Structure of PDB 8bep Chain L Binding Site BS01

Receptor Information
>8bep Chain L (length=487) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SPPPPHLMPYDHAAEIIKNKIKKLENPDKRFLKYASPHPILASHNHILSA
PETRVTTLPNGLRVATESNLSAKTATVGVWIDAGSRFESDETNGTAHFLE
HMIFKGTDRRTVRALEEEIEDIGGHLNAYTSREQTTYYAKVLDSNVNQAL
DVLADILQNSKFEEQRINRERDVILREMQEVEGQTDEVVLDHLHATAFQY
TPLGRTILGPAQNVKSITREDLQNYIKTHYTASRMVIAAAGAVKHEEVVE
QVKKLFTKLSSDPTTTSQLVANEPASFTGSEVRMIDDDLPLAQFAVAFEG
ASWTDPDSVALMVMQTMLGSWNKNVGGGKHVGSDLTQRVAINEIAESIMA
FNTNYKDTGLFGVYAVAKADCLDDLSYAIMYEVTKLAYRVSDADVTRARN
QLKSSLLLHMDGTSPIAEDIGRQLLTYGRRIPTAELFARIDAVDASTVKR
VANKYIYDKDIAISAIGPIQDLPDYNKFRRRTYWNRY
Ligand information
>8bep Chain N (length=16) Species: 3702 (Arabidopsis thaliana) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
VPATVEAVKTPNSKIV
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8bep Cryo-EM structure of the respiratory I + III 2 supercomplex from Arabidopsis thaliana at 2 angstrom resolution.
Resolution2.29 Å
Binding residue
(original residue number in PDB)		E226 H236 Q243 Y244 G248 T250 M328
Binding residue
(residue number reindexed from 1)		E182 H192 Q199 Y200 G204 T206 M284
Enzymatic activity
Enzyme Commision number 3.4.24.64: mitochondrial processing peptidase.
Gene Ontology
Molecular Function
GO:0004222 metalloendopeptidase activity
GO:0005515 protein binding
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0000325 plant-type vacuole
GO:0005730 nucleolus
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0005743 mitochondrial inner membrane
GO:0005758 mitochondrial intermembrane space
GO:0005759 mitochondrial matrix
GO:0005829 cytosol
GO:0009505 plant-type cell wall
GO:0009507 chloroplast

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8bep, PDBe:8bep, PDBj:8bep
PDBsum8bep
PubMed36585502
UniProtQ42290|MPPB_ARATH Probable mitochondrial-processing peptidase subunit beta, mitochondrial (Gene Name=MPPbeta)

[Back to BioLiP]