Structure of PDB 8c98 Chain L Binding Site BS01

Receptor Information
>8c98 Chain L (length=93) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RLNTLSPAEGSKKAGKRLGRGIGSGLKAAITAEIRLSDLAKVEGGVVDLN
TLKAANIIGIQIEFAKVILAGEVTTPVTVRGLRVTKGARAAIE
Ligand information
>8c98 Chain A (length=1018) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
agcguacacgguggaugcccuggcagucagaggcgaugaaggacgugcua
aucugcgauaagcgucgguaaggugauaugaaccguuauaaccggcgauu
uccgaauggggaaacccaguguguuucgacacacuaucauuaacugaauc
cauagguuaaugaggcgaaccgggggaacugaaacaucuaaguaccccga
ggaaaagaaaucaaccgagauucccccaguagcggcgagcgaacggggag
cagcccagagccugaaucaguguguguguuaguggaagcgucuggaaagg
cgcgcgauacagggugacagccccguacacaaaaaugcacaugcugugag
cucgaugaguagggcgggacacgugguauccugucugaauaugggggauc
cuccaaggcuaaauacuccugacugaccgauagugaaccaguaccgugag
ggaaaggcgaaaagaaccccggcgaggggagugaaaaagaaccugaaacc
guguacguacaagcagugggagcacgcuuaggcgugugacugcggucagc
gacuuauauucuguagcaagguuaaccgaauaggggagccgaagggaaac
cgagucuuaacugggcguuaaguugcaggguauagacccgaaacccggug
aaccgggagauagcugguucuccccgaaagcuauuuagguagcgccucgu
gaauucaucuccgggggagaauguuaucacgggagacacacggcgggugc
uaacguccgucgugaagagggaaacaacccagaccgccagcuaagguccc
aaagucaugguuaagggggcuaaaccaugcaccgaagcugcggcagcgac
gcuuaugcguuguuggguaggggagcguucuguaagccugcgaaggugug
cugugaggcaugcuggagguaucagaagugcgaaugcugacuuccugucc
aacguuaaucggggcagggugagucgaaacagguuaauauuccuguacuu
ggugaucaaaucguaccc
.<<<<<<<<<<<....<<<..<<<<<<<<<<<<<......<<<<<<....
(((.>>>.....<<<<<<<..<<<)))....>>>......>>>>>>>...
>>>....<<<....>>><<<<<<<....>>>>>>>.<<<<<<<<<.....
....>>>>>>>>>.>>...<<<<<<...................>>>>>.
>.........<<....>>..<<<<<<.....<<.....>>....>>>>>>
..<<<..<<<<......<<<<.<<<<<<<<.<<<...<<<<<......>>
>>>((......<<<.....))>>>...>>>...>>>>>>>>.>>>>...>
>>>........<<<.<<<<.........>>>>.>>>......<<<<<..>
>>>>..>>>......>>.>>>>>>>.>>...............<<....>
>....>>.........<<<<.....>>>>.............>....>>>
>>>>>>>>.......<<<<..<<<<<<....>>>>>>..>>>>.<<<<<<
....<<<<<<<<<<<<<..<<<...<<.....>>...>>>...<<....>
>..<<<......>.>>.....>>>>>>>>>>>>>..<<.<..<<<<<<<.
.>>>>>>...>..>.>>..<<<<<<....<<<<<....>>>>>.<<<<<<
<<...<<<<<<<...>>>>>.>>...>>>>>>>.>...<<<<<<<<....
......>>>>>>>>....<<<......>>>...<<<<.<<<...<<<(((
.....<<<<<<....))).....>>>>>>.>>>...>>>>>>><<<<<<<
<<....>>>>>>>>>....>>>>>><<<<<<<...<<<......<<<<<<
<<....>>>>>>>>...>>>..>>>>>.>>.....>>>>>>..<<<<<<.
..<<.....>>.>>>>>>....<<((..<<<<<........>>>>>>><<
<<<.>>>>>..)).....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8c98 Cryo-EM captures early ribosome assembly in action.
Resolution3.66 Å
Binding residue
(original residue number in PDB)		N4 S7 P8 G11 S12 K13 K14 K17 R18 L19 G20 R21 G22 I23 G24 S25 L27 E76 R78 D81 K109 I111 L112 A113 T128 K129 G130 A131
Binding residue
(residue number reindexed from 1)		N3 S6 P7 G10 S11 K12 K13 K16 R17 L18 G19 R20 G21 I22 G23 S24 L26 E33 R35 D38 K66 I68 L69 A70 T85 K86 G87 A88
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0019843 rRNA binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8c98, PDBe:8c98, PDBj:8c98
PDBsum8c98
PubMed36797249
UniProtP02413|RL15_ECOLI Large ribosomal subunit protein uL15 (Gene Name=rplO)

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