Structure of PDB 5z3g Chain L Binding Site BS01

Receptor Information
>5z3g Chain L (length=191) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKYIQTEQQIEVPEGVTVSIKSRIVKVVGPRGTLTKNLKHIDVTFTKVNN
QLIKVAVHNGGRKHVAALRTVKSLVDNMITGVTKGYKYKMRYVYAHFPIN
VNIVEKDGAKFIEVRNFLGDKKIRNVPVRDGVTIEFSTNVKDEIVLSGNS
VEDVSQNAADLQQICRVRNKDIRKFLDGIYVSHKGFITEDL
Ligand information
>5z3g Chain A (length=1501) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guuugaccucaaaucagguaggaguacccgcugaacuuaagcauaucaau
aagcggaggaaaagaaaccaaccgggauugccuuaguaacggcgagugaa
gcggcaaaagcucaaauuugaaaucugguaccuucggugcccgaguugua
auuuggagagggcaacuuuggggccguuccuugucuauguuccuuggaac
aggacgucauagagggugagaaucccguguggcgaggagugcgguucuuu
guaaagugccuucgaagagucgaguuguuugggaaugcagcucuaagugg
guggccaucuaaagcuaaauauuggcgagagaccgauagcgaacaaguac
agugauggaaagaugaaaagaacuuugaaaagagagugaaaaaguacgug
aaauuguugaaagggaagggcauuugaucagacaugguguuuugugcccu
cugcuccuuguggguaggggacgcauuucacugggccagcaucaguuuug
guggcaggauaaauccauaggaauguagcuugccucgguaaguauuauag
ccugugggaauacugccagcugggacugaggacugcgacguaagucaagg
augcuggcauaaugguuauaugccgcccgucuugaaacacggaccaagga
gucuaacgucuaugcgaguguuuggguguaaaacccauacgcguaagguu
ggggccucgcaagaggugcacaaucgaccgauccggauuugaguaagagc
auagcuguugggacccgaaagauggugaccaucuaguagcugguuccugc
cgaaguuucccucaggauagcagaagcucguaucaguuuuaugguaagga
augaagagcuuuuagugggccauuuuuggagaacuggcgaugcgggauga
accgaacguagaguuaaggugccggaauacacgcucacaaaagguguuag
uucaucugaacuagcccugggcgcucaagcguguuaccuauacucuaccg
ucaggguugauaugaugcccugacgaguaggcaggcguggaggucaguga
cgaagccuagaccguaaggucgggucgaacggccucuagugcagaucuug
gugguaguagcuagaucuagcgaaaccacagccaaggcuuggguuaccgc
aauaguaauugaacuuaguacgagaggaacaguucauucggauaauuggu
uuuugcggcugucugaucaggcauugccgcgaagcuaccauccgcuggau
uauggcugaacgccucuaagucagaauccaugcuagaacgcggugaugcu
ccacacaaagauggauacgaauaaggcguccuuguggcgucgcugaacca
uagcaggcuagcaacggugcacuuggcggaaaggccuugggugcuugcug
gcgaauugcaaugucagcguggggauaaaucauuuguauacgacuuagau
guacaacgggguauuguaagcgcugagauuaagccuuuguugucugauuu
g
..........................<<<<<<.....<......>.....
.>>>>>.>.........<<....>>..<<<<<......<<.....>>...
..>>>>>..<<<..<........<<.<<<<<<...>>>>>>.>>......
..>....<<<<<<.<<<<<<<<<<<<<<<<<<<<<.....<<<<......
>>>>.(.......<<<......)>>>....>>>>>>>>..>>>>>>>>..
..>>>>>>>>>>>........<<<<<<<........>>>>>>>.....<<
<<<..>>>>>..>>>..................................<
<....>>...............<<<......>>>................
..................<<<<<.<<<<<<.....<<<<...<<<..<<<
<<<<<.......>>>>>>>>..>>>...>>>>..<<<<<<<.<<<<<<<<
<<<<<<<.....<<<<<<<<<......<<<<<<....>>>>>>.......
>>>>>>>.>.>.>>>>>.>>>>>>>>>>........<<<....>>>....
.>>>>>>>....>>>>>>.>>>>>..<<<<........>>>><<<<<<..
...<<<<<.<<<<<<..<<<...<<<<.....>>>>...>>>....<<<<
<..<<<<<....>>>>>...>>>>>.<<....<..>......>>....>>
>>>>.>>>>>...<<.<...<<<<<<.>>>>>>......>.>>..<<<<<
<......<<<....>>>..<<<<<<<<.....<<<.<<<<<<.>>>>..>
>>>>...>>>>>>.>>..<<<<.<<<....>>>.>>>>....<<<.....
.>>>...<<<<<<<..<<<<(((.....<<<<<<.......<<<.<<<<<
<<<<..>>>>>>>>>>>>.)))......>>>>>>.>>>>..>>>>>>><<
<<<<<<<.........>>>>>>>>>....>>>>>><<<<<<<<<<.<<..
....<<<<.<<<<....>>>>>>>>...>>>>>>>>>>.>>.....>>>>
>><<.....<<<<<..>>>>>....>>....<<<<<.>>>>>.<<<<<<<
..<<<<...<<<<<<...............>>>>>>..<<<<<...<<<<
....<<<<<<<<<......>>>>..>>>>>...>>>>..>>>>>.<<<<.
..<<<<<...........>>>>>...>>>>.>>>>....>>>>>>>..<<
<<<<........<<..........<<<<<<.....>>>>>>......>>.
......<<<<<<...<<<<<.<..<<<......>>>..>.>>>>>.>>>>
>>................>>>>>>.<<<<<<.<..<.......>..>...
..<<<<<.<<<.<<.....<..>....>>....>>>..>>>>>..>>>>>
>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5z3g Cryo-EM structure of an early precursor of large ribosomal subunit reveals a half-assembled intermediate.
Resolution3.65 Å
Binding residue
(original residue number in PDB)		M1 S19 I20 K21 S22 R23 K26 K39 H40 V43 T44 H58 R62 A66 R69 T70 S73 N77 H96 F97 D120 K121 K122 V151 E152 S155 Q156 A159 D160 Q163 K174 F175
Binding residue
(residue number reindexed from 1)		M1 S19 I20 K21 S22 R23 K26 K39 H40 V43 T44 H58 R62 A66 R69 T70 S73 N77 H96 F97 D120 K121 K122 V151 E152 S155 Q156 A159 D160 Q163 K174 F175
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5z3g, PDBe:5z3g, PDBj:5z3g
PDBsum5z3g
PubMed29557065
UniProtP05738|RL9A_YEAST Large ribosomal subunit protein uL6A (Gene Name=RPL9A)

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