Structure of PDB 8q84 Chain L Binding Site BS01

Receptor Information
>8q84 Chain L (length=61) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TTDKYFIEQRNIVLQEINETMNSILNGLNGLNISLESSIAVGREFQSVSD
LWKTLYDGLES
Ligand information
>8q84 Chain e (length=11) Species: 4932 (Saccharomyces cerevisiae) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
SATEYRLSIGS
Receptor-Ligand Complex Structure
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PDB8q84 Structural mechanism of outer kinetochore Dam1-Ndc80 complex assembly on microtubules
Resolution3.15 Å
Binding residue
(original residue number in PDB)
N36 N40 N43 I47 E50
Binding residue
(residue number reindexed from 1)
N22 N26 N29 I33 E36
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0008017 microtubule binding
GO:0051010 microtubule plus-end binding
Biological Process
GO:0007059 chromosome segregation
GO:0008608 attachment of spindle microtubules to kinetochore
GO:0031116 positive regulation of microtubule polymerization
GO:0051301 cell division
GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore
GO:1990758 mitotic sister chromatid biorientation
GO:1990976 protein transport along microtubule to mitotic spindle pole body
Cellular Component
GO:0000775 chromosome, centromeric region
GO:0000776 kinetochore
GO:0005634 nucleus
GO:0005694 chromosome
GO:0005737 cytoplasm
GO:0005819 spindle
GO:0005856 cytoskeleton
GO:0005874 microtubule
GO:0005876 spindle microtubule
GO:0042729 DASH complex
GO:0044732 mitotic spindle pole body
GO:0072686 mitotic spindle

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8q84, PDBe:8q84, PDBj:8q84
PDBsum8q84
PubMed38060647
UniProtQ12248|DAD1_YEAST DASH complex subunit DAD1 (Gene Name=DAD1)

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