Structure of PDB 7a1f Chain L Binding Site BS01

Receptor Information
>7a1f Chain L (length=335) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNGVLIPHTPIAVDFWSLRRAGTARLFFLSHMHSDHTVGLSSTWARPLYC
SPITAHLLHRHLQVSKQWIQALEVGESHVLPLDEIGQETMTVTLLDANHC
PGSVMFLFEGYFGTILYTGDFRYTPSMLKEPALTLGKQIHTLYLDNTNCN
PALVLPSRQEAAHQIVQLIRKHPQHNIKIGLYSLGKESLLEQLALEFQTW
VVLSPRRLELVQLLGLADVFTVEEKAGRIHAVDHMEICHSNMLRWNQTHP
TIAILPTSRKIHSSHPDIHVIPYSDHSSYSELRAFVAALKPCQVVPIVSR
RPCGGFQDSLSPRISVPLIPDSVQQYMSSSSRKPS
Ligand information
Ligand IDFE
InChIInChI=1S/Fe/q+3
InChIKeyVTLYFUHAOXGGBS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Fe+3]
FormulaFe
NameFE (III) ION
ChEMBL
DrugBankDB13949
ZINC
PDB chain7a1f Chain L Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7a1f A phosphate binding pocket is a key determinant of exo- versus endo-nucleolytic activity in the SNM1 nuclease family.
Resolution1.8 Å
Binding residue
(original residue number in PDB)		D35 H36 D120
Binding residue
(residue number reindexed from 1)		D35 H36 D120
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.-.-
3.5.2.6: beta-lactamase.
External links
PDB RCSB:7a1f, PDBe:7a1f, PDBj:7a1f
PDBsum7a1f
PubMed34387694
UniProtQ9H816|DCR1B_HUMAN 5' exonuclease Apollo (Gene Name=DCLRE1B)

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