Structure of PDB 6mwn Chain L Binding Site BS01
Receptor Information
>6mwn Chain L (length=213) Species:
9606
(Homo sapiens) [
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DIQMTQSPSSLSASVGDRVTITCRASQSVYYSVAWYQQKPGKAPKLLIYS
ASYLYSGVPSRFSGSRSGTDFTLTISSLQPEDFATYYCQQYRRRPITFGQ
GTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKV
DNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQG
LSSPVTKSFNRGE
Ligand information
>6mwn Chain A (length=92) [
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ggcaaacaucauuuggccuuaaaugggauucugugagaggggaucccucc
auugacagcuggacuguucuuuggggccuuaugugguguuug
..<<<<<<<<<<..<<<<......<<<<<<<<.......>>>>>>>>.<<
<..<<<<.......>>.>>..>>>>>>>....>>>>>>>>>>
Receptor-Ligand Complex Structure
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PDB
6mwn
A conserved RNA structural motif for organizing topology within picornaviral internal ribosome entry sites.
Resolution
2.838 Å
Binding residue
(original residue number in PDB)
Q28 S29 Y31 R67 G69 R93 R94
Binding residue
(residue number reindexed from 1)
Q27 S28 Y30 R66 G68 R92 R93
Binding affinity
PDBbind-CN
: Kd=44nM
External links
PDB
RCSB:6mwn
,
PDBe:6mwn
,
PDBj:6mwn
PDBsum
6mwn
PubMed
31399592
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