Structure of PDB 7o3e Chain L Binding Site BS01

Receptor Information

>7o3e Chain L (length=445) Species: 10090 (Mus musculus)

ATFAQALQSVPETQVSILDNGLRVASEQSSHATCTVGVWIDAGSRYETEK
NNGAGYFLEHLAFKGTKNRPGNALEKEVESIGAHLNAYSTREHTAYLIKA
LSKDLPKVVELLADIVQNSSLEDSQIEKERDVILREMQENDASMQNVVFD
YLHATAFQGTPLAQAVEGPSENVRRLSRTDLTDYLNRHYKAPRMVLAAAG
GVEHQQLLDLAQKHLSSVSRVYEEDAVPGLTPCRFTGSEIRHRDDALPLA
HVAIAVEGPGWANPDNVTLQVANAIIGHYDCTYGGGVHLSSPLASVAVAN
KLCQSFQTFNISYSDTGLLGAHFVCDAMSIDDMVFFLQGQWMRLCTSATE
SEVTRGKNILRNALVSHLDGTTPVCEDIGRSLLTYGRRIPLAEWESRIQE
VDAQMLRDICSKYFYDQCPAVAGYGPIEQLPDYNRIRSGMFWLRF

Ligand information

>7o3e Chain P (length=15) Species: 10090 (Mus musculus)

SHTDVKVPDFSDYRR

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7o3e Structure and assembly of the mammalian mitochondrial supercomplex CIII 2 CIV.
• Resolution: 3.6 Å
• Binding residue (original residue number in PDB): M138 D142 V148 D151 Q159 G169 P170 S171 E172 R235
• Binding residue (residue number reindexed from 1): M137 D141 V147 D150 Q158 G168 P169 S170 E171 R234

Gene Ontology

Molecular Function

• GO:0005515 protein binding
• GO:0031625 ubiquitin protein ligase binding
• GO:0044877 protein-containing complex binding
• GO:0046872 metal ion binding

Biological Process

• GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c
• GO:0014823 response to activity
• GO:0034551 mitochondrial respiratory chain complex III assembly
• GO:0043279 response to alkaloid
• GO:0045333 cellular respiration

Cellular Component

• GO:0005739 mitochondrion
• GO:0005743 mitochondrial inner membrane
• GO:0043209 myelin sheath
• GO:0045275 respiratory chain complex III

External links

• PDB: RCSB:7o3e, PDBe:7o3e, PDBj:7o3e
• PDBsum: 7o3e
• PubMed: 34616041
• UniProt: Q9CZ13|QCR1_MOUSE Cytochrome b-c1 complex subunit 1, mitochondrial (Gene Name=Uqcrc1)