Structure of PDB 8bwf Chain L Binding Site BS01

Receptor Information
>8bwf Chain L (length=77) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SRVIHIRKLPIDVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEMNTEEAA
NTMVNYYTSVTPVLRGQPIYIQFSNHK
Ligand information
Receptor-Ligand Complex Structure
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PDB8bwf Rationally designed stapled peptides allosterically inhibit PTBP1-RNA-binding.
Resolution2.9 Å
Binding residue
(original residue number in PDB)
T71 G73
Binding residue
(residue number reindexed from 1)
T14 G16
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:8bwf, PDBe:8bwf, PDBj:8bwf
PDBsum8bwf
PubMed37564416
UniProtP26599|PTBP1_HUMAN Polypyrimidine tract-binding protein 1 (Gene Name=PTBP1)

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