Structure of PDB 8ro2 Chain L Binding Site BS01

Receptor Information
>8ro2 Chain L (length=555) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLD
PSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLD
KAAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEA
RARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRK
RGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGEASQDR
ILQEAQNLMALTNVDTPLKGGDVDARKQAIRDAERVKEMKRMHKAVQKDL
PRPSEVNETILRPLNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPS
GNKKGKTVGFGTNNSEHITYLEHNPYEKFSKEELKKAQDVLVQEMEVVKQ
GMSHGELSSEAYNQVWEECYSQVLYLPGQSRYTRANLAKKDRIESLEKRL
EINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAH
LELRTFEELKKHEDSAIPRRLECLKEDVQRQQEREKELQHRYADLLLEKE
TLKSK
Ligand information
>8ro2 Chain 2 (length=39) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aucgcuucucggccuuuuggcuaagaucaaguguaguau
.......................................
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8ro2 Mechanism for the initiation of spliceosome disassembly.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		N29 S32
Binding residue
(residue number reindexed from 1)		N24 S27
External links
PDB RCSB:8ro2, PDBe:8ro2, PDBj:8ro2
PDBsum8ro2
PubMed38925148
UniProtQ99459|CDC5L_HUMAN Cell division cycle 5-like protein (Gene Name=CDC5L)

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