Structure of PDB 5vzy Chain L Binding Site BS01
Receptor Information
>5vzy Chain L (length=218) Species:
9606
(Homo sapiens) [
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DIVMTQSPLSLPVTPGEPASISCRSSQSLVYSNGDTYLHWYLQKPGQSPQ
LLIYKVSNRFSGVPDRFSGSGSGTDFTLKISRVEAEDVGVYYCSQSTHVP
WTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAK
VQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACE
VTHQGLSSPVTKSFNRGE
Ligand information
>5vzy Chain A (length=12) Species:
9606
(Homo sapiens) [
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HHQKLVFFAEDV
Receptor-Ligand Complex Structure
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PDB
5vzy
Structure of Crenezumab Complex with Abeta Shows Loss of beta-Hairpin.
Resolution
2.32 Å
Binding residue
(original residue number in PDB)
Y27D Y32 H34 Y36 Y49 S91 W96
Binding residue
(residue number reindexed from 1)
Y31 Y37 H39 Y41 Y54 S96 W101
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Cellular Component
GO:0005576
extracellular region
View graph for
Cellular Component
External links
PDB
RCSB:5vzy
,
PDBe:5vzy
,
PDBj:5vzy
PDBsum
5vzy
PubMed
27996029
UniProt
Q0KKI6
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