Structure of PDB 7c79 Chain L Binding Site BS01

Receptor Information
>7c79 Chain L (length=131) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EMDNVIRSLEQEYRLILLLNHRNKNQHRAASWYGSFNEMKRNCGQIITLF
SSRRLQAKRLKDVEWVKLHRLLQRALFRQLKRWYWQFNGVIALGQFVTLG
CTLVTLLANVRALYMRLWEINETEFIRCGCL
Ligand information
>7c79 Chain A (length=331) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aauccaugaccaaagaaucgucacaaaucgaagcuuacaaaauggaguaa
aauuuuguuuacucaguaauaugcuuuggguugaaagucucccaccaauu
cguaugcggaaaacguaaugagauuuaaaaauaauuguuuaaaucaacuc
auuaaggaggaugcccuuggguauucugcuucuugaccugguaccucuau
ugcaggguacugguguuuucuucgguacuggauuccguuuguauggaauc
uaaaccauaguuaugacgauugcucuuucccgugcuggaucgaguaaccc
aauggagcuuacuauucuugguccauggauu
<<<<<<<<<<<<<<.<<<<<<<......<<<<<<..........<<<<<<
<......>>>>>>>........>>>>>>[.......{.((((.<<<....
.....<<<.....>>><<<<.<..........................>>
>>><<<.<<<<<<<<....>>>>>>>>.>>>......<<<<<<<<<....
....>>>>>>>>>..........>>>...<<<<<<<<......>>>>>>>
>.............>>>>>>><<<<..<<<......>>>..>>>>...].
...)))).}...>....>>>>>>.>>>>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7c79 Structural insight into precursor ribosomal RNA processing by ribonuclease MRP.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		H23 R24 K26 N27 R30 E40 R43 Q47 R80 Q81 W87
Binding residue
(residue number reindexed from 1)		H21 R22 K24 N25 R28 E38 R41 Q45 R78 Q79 W85
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0042134 rRNA primary transcript binding
Biological Process
GO:0000294 nuclear-transcribed mRNA catabolic process, RNase MRP-dependent
GO:0000460 maturation of 5.8S rRNA
GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
Cellular Component
GO:0000172 ribonuclease MRP complex
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7c79, PDBe:7c79, PDBj:7c79
PDBsum7c79
PubMed32586950
UniProtQ12530|RMP1_YEAST Ribonuclease MRP protein subunit RMP1 (Gene Name=RMP1)

[Back to BioLiP]