Structure of PDB 5ool Chain L Binding Site BS01

Receptor Information
>5ool Chain L (length=115) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AIQKMTRVRVVDNSALGNSPYHRAPRCIHVYKKNGVGKVGDQILLAIKGQ
KKKALIVGHCMPGPRMTPRFDSNNVVLIEDNGNPVGTRIKTPIPTSLRKR
EGEYSKVLAIAQNFV
Ligand information
>5ool Chain A (length=1441) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcuaaaccuagccccaaacccccaccuuacuaccaaaccuuagccaaacc
auuuacauaaaguauaggcgauagaaauugggcgcaauagauauaguacc
gcaagggaaagaugaaaaaaccaagcauaauauagcaaggacuaaccccu
auaccuucugcauaaugaauuaacuagaaauaacuuugcaaggagagcca
aagcuaagacccccgaaaccagacgagcuaccuaagaacagcuaagagca
cacccgucuauguagcaaaauagugggaagauuuauagguagaggcgaca
aaccuaccgagccuggugauagcugguuguccaagauagaaucuuaguuc
aacuuuaaauuugcccacagaaccaaauccccuuguaaauuuaacuguua
guccaaagaggaacagcucuuuggacacuaggaaaaaaccuuguagagag
aguaaaaaauuuaacacccauaguaggccuaaaagcagccaccaauuaag
aaagcguucaagcucaacacaaaaaucccaaacauauaacugaacuccuc
acacccaauuggaccaaucuaucacccuauagaagaacuaauguuaguau
aaguaacaugaaaacauucuccuccgcauaagccugcgucagcaacugac
aauuaacagcccaauaucuacaaucaaccaacaagucauuauuacccuca
cugucaacccaacacaggcaugcucauaaggaaagguuaaaaaaaguaaa
aggaacucggcaaaucuuaccccgccuguuuaccaaaaacaucaccucua
gcaucaccaguauuagaggcaccgccugcccagugacacauguuuaacgg
ccgcaaagguagcauaaucacuuguuccuuaaauagggaccuguaugaau
ggcuccacgaggguucagcugucucuuacuuuuaaccagugaaauugacc
ugcccgugaagaggcgggcauaacacagcaagacgagaagacccuaugga
gcuuuaauuuauuaaugcaaacaccugcauuaaaaauuucgguuggggcg
accucggagcagaacccaaccuccgagcaguacaugcuaagacuucacca
gucaaagcgaaccucaauugauccaauaacuugaccaacggaacaaguua
cccuagggauaacagcgcaauccuauucuagaguccauaucaacaauagg
guuuacgaccucgauguuggaucaggacaucccgauggugcagccgcuau
uaaagguucguuuguucaacgauuaaaguccuacgugaucugaguucaga
ccggaguaauccaggucgguuucuaucuacuuuauuccucccuguacgaa
aggacaagagaaauaaggccuacuucacaaagcgccuucccccguaaaug
auaucaucucaacuuagauacccacacccaagaacaggguu
<<<.......<<<<...............................<....
..>...........<<.....>>.......>>.>>.............<<
....>>.................>>>...........<<<.......>>>
...<.<........>.>.<<<<<<.........<<<.<<..<<....>>.
..>>.>>>...<<.<...<<<<.<.....<<<<<.<<<..<<<...>>>.
..<<<..<<<<........>>>>.>>>....>>>.>>>>>...<<.....
..>>......>.>>>>......>.>>..<<<<<<....<<<<....>>>>
<<<.<<<<<<<<<<.....<<......>>.....>>>>>>>>>>..>>>.
<<<<<<<<<<......>>>>>>>>>>...<<<......>>>....<<<.<
<<...<..............<....<<<.........>>>....>.....
..<<<......>>>..........................>...>>>>>>
........>>>>>>...<<<<<......>>>>>.........>>>>>><.
.....<<..<<<....>>><<<<..<<<<........<<<<<...>>>>>
......<<<...<<<<.......................>>>>.......
>>>.....<<......>>.>>>>.....>>>>..<<<<...<<<<<<<<.
<<.........<......<<<<<<..<<<.........>>>...<<<<<<
.............>>>>>>....<<<.<<<..<<<<<....>>>..>>>>
>..........<...........<<<<<<.....>>>>>>.....>....
>>>....>>.>>>>.....>..>>.>>>>>>>>>>>>.>>.....>....
.<<<<<........>>>>>.......<<..<<<.<<......<<<<.<<<
<<<..<<<<<.<<<<<<<<......>>>>>>>>>>>>>..<<<<.....>
>>><<<<<<...........>>>>>>..<<.....<<<..<<<<.....>
>>>..>>>....>>.........<<<....>>>............>>>>.
.>>>>>>.......<<<..<.<<<<<<...<<.......>>...>>>>>>
...>.>>.>.......<<<<<.<<<<<<..<<.<<<<<<......>>>>>
>...>>.<<<<<.....>>>>>.....>>>>>..>...>>>.>>....<<
<<<<<....>>>.>>>>....>>..>>>.>>..<<<.<<<..........
.......>>>.>>><<<<<...<<<....>>>.>>>>>......<<<...
.............>>>.........<<<<.......>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5ool Structures of the human mitochondrial ribosome in native states of assembly.
Resolution3.06 Å
Binding residue
(original residue number in PDB)		Q33 K34 M35 T36 R37 H52 R53 I58 H59 Y61 K63 N64 L74 G79 K81 C90 M91 P92 R95 E131
Binding residue
(residue number reindexed from 1)		Q3 K4 M5 T6 R7 H22 R23 I28 H29 Y31 K33 N34 L44 G49 K51 C60 M61 P62 R65 E101
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5ool, PDBe:5ool, PDBj:5ool
PDBsum5ool
PubMed28892042
UniProtQ6P1L8|RM14_HUMAN Large ribosomal subunit protein uL14m (Gene Name=MRPL14)

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