Structure of PDB 7ohp Chain L Binding Site BS01

Receptor Information
>7ohp Chain L (length=108) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VKVHFDQAGKKVSRRNARATRAAKIAPRPLDLLRPVVRAPTVKYNRKVRA
GRGFTLAEVKAAGLTAAYARTIGIAVDHRRQNRNQEIFDANVQRLKEYQS
KIIVFPRN
Ligand information
>7ohp Chain 1 (length=1567) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guuugaccucaaaucagguaggaguacccgcugaacucaauaagcggagg
aaaagaaaccaaccgggauugccuuaguaacgcgagugaagcggcaaaag
cucaaauuugaaaucugguaccucggugcccgaguuguaauuuggagagg
gcaacuuuggggccguuccuugucuauguuccuuggaacaggacgucaua
gagggugagaaucccguguggcgaggagugcgguucuuuguaaagugccu
ucgaagagucgaguuguuuaugcagcucuaagugggugguuccaucuaaa
gcuaaauauuggcgagagaccgauagcgaacaguacagugauggaaagau
gaaaagaacuuugagagagugaaaaaguacgugaaauuguugaaaggaag
ggcauuugaucagacaugguguuuuguucucgcauuucacugggccagca
ucaguuuugguggcaggauaaauccauaggaauguagcuugccgguaagu
auuauagccugugggaauacugccagcugggacugaggacugcgacguaa
gucaaggaugcuggcaaaugguuauaugccgccgucuugaaacacggacc
aaggagucuaacgucuaugcgaguguuuggguguaaaacccauacgcgua
augaacgagguuggggccucgaagaggugcacaaucgaccgauccugagg
auggauuugguaagagcauagcuguugggacccgaaagauggugaaacca
ucuaguacugguuccugccgaaguuucccucaggauagcagaagcucguu
caguuuuauguaagaaugaagcuuuuagugggccauuuuugggcagaacu
ggcgaugcgggaugccgaacguagaguuaaggugccggaauacacgcuca
agacaaaagguguuaguucaucuagacagccggacggugccauggaaguc
ggaaccgcaggaguguguaacaacucaccggccgaaugaacuagcccugg
gcgcucaagcguguuaccuauacucuaccgucaggguugauaugcccuga
cgaguaggcaggcguggaggucagugacgaagccuagaccguaaggucgg
gucgaacggccucuagugcagaucuuggugguaguagcagcgaaaccaca
gccaaggcgggaaucagcauaccgaagcagaauucgguaagaugaauguu
accgcaauaguaauugaacuuaguacgagaggaacaguucauucggauaa
uugguuugcggcugucugaucaggcagccgcgaagcuacauccgcuggau
uauggcugaacccucuaagucagauccaugcuagaacgcggugauuucuu
ugcuccacacaauauagauggauacgaauaaggcguccuuguggcgucgc
ugaaccauagcaggcuagcaacggugcacuuggcggaaaggccuugggug
cuugcuggcgaauugcaaugucauuuugcguggggauaaaucauuuguau
acgacuuagauguacaacgggguauuguaagcaguacugcugagauuacc
uuuguugucugauuugu
..........................<<<<<<..........>>>>>.>.
........<<....>>...<<<<......<<....>>.....>>>>...<
<<...........<<.<<<<<<..>>>>>>.>>.............<<<<
<<<.<<<<<<<<<<<<<<<<<<<<<....<<<<......>>>>.((....
..<<<.....))>>>..>.>>>>>>>>..>>>>>>>>....>>>>>>>>>
>>........<<<<<<<....>>>>>>>.....<<<<<<..>>>>>>..>
>>.................................<<....>>.......
........<<<...>>>.................................
<<<<.<<<<<<..............<......>..........<<<<<<<
.<<<<<<<<<<<<<<<.....<<<<<<<<<......<<<........>>>
.......>>>>>>>>..>.>>>>>.>>>>>>>>>>........<<<....
>>>.....>>>>>>>....>>>>>.>>>>>.<<<<........>>>><<<
<<<....<<<<<<.<<<<<<..<<<...<<<<.....>>>>...>>>...
........<<<<<..<<<<<...>>>>>...>>>>>.<<<..<<<.....
..>>>...>>>....>>>>>>.>>>>>>..<<.<..<<<<<<<...>>>>
>>>....>.>>..<<<<<<......<.......>...<<<<<<<<<...<
<<.<<.........>>>>>>>>>>>>.>>..<<<<....<<..>>....>
>>>....<<<....>>>...<<<<<<<..<<<<(((.....<<<<<<...
<<.....<<<.<<<<<<<<<........<<<<<.<<<..<<.........
>>..>>>.......<<......>>...>>>>>....>>>>>>>>>>>>.)
)).>>...>>>>>>.>>>>..>>>>>>><<<<<<<<<......>>>>>>>
>>....>>>>>><..<<<<<<<.<<......<<<<.<<<<....>>>>>>
>>...>>>>>>>>>...>.....>>>>>><<..............>>...
............<<<.....<<<<<<......>>>>>>..>>>....<.<
<<<<<..<<<<.<.<<<<<<...............>>>>>>.><<<<<..
.<<....<<<<<<<<........>>>>>>>>.....>>.>>>>>.<<<<.
..<<<<<..........>>>>>..>>>>.>>>>....>>>>>>.>.....
.<<<<<<<.<<<.<<....<<..........<<<<<<.....>>>>>>..
....>>.......<<<<<<...<<<<<.<..<<<......>>>..>.>>>
>>.>>>>>>.............>>.>>>.>>>>>>.><<<<<........
.............<<<<<.<<<.<<<....<<......>>...>>>..>>
>..>>>>>..>>>>>..
Receptor-Ligand Complex Structure
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PDB7ohp Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors.
Resolution3.9 Å
Binding residue
(original residue number in PDB)
Q28 K32 R35 R36 R39 R42 L53 R55 V58 R59 T62 V63 Y65 N66 K68 R70 G72 R73 R91 D98 H99 R100 R101 R104 N105 R128
Binding residue
(residue number reindexed from 1)
Q7 K11 R14 R15 R18 R21 L32 R34 V37 R38 T41 V42 Y44 N45 K47 R49 G51 R52 R70 D77 H78 R79 R80 R83 N84 R107
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7ohp, PDBe:7ohp, PDBj:7ohp
PDBsum7ohp
PubMed34813592
UniProtQ12690|RL13A_YEAST Large ribosomal subunit protein eL13A (Gene Name=RPL13A)

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