Structure of PDB 6gc7 Chain L Binding Site BS01

Receptor Information
>6gc7 Chain L (length=109) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RLNTLSPAEGSKKAGKRLGRGIGSGLGKTGGRGHKAAITAEIRLSDLAKV
EGGVVDLNTLKAANIIGIQIEFAKVILAGEVTTPVTVRGLRVTKGARAAI
EAAGGKIEE
Ligand information
>6gc7 Chain A (length=1901) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gguuaagcgacuaagcguacacgguggaugcccuggcagucagaggcgau
gaaggacgugcuaaucugcgauaagcgucgguaaggugauaugaaccguu
auaaccggcgauuuccgaauggggaaacccaguguguuucgacacacuau
cauuaacugaauccauagguuaaugaggcgaaccgggggaacugaaacau
cuaaguaccccgaggaaaagaaaucaaccgagauucccccaguagcggcg
agcgaacggggagcagcccagagccugaaucaguguguguguuaguggaa
gcgucuggaaaggcgcgcgauacagggugacagccccguacacaaaaaug
cacaugcugugagcucgaugaguagggcgggacacgugguauccugucug
aauauggggggaccauccuccaaggcuaaauacuccugacugaccgauag
ugaaccaguaccgugagggaaaggcgaaaagaaccccggcgaggggagug
aaaaagaaccugaaaccguguacguacaagcagugggagcacgcuuaggc
gugugacugcguaccuuuuguauaaugggucagcgacuuauauucuguag
caagguuaaccgaauaggggagccgaagggaaaccgagucuuaacugggc
guuaaguugcaggguauagacccgaaacccgguggugaaaggccaaucaa
accgggagauagcugguucuccccgaaagcuauuuagguagcgccucgug
aauucaucuccggggguagagcaccaaacugcgaauaccggagaauguua
ucacgggagacacacggcgggugcuaacguccgucgugaagagggaaaca
acccagaccgccagcuaaggucccaaagucaugguuaagugggaaacgcg
gaagauguaacggggcuaaaccaugcaccgaagcugcggcagcgacgcuu
augcguuguuggguaggggagcguucuguaagccugcgaaggugugcugu
gaggcaugcuggagguaucagaagugcgaaugcugacauaaguaacgaua
aagcgggugaaaagcccgcucgccggaagaccaaggguuccuguccaacg
uuaaucggggcagggugagucgaccccuaaggcgaggccgaaaggcguag
ucgaugggaaacagguuaauauuccuguacuugguguuacugcgaagggg
ggacggagaaggcuauguuggccgggcgacgguugucccgguuuaagcgu
guaggcugguuuuccaggcaaauccggaaaaucaaggcugaggcgugaug
acgaggcacuacggugcugaagcaacaaaugcccugcuuccaggaaaagc
cucuaagcaucagguaacaucaaaucguaccccaaaccgacacagguggu
cagguagagaauaccaaggcgcuugagagaacucgggugaaggaacuagg
caaaauggugccggcacgcugauauguaggugaggucccucgcggaugga
gcugaaaucagucgaagauaccagcuggcgccaggcugucuccacccgag
acucagugaaauugaacucgcugugaagaugcaguguacccgcggcaaga
cggaaaucccuaucugccgugggcgcuggagaacugaggggggcugcucc
uaguacgagaggaccggaguggacgcaucacugguguucggguugucaug
ccaauggcacugcccgguagcuaaaugcggaagagauaagugcugaaagc
aucuaagcacgaaacuugccccgagaugaguucucccugacccuuuaagg
guccugaaggaacguugaagacgacgacguugauaggccggguguguaag
cgcagcgaugcguugagcuaaccgguacuaaugaaccgugaggcuuaacc
u
<<<<<<<<......<<<<<<<<<<<....<.<<.<<<<<<<<<<<<<...
...<<<<<<....(((.>>>.....<<<<<<<..<<<)))....>>>...
...>>>>>>>...>>>....<<<....>>><<<<<<<....>>>>>>>.<
<<<<<<<<.........>>>>>>>>>.>>...<<<<<<.....<<....>
>......>>>>>.>.........<......>..<<<<<<.....<<....
.>>....>>>>>>..<<<..<<<<......<<<<<<<<<<<<<.<<<...
<<<<<......>>>>>((......<<<.....))>>>...>>>.>..>>>
>>>>>>>>>...>>>>........<<<<<<<<.........>>>>>>>>.
.....<<<<<......>>>>>..>>>......>>.>>>>>>>.>>.....
..........<<....>>....>>.........<<<.......>>>....
.........>....>>>>>>>>>>>.......<<<<..<<<<<......>
>>>>..>>>>...<.<........>.>.<<<<<<....<<<<<<<<<<<<
<..<<<...<<.....>>...>>>...<<....>>..<<<<.....>>>>
.....>>>>>>>>>>>>>..<<.<...<<<<<<.<<.....>>.......
>>>>>>......>.>>..<<<<<<....<<<<<....>>>>>..<<<<<<
<...<<<<<<<<<......<<.......>>.......>>>>>>.>>>...
>>>>>>>.....<<<<<<<<<<......>>>>>>>>>>....<<<.....
.>>>...<<<<.<<<...<<<(((.....<<<<<<...........<..>
...........))).....>>>>>>.>>>...>>>>>>><<<.<..<...
...>..>.>>>....>>>>>><<<<<<<...<<<......<<<<<<<<..
..>>>>>>>>...>>>..>>>>>.>>.....>>>>>><......<<....
.<<<<<<.......>>>>>><<<<....<<.<<.<<...<<<<<<...<<
.....>>.>>>>>>....((<<<.<<<...<<....<<<....>>>....
>>...>>>...<<<<........>>>>.))<<<<<<<<<<<<<...<<<<
....<<<<..<<<..<<<<<<<<<<<....(((...>>>>>><<..<<<<
...<<<<<<<<<<<<.<<.....>>>>>>>>>>..>>>>...>>>>...>
><..<<<<<....>>>>>...>>>>>>...>>>...>>>>.........>
>>>...>>....>>>>>>>>>>>.>>>..>>.....<<......>>>>.>
>.<<<<.....>>>>..>>>>..<<<<....<<<<<<<<.<<........
.......<<<<..>>>><<<<<......<<<...<<<<.....>>>>...
>>>....>>>>>............<<<<..>>>>.....>>.>>>>>>>>
.>>>>>>.....>.....<<<<<........>>>>>..<<<<<<<<.<<<
.<.......>..>>>>>>>>>>>....<<<<<<<...<<<<..<<<<<<<
...............>>>>>>>.<<<<<...<<<<...<<<<<<<<<<<)
)).>>>>>>..>>>>>...>>>>.>>>>>...<<<....<<<<<......
.....>>>>>....>>>.>>>>.......>>>>>>>..<<<<<.....>>
>>>.....<<..<<<<<.......>>>>>....<<<<<<<<..<<....<
<<<<....>>>>>...>>...>>>>>.>>>.....>>.....>>>>>>>>
.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6gc7 Structural Visualization of the Formation and Activation of the 50S Ribosomal Subunit during In Vitro Reconstitution.
Resolution4.3 Å
Binding residue
(original residue number in PDB)		N4 P8 G11 S12 K13 K14 G16 K17 R18 L19 G20 R21 G22 G24 L27 K29 T30 G31 G32 R33 H35 K70 A71 E76 R78 K109 I111 L112 A113 R126 T128 K129 G130
Binding residue
(residue number reindexed from 1)		N3 P7 G10 S11 K12 K13 G15 K16 R17 L18 G19 R20 G21 G23 L26 K28 T29 G30 G31 R32 H34 K35 A36 E41 R43 K74 I76 L77 A78 R91 T93 K94 G95
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0019843 rRNA binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6gc7, PDBe:6gc7, PDBj:6gc7
PDBsum6gc7
PubMed29883607
UniProtP02413|RL15_ECOLI Large ribosomal subunit protein uL15 (Gene Name=rplO)

[Back to BioLiP]