Structure of PDB 7r5s Chain L Binding Site BS01

Receptor Information
>7r5s Chain L (length=312) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PLQKRLESVRKQSSFILTPPRRKIPQCSQLQEDVDPQKVAFLLHKQWTLY
SLTPLYKFSYSNLKEYSRLLNAFIVAEKQKGLAVEVGEDFNIKVIFSTLL
GMKGTQRDPEAFLVQIVSKSEGKVLWTGWFCCVFGDSLLETVSEDFTCLP
LFLANGAESNTAIIGTWFQKTFDCYFSPLAINAFNLSWMAAMWTACKMDH
YVATTEFLWSVPCSPQSLDISFAIHPEDAKALWDSVHKTPGEVTQEEVDL
FMDCLYSHFHRHFKIHLSATRLVRVSTSVASAHTDGKIKILCHKYLIGVL
AYLTELAIFQIE
Ligand information
>7r5s Chain i (length=41) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ccgtttccaacgaaggcctcaaagcggtccaaatatccact
Receptor-Ligand Complex Structure
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PDB7r5s Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome.
Resolution2.83 Å
Binding residue
(original residue number in PDB)		E190 S191
Binding residue
(residue number reindexed from 1)		E158 S159
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
Biological Process
GO:0007059 chromosome segregation
Cellular Component
GO:0000775 chromosome, centromeric region
GO:0000939 inner kinetochore
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7r5s, PDBe:7r5s, PDBj:7r5s
PDBsum7r5s
PubMed35420891
UniProtQ8N0S6|CENPL_HUMAN Centromere protein L (Gene Name=CENPL)

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