Structure of PDB 6b44 Chain L Binding Site BS01

Receptor Information
>6b44 Chain L (length=189) Species: 208963 (Pseudomonas aeruginosa UCBPP-PA14) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MAMDHYLDIRLRPDPEFPPAQLMSVLFGKLHQALVAQGGDRIGVSFPDLD
ESRSRLGERLRIHASADDLRALLARPWLEGLRDHLQFGEPAVVPHPTPYR
QVSRVQAKSNPERLRRRLMRRHDLSEEEARKRIPDTVARALDLPFVTLRS
QSTGQHFRLFIRHGPLQVTAEEGGFTCYGLSKGGFVPWF
Ligand information
>6b44 Chain M (length=60) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cuaagaaauucacggcgggcuugauguccgcgucuaccugguucacugcc
guguaggcag
..............................................<<<.
......>>>.
Receptor-Ligand Complex Structure
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PDB6b44 Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Resolution2.9 Å
Binding residue
(original residue number in PDB)
P16 Q19 R114 Q149 S150 G152 H154 R156
Binding residue
(residue number reindexed from 1)
P18 Q21 R116 Q151 S152 G154 H156 R158
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004519 endonuclease activity
GO:0005515 protein binding
Biological Process
GO:0043571 maintenance of CRISPR repeat elements
GO:0051607 defense response to virus

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Molecular Function

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Biological Process
External links
PDB RCSB:6b44, PDBe:6b44, PDBj:6b44
PDBsum6b44
PubMed28985564
UniProtQ02MM2|CAS6_PSEAB CRISPR-associated endonuclease Cas6/Csy4 (Gene Name=cas6f)

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