Structure of PDB 8qsj Chain L Binding Site BS01

Receptor Information
>8qsj Chain L (length=115) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AIQKMTRVRVVDNSALGNSPYHRAPRCIHVYKKNGVGKVGDQILLAIKGQ
KKKALIVGHCMPGPRMTPRFDSNNVVLIEDNGNPVGTRIKTPIPTSLRKR
EGEYSKVLAIAQNFV
Ligand information
>8qsj Chain A (length=1418) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcuaaaccuagccccaaacccacuccaccuuacuaccagacaaccuuagc
caaaccauuuacccaaauaaaguauaggcgauagaaauugaaaccuggcg
caauagauauaguaccgcaagggaaagaugaaaaauaccaagcauaauau
agcaaggacuaaccccuauaccuucugcauaaugaauuaacuagaaauaa
cuuugcaaggagagccaaagcuaagacccccgaaaccagacgagcuaccu
aagaacagcuaaaagagcacacccgucuauguagcaaaauagugggaaga
uuuauagguagaggcgacaaaccuaccgagccuggugauagcugguuguc
caagauagaaucuuaguucaacuuuaaauuugcccacagaacccucuaaa
uccccuuguaaauuuaacuguuaguccaaagaggaacagcucuuuggaca
cuaggaaaaaaccuuguagagagaguaaaaaauuuaacacccauaguagg
ccuaaaagcagccaccaauuaagaaagcguucaagcucaacacaaaaaau
cccaaacauauaacugaacuccucacacccaauuggaccaaucuaucacc
cuauagaagaacuaauguuaguauaaguaacaugaaaacauucuccuccg
cauaagccugcgucagacacugaacugacaauuaacagcccaauaucuac
aaucaaccaacaagucauuauuacccucacugucaacccaacacaggcau
gcucauaaggaaagguuaaaaaaaguaaaaggaacucggcaaaucuuacc
ccgccuguuuaccaaaaacaucaccucuagcaucaccaguauuagaggca
ccgccgcuccacgaggguucagcugucucuuacuuuuaaccagugaaauu
gaccugcccgugaagaggcgggcauaacacagcaagacgagaagacccua
uggagcuuuaauuuauuaaugcaaacaaccugcauuaaaaauuucgguug
gggcgaccucggagcagaacccaaccuccgagcaguacaugcuaagacuu
caccagucaaagcgaacacucaauugauccaauaacuugaccaacggaac
aaguuacccuagggauaacagcgcaauccuauucuagaguccauaucaac
aauagggcgaccucgauggaucaggacaucccgauggugcagccgcuauu
aaagguucguuuaacgauuaaaguccuacgugaucugaguucagaccgga
guaauccaggucgguuucuaucuacuuaaauuccucccuguacgaaagga
caagagaaauaaggccuacuucacaaagcgccuucccccguaaaugauuc
ucaacuuaguauacccaccccacccaagaacaggguuuauauauauauau
auauauauauauauauau
<<<.......<<<<....................................
.<<....>>.........<.....<<.....>>....>........>>.>
>.............<<....>>..................>>>.......
....<<<.......>>>...<.<........>.>.<<<<<<.........
<<<.<<..<<....>>...>>.>>>...<<.<..<<<<<.<.....<<<<
<.<<<..<<<.....>>>...<<<..<<<<........>>>>.>>>....
>>>.>>>>>...<<.......>>......>.>>>>...>..>.>>..<<<
<<<....<<<<....>>>><<<.<<<<<<<<<<.....<<..........
>>.....>>>>>>>>>>..>>>.<<<<<<<<<<......>>>>>>>>>>.
..<<<......>>>....<<<.<<<...<..............<....<<
<.........>>>....>.......<<<......>>>.............
..............>...>>>>>>........>>>>>>...<<<<<....
..>>>>>.........>>>>>><......<<..<<<....>>><<<<..<
<<<........<<<<<........>>>>>......<<<...<<<<.....
..................>>>>.......>>>.....<<......>>.>>
>>.....>>>>..<<<<...<<<<<<<<.<<................<<<
<<<..<<<.........>>>...<<<<<<.............>>>>>>..
..<<.>>....>>.>>>>........>>.>>>>>>>>>>>>.>>.....>
.....<<<<<........>>>>>.......<<..<<<.<<<.....<<<<
.<<<<<<..<<<<<.<<<<<<<<.......>>>>>>>>>>>>>..<<<<.
....>>>><<<<<<...........>>>>>>..<<.....<<<..<<<<.
....>>>>..>>>.....>>.........<<<....>>>...........
.>>>>..>>>>>>.......<<<...<<<<<<<...<<.......>>...
>>>>>>>>>.>.....<<<<.<<<<<<..<<.<<<<<<......>>>>>>
...>>.<<<<<.>>>>>.....>>>>>..>...>>>>......<<<<<<<
....>>>.>>>>...>>>..>>>.>>...<<<.<<<..............
...>>>.>>><<<<<...<<<....>>>.>>>>>......<<<.......
.....>>>.............<<<<.......>>>>.<<<<<<..>>>>>
>.<<<<<<<..>>>>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8qsj Structural insights into the role of GTPBP10 in the RNA maturation of the mitoribosome.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		A31 Q33 K34 M35 T36 R37 R53 H59 Y61 K63 N64 K81 M91 R95
Binding residue
(residue number reindexed from 1)		A1 Q3 K4 M5 T6 R7 R23 H29 Y31 K33 N34 K51 M61 R65
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8qsj, PDBe:8qsj, PDBj:8qsj
PDBsum8qsj
PubMed38042949
UniProtQ6P1L8|RM14_HUMAN Large ribosomal subunit protein uL14m (Gene Name=MRPL14)

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