..<<<..<<<<<.<<<<<...(((....>>>>>.<<..<
<<<<..<<<<<<<<<<<.<<.....>>>>>>>>>.....>>>>..>>>>>
...>>............>>>>>...>>>...>>>>........>>>>>..
>>..>>.>>>>>>>>>>>>..>>.....<<......>>>>>>>.<<<<..
...>>>>..>>>>..<<<<....<<<<<<<<.<<.........<.....<
<<<<....<<..>>.....>>>>><<<<<....<<<<....>>>>...>>
>>>............<<<<<<<<<..<<<.........>>>..<<<<<<<
.....<<<....>>>.......>>>>>>>..<<<<.<<<..<<<<<<<..
<<<<..<<...<<<<<<.<<<..>>>..>>>>>>...>>..>>>>>>>>>
..>>>>><<<<<<.......>>>>>>........<...........<<<<
<<.....>>>>>>.....>....>>>>...>>.>>>>>>>..>..>>.>>
>>>>>>.>>>>>>.....>.....<<<<<........>>>>>..<<<<<<
<<.(((.[[......<<<<.[[<<<<..<<<<<.<<<<<<<<<.<<<<<.
<<<<<<.<<<.<.........<<<<<..<<<.......<<<<<<<....>
>>>>>>....>>>............>>>>>>.>>>.>>>>>>.>>>>>..
..<<.<<<<<<.....>>>>>>>>.....>>>>>>>>>..>>>>>..<<<
<.....>>>><<<<<<...........>>>>>>..<<...<<<<<<<...
<<<<<.<......>>>>>>.....<<.[.(((>>....>>>>>>>...<<
<<..<<<<....>>>>..>>>>.<<<....>>>.>>)))]......<<<<
<<<.((..>>>>..))>>>>>>>.............>>>>..]]>>>>..
.....<<<<.<.<<<<<<...<<.......>>...>>>>>>...>>>>.>
.......<<<<<.<<<<<<..<<<<<<<<<......>>>>>>..>>>.<<
<<<.....>>>>>.....>>>>>..>...>>>.>>....<<<<<<<....
>>>.>>>>....]]..)))>>>>>>>>....<<<<<<<...<<<<..<<<
<<<<...............>>>>>>>.<<<<<...<<<<...<<<<<<<<
<<<.)))>>>>>>..>>>>>...>>>>.>>>>>...<<<.<..<<<<<..
.........>>>>>...>>>>.>>>>.......>>>>>>>..<<<<<..>
>>>>....<<<<<<<<<.......>>>>>....<<<<<<<<..<<....<
<<<<....>>>>>...>>...>>>>>.>>>...>>>>....>>>>>>..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8uu9 Mechanistic insights into the alternative ribosome recycling by HflXr.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		R2 T4 K8 S25 G27 R28 S31 K40 H48 T66 K69 Y75 Y76 H78 S79 Q80 G83 L85 E103 S105 G108 M109 N113 S114 L115 R117 K121 H133 A135 Q136
Binding residue
(residue number reindexed from 1)		R1 T3 K7 S24 G26 R27 S30 K39 H47 T65 K68 Y74 Y75 H77 S78 Q79 G82 L84 E102 S104 G107 M108 N112 S113 L114 R116 K120 H132 A134 Q135
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
GO:0017148 negative regulation of translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8uu9, PDBe:8uu9, PDBj:8uu9
PDBsum8uu9
PubMed38407413
UniProtA0A0U5AGN0

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