Structure of PDB 8jh3 Chain L Binding Site BS01

Receptor Information
>8jh3 Chain L (length=45) Species: 460519 (Komagataella phaffii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GVKYTCGACAHNFSLNKSDPVRCKECGHRVIYKARTKRMIQFDAR
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8jh3 Chain L Residue 101 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8jh3 Cryo-EM structures of RNA polymerase II-nucleosome complexes rewrapping transcribed DNA
Resolution3.7 Å
Binding residue
(original residue number in PDB)
C33 C36 C50
Binding residue
(residue number reindexed from 1)
C6 C9 C23
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0001054 RNA polymerase I activity
GO:0001055 RNA polymerase II activity
GO:0001056 RNA polymerase III activity
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 DNA-templated transcription
GO:0006360 transcription by RNA polymerase I
GO:0006366 transcription by RNA polymerase II
GO:0006383 transcription by RNA polymerase III
Cellular Component
GO:0005665 RNA polymerase II, core complex
GO:0005666 RNA polymerase III complex
GO:0005736 RNA polymerase I complex

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Biological Process

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Cellular Component
External links
PDB RCSB:8jh3, PDBe:8jh3, PDBj:8jh3
PDBsum8jh3
PubMed37981206
UniProtF2QMI1

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