Structure of PDB 6nf8 Chain L Binding Site BS01

Receptor Information
>6nf8 Chain L (length=109) Species: 9913 (Bos taurus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ATLNQLHRRGPPKFPPSKPGPTEGRPQLKGVVLRTFIRKPKKPNSANRKC
CRVRLSTGREAVCFIPGEGHNLQEHHVVLVQGGRTQDLPGVKLKVVRGKY
DCGHVQKKK
Ligand information
>6nf8 Chain A (length=952) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
agguuuggucccagccuuccuguuaacucuuaauaaacuuacacaugcaa
gcaucuacaccccagugagaaugcccucuagguuauuaaaacuaagagga
gcuggcaucaagcacacacccuguagcucacgacgccuugcuuaaccaca
ccccacgggaaacagcagugacaaaaauuaagccauaaacgaaaguuuga
cuaaguuauauuaauuaggguugguaaaucucgugccagccaccgcgguc
auacgauuaacccaagcuaacaggaguacggcguaaaacguguuaaagca
ccauaccaaauaggguuaaauucuaacuaagcuguaaaaagccaugauua
aaauaaaaauaaaugacgaaagugacccuacaauagccgacgcacuauag
cuaagacccaaacugggauuagauaccccacuaugcuuagcccuaaacac
agauaauuacauaaacaaaauuauucgccagaguacuacuagcaacagcu
uaaaacucaaaggacuuggcggugcuuuauauccuucuagaggagccugu
ucuauaaucgauaaaccccgauaaaccucaccaauucuugcuaauacagu
cuauauaccgccaucuucagcaaacccuaaaaaggaaaaaaaguaagcgu
aauuaugauacauaaaaacguuaggucaagguguaaccuaugaaauggga
agaaaugggcuacauucucuacaccaagagaaucaagcacgaaaguuauu
augaaaccaauaaccaaaggaggauuuagcaguaaacuaagaauagagug
cuuaguugaauuaggccaugaagcacgcacacaccgcccgucacccuccu
caaauagauucagugcaucuaacccuauuuaaacgcacuagcuacaugag
aggagacaagucguaacaagguaagcauacuggaaagugugcuuggauaa
au
<<<.<.....[[.>.>>><<<<<<<.<...<<<<<<<..<.<<<.<<<..
...............<......<<<<<<<.<<<<.....>>>>.>>>>>.
>>.<<<....<<<..<<<...>>>.>>>......>>>..<.....>.>..
<<.....>>.....>>>>>>>.........<<....<<<<....>>>>..
>>...>>.>>>>>....<<<<<<<<.....(((.....((.>>>))....
...)))..>>>>>..>.>>>>>>>.....<<.((.....<<<<....<..
..........<<<<<<.......<<<.<<.<<<......>>>..>>.>>>
................<....>..>>>>>>......>....>>>>...<<
<<<<<...<<...<<<<.........>>>>...>>>>>>>>..>......
.<<<<<<<......))..>>>>>>>..>>.<<<.......<<<....>>>
.....>>>...]]...<<<<<.<<<<<<....<<..<<<<<...<<<<<<
<<......<<........>>..........<<<.<<<...........<<
.<<<...<<<<<.......<<..<<<<<....>>>.......>>..>>..
....<<.....>>..........>>>...>>.>>>>>....>>>.>>>..
.>.>>>>>>>......<<<<......>>>>.........<....<<<<<<
........>>>>>>....>.....>>>>>.....<<<<<<<.........
>>>>>>>......>>....>>>>>>>>>.>>.......<<.<...<<<<<
<.............<<....<........>....>>.............>
>>>>>....>.>>.........<<<<<<<<<....>>>>>>>>>......
..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6nf8 Structure of Human Mitochondrial Translation Initiation Factor 3 Bound to the Small Ribosomal Subunit.
Resolution3.48 Å
Binding residue
(original residue number in PDB)		A31 T32 N34 Q35 R38 F44 K48 G54 R55 P56 Q57 K59 K72 N74 S75 N77 G97 E98 G112 Q116 D117 K124 G128 K129 H134 K138 K139
Binding residue
(residue number reindexed from 1)		A1 T2 N4 Q5 R8 F14 K18 G24 R25 P26 Q27 K29 K42 N44 S45 N47 G67 E68 G82 Q86 D87 K94 G98 K99 H104 K108 K109
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005763 mitochondrial small ribosomal subunit
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6nf8, PDBe:6nf8, PDBj:6nf8
PDBsum6nf8
PubMed30677741
UniProtQ29RU1|RT12_BOVIN Small ribosomal subunit protein uS12m (Gene Name=MRPS12)

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