Structure of PDB 8pj1 Chain L Binding Site BS01

Receptor Information
>8pj1 Chain L (length=220) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DKEWMPVTKLGRLVKDMKIKSLEEIYLFSLPIKESEIIDFFLGASLKDEV
LKIMPVQKQTRAGQRTRFKAFVAIGDYNGHVGLGVKCSKEVATAIRGAII
LAKLSIVPVRRGYWGNKIGKPHTVPCKVTGRCGSVLVRLIPAPRGTGIVS
APVPKKLLMMAGIDDCYTSARGCTATLGNFAKATFDAISKTYSYLTPDLW
KETVFTKSPYQEFTDHLVKT
Ligand information
>8pj1 Chain A (length=1754) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauccugccaguagcauaugcuugucucaaagauuaagcca
ugcaugucugaguacgcacggccgguacagugaaacugcgaauggcucau
uaaaucaguuaugguuccuuuggucgcucgcuccuacuuggauaacugug
guaauucuagagcuaauacaugccgacgggcgcugacccccuucgcgggg
gggaugcgugcauuuaucaguggugacucuagauaaccucgggccgaucg
cacgccccccguggcggcgacgacccauucgaacgucugcccuaucaacu
uucgaugguagucgccgugccuaccauggugaccacgggugacggggaau
caggguucgauuccggagagggagccugagaaacggcuaccacauccaag
gaaggcagcaggcgcgcaaauuacccacucccgacccggggagguaguga
cgaaaaauaacaauacaggacucuuucgaggcccuguaauuggaaugagu
ccacuuuaaauccuuuaacgaggauccauuggagggcaagucuggugcca
gcagccgcgguaauuccagcuccaauagcguauauuaaaguugcugcagu
uaaaaagcucguaguuggaucuugggagcgggcgggcgguccgccgcgag
gcgagccaccgcccguccccgccccucucggcggcccgaagcguuuacuu
ugaaaaaauuagaguguucaaagcaggcccgagccgccuggauaccgcag
cuaggaauaauggaauaggaccgcgguucuauuuuguugguuuucggaac
ugaggccaugauuaagagggacggccgggggcauucguauugcgccgcua
gaggugaaauucuuggaccggcgcaagacggaccagagcgaaagcauuug
ccaagaauguuuucauuaaucaagaacgaaagucggagguucgaagacga
ucagauaccgucguaguuccgaccauaaacgaugccgaccggcgaugcgg
cggcguuauucccaugacccgccgggcagcuuccgggaaaccaaagucuu
uggguuccggggggaguaugguugcaaagcugaaacuuaaaggaauugac
ggaagggcaccaccaggaguggagccugcggcuuaauuugacucaacacg
ggaaaccucacccggcccggacacggacaggauugacagauugauagcuc
uuucucgauuccgugggugguggugcauggccguucuuaguugguggagc
gauuugucugguuaauuccgauaacgaacgagacucuggcaugcuaacua
guuacgcgacccccgagcggucggcgucccccaacuucuuagagggacaa
guggcguucagccacccgagauugagcaauaacaggucugugaugcccuu
agauguccggggcugcacgcgcgcuacacugacuggcucagcgugugccu
acccuacgccggcaggcgcggguaacccguugaaccccauucgugauggg
gaucggggauugcaauuauuccccaugaacgaggaauucccaguaagugc
gggucauaagcuugcguugauuaagucccugcccuuuguacacaccgccc
gucgcuacuaccgauuggaugguuuagugaggcccucggaucggccccgc
cgggggcccuggcggagcgcugagaagacggucgaacuugacuaucuaga
ggaaguaaaagucguaacaagguuuccguaggugaaccugcggaaggauc
auua
...<<<<<.[.((((>>>>><<<.<<<<<<...<.<<..<......<<<.
<<<..<<....<<....<<..........>>...>>.>>......<<...
.....<<<.<....<<....<<<<<.............<<.....<<.<<
<.....>>>.>>......>>.........<<<<...<<<<........>>
>>...>>>><<..<<<<<...<......>..>>>>>......>>...<<<
<.<<<<......>>>>>>>>.>>.>>>...>>..>.>>>.<<<....<<<
....<<<<<<<.........>>>>>>>>>>......>>>...<<<.<<<<
....>>>>....>>>.>>.<<.<<<..........>>>.>>.<.<<....
>>.>...>>>>>>.........<<<....<<<<...>>>>..>>>..>..
.>>.>.....<..<...<<..<<....>>..>>.....>...>.....<<
..<...........>..>>.........<<<<<((......<<<<.....
<<..))>>.......>>>>.>>>>>..>>>>>>.>>>.........<.<(
(.....<.<<...<<<.<<.....<..<<<<<<<<<<<<<.<<<<....>
>>>....>>>>>>>>..>>>>>.><<.............>>...<<<<<<
.<.......<<...<.......>.<<<<.......>>>>...>>......
>.>>>..>>>........<.<<.<<<.<..................>..>
>>.>>.>....>>....<<<<<<..<...<<<<..<<..<<<<<<<<...
<<<......>>>......>>>>>>>>..>>.......<<....>>...>>
>>..>..>>>.>>>...>>>...>>.>....<<<<<<<...<...<<<<.
<.....>.>>>>...>>>>>>>>..........<<<.<<.<<<..<.<<<
<<<.<<<........>>>>>>>>>.>..>>>...<<..))>>...>>...
..>>>.>.>.<<<......<<<<....>>>>....>>>..)))).]<<<<
<.<<<<<<<..<<..<<<<<..<<<.<<<<<<......<<........>>
..........<<<<<.<....<<<<<<.......<<.<<<........>>
>.>>.....>>>>>>...<<.<<<..<<.<<<<<<....<<<.<<<<<..
..>>>...<<<......>>>...>>.>>>....<<<...<...<<<<..<
<<<<<<<<<<<.......>>>>.>>>>.....>>>>..>>>>..>.....
<<<<<.....>>>>>........>>>....>>>.>>>.....>>>>>>>.
....>.>>>>>...>>.>>>>.>>>.....<<.<<<........<.....
..<<<.<<<<....>>>>.>>>....>.........>>>.>>......<.
..<.<<<<<..........>>>>>>....>.....>>>>>.....<<<<<
<<<.......>>>>>>>>......>>...>>>>>>>>>>.>>....<..<
<.<..<<<<.<<....<<<<<<<<.<<<..<<<<.<<...<<<<<.....
..................>>>>>...>>.>>>>..>>>.>>>>>>>>...
>>.>>>>...>.>>...>.....<<<<<<<<<<..>>>>>>>>>>.....
....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8pj1 Structural basis for translational control by the human 48S initiation complex from codon scanning toward subunit joining
Resolution3.4 Å
Binding residue
(original residue number in PDB)
V112 Q113 K114 Q115 R117 R123 K125 K145 K183 T185 R187 C188 G189 S190 L192 R194 V205 S206 A207 Y223 R227 C229 T230 A231 T232 N235
Binding residue
(residue number reindexed from 1)
V56 Q57 K58 Q59 R61 R67 K69 K89 K127 T129 R131 C132 G133 S134 L136 R138 V149 S150 A151 Y167 R171 C173 T174 A175 T176 N179
External links
PDB RCSB:8pj1, PDBe:8pj1, PDBj:8pj1
PDBsum8pj1
PubMed
UniProtP15880|RS2_HUMAN Small ribosomal subunit protein uS5 (Gene Name=RPS2)

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