Structure of PDB 5xxu Chain L Binding Site BS01 |
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| >5xxu Chain 2 (length=1619)
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aaccugguugauccugccaguagucauaugcuugucuuaaagauuaagcc
augcaugucuaaguauaagcuuuuauacggcuaaacugcgaauggcucau
uaaaacaguuauaguuuauuugauggucuacauggauaaccgugguaauu
cuauggcuaauaccugcgcacaguguuuauuagauacagaaccaagguga
uucauaguaaccgaacggaucgcgcugcgacggaucauucaaguuucuga
ccuaucagcuuucgacgguacuguaauggacuaccguggcagugacgggu
aacggggaauuaggguucgauuccggagagggagccugagaaacggcuac
cacaucuaaggaaggcagcaggcgcgcaaauuacccaauccugauucagg
gagguagugacaagaaauaacaaccuggagugauuggaugauaggaaucc
aaaccccuuucagaguaacaauuggagggcaagucuggugccagcagccg
cgguaauuccagcuccaauagcguauauuaaaguuguugcaguuaaaaag
cucguaguuggauuucugcuggaaggccaauucuagcauccuucuggacu
uuuacuuugagaaaauuagaguguuucaagcaggcuugucgccuugaaua
cucagcauggaauaauaagauuucggcccuauuuugguuucuaggacuga
aguaaugauuaauagggacgguugggggcauucguauuuaacugucagag
gugaaauucuuagauuuguuaaagacgaacuacugcgaaagcauuugcca
aagauguuuucauuaaucaagaacgaaaguuaggggcucgaagacgauca
gauaccgucguagucuuaaccauaaacuaugccgacuagagauaggaaaa
cgucaugacuucuccugcaccuuaugagaaaccaaagucuuuggguucug
gggggaguauggucgcaaggcugaaacuuaaaggaauugacggaagggca
ccaccaggcguggagccugcggcuuaauuugacucaacacggggaaacuc
accagguccagacauaggaauugacagauugauagcucuuucuugauucu
augggugguggugcauggccguucuuaguugguggagugauuugucuggu
uaauuccguuaacgaacgagaccuuaaccugcuaaauaggaucaggaacu
ucguguucuuguaucacuucuuagagggacuuugcgugucuaacgcaagg
aaguuugaggcaauaacaggucugugaugcccuuagauguucugggcugc
acgcgcgcuacacugaugcauccaacgaguccuuggccgauaggucuagg
uaaucuugugaguaugcaucgugauggggauagauuauugcaauuauuaa
ucuucaacgaggaaugccuaguaggcgcaagucagcacguugcgccgauu
acgucccugcccuuuguacacaccgcccgucgcuccuaccgauugagugu
uccggugaauuauucggaccguuuuguggcccgaaaugggaaguuuugug
aaccuuaacacuuagaggaaggagaagucguaacaagguuuccguaggug
aaccugcggaaggaucauu |
...<<<<<.{.[[[[>>>>><<<..<<<<<<...<<<<..<......<<<
.<<<..<<....<<....<<<.......>>>...>>.>>......<<..<
.....<<<..<<..<<....<<<<.........<.....<<<<<<.....
>>>>>>......>.........<<..<<<<<<.......(((((......
....>>>>>>....>>...<<<<...>>>>...>>>>...>>>>..>>>.
<<<....<<<....<<<<<<...........>>>>>>>>>......>>>.
..<<<.<<<<....>>>>....>>>>>>.<<.<<<..........>>>.>
>.<.<<....>>.>...>>>>>>.........<<<....<<<.....>>>
..>>>..>...>>>>.....<<<.<....>...>>>.....<.<<<....
.......>>>.>.........<<<<<((....<.<<<<.....<<..))>
>.......>>>>>>>>>>..>>>>>>.>>>.........<<<[[.....<
.<<...<<<.<<.....<<<<<<<......>>>>>>>.....<...>...
.<<<<<.<<.......<<...<.......>..<<<.....>>>.....>>
.....>>.>>..>>>.....<<<<<<.<<<....)))))...>>>.>>>>
>>......>>....<<<<<<.<<...<<<<..<<..<<<<<<.<...<<<
......>>>......>.>>>>>.>.>>.......<<....>>...>>>>.
..>>>>>.>>>...>>>...>>.>....<<<<<<<...<...<<<<.<..
...>.>>>>...>>>>>>>>..........<<<.<<.<<.<.<<<<<.<<
.<<<..>>>>>.>>>>>..>>>...<...]].>...>>.....>>>.>>>
.<<<......<<<<....>>>>....>>>..]]]].}<<<<<.<<<<<<<
..<<.<<<<<<..<<<.<<<<<<......<<........>>.........
.<<<<<.<....<<<<<......<..<<........>>..>.......>>
>>>...<<.<<<..<<.<<<<<<....<<<.<<<<......>>...<<<.
.....>>>...>>.>>>....<<<<<.<<..<<<<..<<....<<<<<<.
....>>>>>>......>>..>>>>.>>....<<<<<<.....>>>>>.>.
.....>>>>>....>>>.>>>.....>>>>>>>.....>.>>>>>...>>
.>>>>.>>>.....<<<<<<<......<<.<<<.<<<<....>>>>.>>>
....>>.......>>>>>>>...........<<<<<<..........>>>
>>>..........>>>>>>....<<<<<<<.........>>>>>>>....
..>>...>>>>>>>>>>.>>....<..<<.<.<<<<<.<<....<<<<<<
<..<<<..<<.<..<...<<<<<<<<.....>>>>>>>>...>..>.>>.
.>>>..>>>>>>>...>>.>>>>>..>.>>...>.....<<<<<<<<<<.
.>>>>>>>>>>........ |
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| PDB | 5xxu Cryo-EM structures of the 80S ribosomes from human parasites Trichomonas vaginalis and Toxoplasma gondii |
| Resolution | 3.35 Å |
Binding residue
(original residue number in PDB) | E9 A11 Q13 D16 S19 S20 Y36 D39 V40 G41 L42 R48 K59 N65 S67 I68 R69 R71 K81 M82 K83 R90 Y92 H94 P97 K98 Y99 K104 R105 H106 N108 Q130 P133 L134 S135 K136 T137 R139 F140 K156 R159 F161 |
Binding residue
(residue number reindexed from 1) | E4 A6 Q8 D11 S14 S15 Y22 D25 V26 G27 L28 R34 K45 N51 S53 I54 R55 R57 K67 M68 K69 R76 Y78 H80 P83 K84 Y85 K90 R91 H92 N94 Q116 P119 L120 S121 K122 T123 R125 F126 K142 R145 F147 |
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| Enzyme Commision number |
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