Structure of PDB 7pu5 Chain L Binding Site BS01

Receptor Information
>7pu5 Chain L (length=240) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EKTYTQRCRLFVGNLPADITEDEFKRLFAKYGEPGEVFINKGKGFGFIKL
ESRALAEIAKAELDDTPMRGRQLRVRFATHAAALSVRNLSPYVSNELLEE
AFSQFGPIERAVVIVDDRGRSTGKGIVEFASKPAARKAFERCSEGVFLLT
TTPRPVIVEPLEQLDDEDGLPEKLAQKNPMYQKERETPPRFAQHGTFEYE
YSQRWKSLDEMEKQQREQVEKNMKDAKDKLESEMEDAYHE
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain7pu5 Chain L Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7pu5 Crystal structure of SFPQ-NONO heterodimer.
Resolution2.999 Å
Binding residue
(original residue number in PDB)		D353 D457
Binding residue
(residue number reindexed from 1)		D64 D168
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:7pu5, PDBe:7pu5, PDBj:7pu5
PDBsum7pu5
PubMed35245601
UniProtP23246|SFPQ_HUMAN Splicing factor, proline- and glutamine-rich (Gene Name=SFPQ)

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