Structure of PDB 6dcw Chain L Binding Site BS01

Receptor Information
>6dcw Chain L (length=219) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DIQLTQSPDSLAVSLGERATINCKSSQSVFSRDNNKNYLAWYQHKSGQPP
KLLFFWASSRESGVSDRFSGSGSGTDFTLTIDNLQAEDVALYYCQHYFNT
PHNFGQGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREA
KVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYAC
EVTHQGLSSPVTKSFNRGE
Ligand information
Receptor-Ligand Complex Structure
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PDB6dcw A common antigenic motif recognized by naturally occurring human VH5-51/VL4-1 anti-tau antibodies with distinct functionalities.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		Y32 F92 H96
Binding residue
(residue number reindexed from 1)		Y38 F98 H102
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003823 antigen binding
Biological Process
GO:0002250 adaptive immune response
GO:0006955 immune response
GO:0016064 immunoglobulin mediated immune response
GO:0050853 B cell receptor signaling pathway
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0019814 immunoglobulin complex
GO:0070062 extracellular exosome
GO:0071735 IgG immunoglobulin complex
GO:0071738 IgD immunoglobulin complex
GO:0071742 IgE immunoglobulin complex
GO:0071745 IgA immunoglobulin complex
GO:0071753 IgM immunoglobulin complex
GO:0072562 blood microparticle

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6dcw, PDBe:6dcw, PDBj:6dcw
PDBsum6dcw
PubMed29855358
UniProtP01834|IGKC_HUMAN Immunoglobulin kappa constant (Gene Name=IGKC)

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