Structure of PDB 5zwm Chain L Binding Site BS01

Receptor Information
>5zwm Chain L (length=416) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EKFNPFEILPESIELFRTLALISLSETAQILPKIVDLKRILQQQEIKLLP
FFNEIIPLIKSNIKLMHNFLISLYSRRFPELSSLIPSPLQYSKVISILEN
ENYSKNESDELFFHLENKAKLTREQILVLTMSMKTSFKNKEPLDIKTRTQ
ILEANSILENLWKLQEDIGQYIASKISIIAPNVCFLVGPEIAAQLIAHAG
GVLEFSRIPSCNIASIGKNKHLSHELHTLESGVRQEGYLFASDMIQKFPV
SVHKQMLRMLCAKVSLAARVDAGQKNGDRNTVLAHKWKAELSKKARKLSE
APSISETKALPIPEDQPKKKRAGRKFRKYKEKFRLSHVRQLQNRMEFGKQ
EQTVLDSYGEEVGLGMSNTSLQQAVGATSGSRRSAGNQAKLTKVMKHRIS
EANQQADEFLISLGHN
Ligand information
>5zwm Chain F (length=99) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guucgcgaaauuuuacuucguggacauuuggucaauuugaaacaauacag
aaucagcaguuccccugcauaaggaugaaccgucaaagagauuuguuuu
<<<<<<<<<.......>>>>>>>>>.........<<<......>>>....
.................................................
Receptor-Ligand Complex Structure
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PDB5zwm Structures of the fully assembledSaccharomyces cerevisiaespliceosome before activation
Resolution3.4 Å
Binding residue
(original residue number in PDB)		K364 K366 R367 A368 G369 R370 K371
Binding residue
(residue number reindexed from 1)		K318 K320 R321 A322 G323 R324 K325
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0003723 RNA binding
Biological Process
GO:0000244 spliceosomal tri-snRNP complex assembly
GO:0000387 spliceosomal snRNP assembly
GO:0000398 mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:0008380 RNA splicing
Cellular Component
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005687 U4 snRNP
GO:0005739 mitochondrion
GO:0046540 U4/U6 x U5 tri-snRNP complex
GO:0071001 U4/U6 snRNP
GO:0071011 precatalytic spliceosome
GO:0097526 spliceosomal tri-snRNP complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5zwm, PDBe:5zwm, PDBj:5zwm
PDBsum5zwm
PubMed29794219
UniProtP49704|PRP31_YEAST Pre-mRNA-processing factor 31 (Gene Name=PRP31)

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