Structure of PDB 8c96 Chain L Binding Site BS01

Receptor Information
>8c96 Chain L (length=109) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RLNTLSPAEGSKKAGKRLGRGIGSGLGKTGGRGHKAAITAEIRLSDLAKV
EGGVVDLNTLKAANIIGIQIEFAKVILAGEVTTPVTVRGLRVTKGARAAI
EAAGGKIEE
Ligand information
>8c96 Chain A (length=1475) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gguuaagcgacuaagcguacacgguggaugcccuggcagucagaggcgau
gaaggacgugcuaaucugcgauaagcgucgguaaggugauaugaaccguu
auaaccggcgauuuccgaauggggaaacccaguguguuucgacacacuau
cauuaacugaauccauagguuaaugaggcgaaccgggggaacugaaacau
cuaaguaccccgaggaaaagaaaucaaccgagauucccccaguagcggcg
agcgaacggggagcagcccagagccugaaucaguguguguguuaguggaa
gcgucuggaaaggcgcgcgauacagggugacagccccguacacaaaaaug
cacaugcugugagcucgaugaguagggcgggacacgugguauccugucug
aauauggggggaccauccuccaaggcuaaauacuccugacugaccgauag
ugaaccaguaccgugagggaaaggcgaaaagaaccccggcgaggggagug
aaaaagaaccugaaaccguguacguacaagcagugggagcacgcuuaggc
gugugacugcguaccuuuuguauaaugggucagcgacuuauauucuguag
caagguuaaccgaauaggggagccgaagggaaaccgagucuuaacugggc
guuaaguugcaggguauagacccgaaacccggugaccgggagauagcugg
uucuccccgaaagcuauuuagguagcgccucgugaauucaucuccggggg
uagaugcgaauaccggagaauguuaucacgggagacacacggcgggugcu
aacguccgucgugaagagggaaacaacccagaccgccagcuaagguccca
aagucaugguuaagugggaaacgcggaagauguaacggggcuaaaccaug
caccgaagcugcggcagcgacgcuuaugcguuguuggguaggggagcguu
cuguaagccugcgaaggugugcugugaggcaugcuggagguaucagaagu
gcgaaugcugacauaaguaacgauaaagcgggugaaaagcccgcucgccg
gaagaccaaggcgacgguugggucagguagagaauaccaaggcgcuugag
agaacucgggugaaggaaaggcugucuccacccgagacucagugaaauug
aacucgcugugaagaugcaguguacccgcggcaagaucugccgugggcgc
uggagaacugaggggggcugcuccuaguacgagaggaccggaguggacgc
aucacugguguucggguugucaugccaauggcacugcccgguagcuaaau
gcggaagagauaagugcugaaagcaucuaagcacgaaacuugccccgaga
ugaguucucccugacccuuuaaggguccugaaggaacguugaagacgacg
acguugauaggccggguguguaagcgcagcgaugcguugagcuaaccggu
acuaaugaaccgugaggcuuaaccu
<<<<<<<<......<<<<<<<<<<<....<<<..<<<<<<<<<<<<<...
...<<<<<<....(((.>>>.....<<<<<<<..<<<)))....>>>...
...>>>>>>>...>>>....<<<....>>><<<<<<<....>>>>>>>.<
<<<<<<<<.........>>>>>>>>>.>>....<<<<<.....<<....>
>......>>>>>...........<<....>>..<<<<<<.....<<....
.>>....>>>>>>..<<<..<<<<......<<<<<<<<<<<<<.<<<...
<<<<<......>>>>>((......<<<.....))>>>...>>>...>>>>
>>>>>>>>>...>>>>........<<<.<<<<.........>>>>.>>>.
.....<<<<<......>>>>>..>>>......>>.>>>>>>>.>>.....
..........<<....>>....>>.........<<<<.....>>>>....
.........>....>>>>>>>>>>>.......<<<<..<<<<<......>
>>>>..>>>>...<.<........>.>.<<<<<<....<<<<<<<<<<<<
<..<<<...<<.....>>...>>>....<<...>>..<<<<.....>>>>
.....>>>>>>>>>>>>>..<<.<...<<<<<<.>>>>>>......>.>>
..<<<<<<....<<<<<....>>>>>..<<<<<<<...<<<<<<<<<...
..<...>.....>>>>>>.>>>...>>>>>>>.....<<<<<<<<<<...
...>>>>>>>>>>....<<<......>>>...<<<<.<<<...<<<(((.
....<<<<<<...........<..>...........))).....>>>>>>
.>>>...>>>>>>><<<<<<<<<....>>>>>>>>>....>>>>>><<<<
<<<...<<<......<<<<<<<<....>>>>>>>>...>>>..>>>>>.>
>.....>>>>>><......<<.....<<<<<<.......>>>>>><<<<.
...<<<<........((...>>>>.<<<<.....>>>>..>>>>..<<<<
....<<<<<<<<................>>>>>>>>.>>>>>>.....>.
....<<<<<........>>>>>..<<<<<<<<.<<..>>>>>>>>>>...
.<<<<<<<...<<<<..<<<<<<.................>>>>>>.<<<
<<...<<<<...<<<<<<<<<<<.)).>>>>>>..>>>>>...>>>>.>>
>>>...<<<....<<<<<...........>>>>>....>>>.>>>>....
...>>>>>>>..<<<<<.....>>>>>.....<<..<<<<<.......>>
>>>....<<<<<<<<..<<....<<<<<....>>>>>...>>...>>>>>
.>>>.....>>.....>>>>>>>>.
Receptor-Ligand Complex Structure
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PDB8c96 Cryo-EM captures early ribosome assembly in action.
Resolution4.43 Å
Binding residue
(original residue number in PDB)		N4 S7 P8 G11 S12 K13 K17 R18 L19 G20 R21 G22 I23 G24 S25 K29 T30 G32 R33 G34 H35 K70 E76 R78 K109 I111 L112 A113 T128 K129 G130
Binding residue
(residue number reindexed from 1)		N3 S6 P7 G10 S11 K12 K16 R17 L18 G19 R20 G21 I22 G23 S24 K28 T29 G31 R32 G33 H34 K35 E41 R43 K74 I76 L77 A78 T93 K94 G95
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0019843 rRNA binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8c96, PDBe:8c96, PDBj:8c96
PDBsum8c96
PubMed36797249
UniProtP02413|RL15_ECOLI Large ribosomal subunit protein uL15 (Gene Name=rplO)

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