Structure of PDB 6w6v Chain L Binding Site BS01

Receptor Information
>6w6v Chain L (length=121) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDEMDNVIRSLEQEYRLILLLNHRNKNQHRAASWYGSFNEMKRNCGQIIT
LFSRLKDVEWVKLHRLLQRALFRQLKRWYWQFNGVIALGQFVTLGCTLVT
LLANVRALYMRLWEINETEFI
Ligand information
>6w6v Chain A (length=294) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auccaugaccaaagaaucgucacaaaucgaagcuuacaaaauggaguaaa
auuuuacucaguaauaugcuuuggguugaaagucucccaccaauucguau
gcggaaaacguaaugagauuuaaaaauaaaucaacucauuaaggaggaug
ccgguauucugcuucuugaccugguaccucuaggguacugguguucggua
cuggauuccgauggaaucuaaaccauaguuaugacgauugcucuuuccug
gaucgaguaacccaauggagcuuacuauucuugguccauggauu
<<<<<<<<<<<<<.<<<<<<<......<<<<<<..........<<<<<<<
..>>>>>>>........>>>>>>{......[[.((((.<<<.........
<<<.....>>><<<<<<.................>>>>>>.<<.<<<<<<
<<>>>>>>>>.>>.......<<<<<<<<.<<>>>>>>>>>>.....>>>.
..<<<<<<<...>>>>>>>.............>>>>>>><<<<..<<<.>
>>..>>>>...}....))))]]...>....>>>>>>.>>>>>>.
Receptor-Ligand Complex Structure
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PDB6w6v Cryo-EM structure of catalytic ribonucleoprotein complex RNase MRP.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		R24 N27 G36 N39 E40 K42 R43 R80 Q81 R84 W87
Binding residue
(residue number reindexed from 1)		R24 N27 G36 N39 E40 K42 R43 R73 Q74 R77 W80
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0042134 rRNA primary transcript binding
Biological Process
GO:0000294 nuclear-transcribed mRNA catabolic process, RNase MRP-dependent
GO:0000460 maturation of 5.8S rRNA
GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
Cellular Component
GO:0000172 ribonuclease MRP complex
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6w6v, PDBe:6w6v, PDBj:6w6v
PDBsum6w6v
PubMed32651392
UniProtQ12530|RMP1_YEAST Ribonuclease MRP protein subunit RMP1 (Gene Name=RMP1)

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