Structure of PDB 8b0j Chain L Binding Site BS01

Receptor Information
>8b0j Chain L (length=481) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KRMLINATQQEELRVALVDGQRLYDLDIESPGHEQKKANIYKGKITRIEP
SLEAAFVDYGAERHGFLPLKEIAREYFPANYSAHGRPNIKDVLREGQEVI
VQIDKEERGNKGAALTTFISLAGSYLVLMPNNPRAGGISRRIEGDDRTEL
KEALASLELPEGMGLIVRTAGVGKSAEALQWDLSFRLKHWEAIKKAAESR
PAPFLIHQESNVIVRAFRDYLRQDIGEILIDNPKVLELARQHIAALGRPD
FSSKIKLYTGEIPLFSHYQIESQIESAFQREVRLPSGGSIVIDSTEALTA
IDINSARATRGGDIEETAFNTNLEAADEIARQLRLRDLGGLIVICFIDMT
PVRHQRAVENRLREAVRQDRARIQISHISRFGLLEMSRQRLSPSSSHHVC
PRCSGTGTVRDNESLSLSILRLIEEEALKENTQEVHAIVPVPIASYLLNE
KRSAVNAIETRQDGVETPHYHVLRVRLSYML
Ligand information
>8b0j Chain K (length=160) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcucauuccaucucuuauguucgccuuagugccucauaaacuccggaaug
acgcagagggugcuuaucguccacugacagucgcuuucaucagaugacac
aacguugagugaagcacccacuuguaacgccugcuccguuaauaagagca
ggcguuuuuu
..<<<<<<......<<<<<...<........>..>>>>>......>>>>>
>.......<<<<<<<...<<<........................>>>..
...........>>>>>>>.......<<<<....<..<.<<...>>>.>..
..>>>>....
Receptor-Ligand Complex Structure
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PDB8b0j Structure of a bacterial ribonucleoprotein complex central to the control of cell envelope biogenesis.
Resolution3.99 Å
Binding residue
(original residue number in PDB)		R3 G21 Q22 S52 L53 F67 K112 G113 G137 G138 I139 S140 E144 I167 I263 H268 Y269 R354 R357 R373 H378
Binding residue
(residue number reindexed from 1)		R2 G20 Q21 S51 L52 F66 K111 G112 G136 G137 I138 S139 E143 I166 I262 H267 Y268 R353 R356 R372 H377
Enzymatic activity
Enzyme Commision number 3.1.26.12: ribonuclease E.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0004540 RNA nuclease activity
GO:0008995 ribonuclease E activity
Biological Process
GO:0006396 RNA processing

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Molecular Function
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Biological Process
External links
PDB RCSB:8b0j, PDBe:8b0j, PDBj:8b0j
PDBsum8b0j
PubMed36504162
UniProtP21513|RNE_ECOLI Ribonuclease E (Gene Name=rne)

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