Structure of PDB 5lf0 Chain L Binding Site BS01

Receptor Information
>5lf0 Chain L (length=213) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RFSPYVFNGGTILAIAGEDFAIVASDTRLSEGFSIHTRDSPKCYKLTDKT
VIGCSGFHGDCLTLTKIIEARLKMYKHSNNKAMTTGAIAAMLSTILYSRR
FFPYYVYNIIGGLDEEGKGAVYSFDPVGSYQRDSFKAGGSASAMLQPLLD
NQVGFKNMQNVEHVPLSLDRAMRLVKDVFISAAERDVYTGDALRICIVTK
EGIREETVSLRKD
Ligand information
Receptor-Ligand Complex Structure
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PDB5lf0 The inhibition mechanism of human 20S proteasomes enables next-generation inhibitor design.
Resolution2.41 Å
Binding residue
(original residue number in PDB)		D125 P126
Binding residue
(residue number reindexed from 1)		D125 P126
Enzymatic activity
Enzyme Commision number 3.4.25.1: proteasome endopeptidase complex.
Gene Ontology
Biological Process
GO:0051603 proteolysis involved in protein catabolic process
Cellular Component
GO:0005839 proteasome core complex

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Biological Process
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Cellular Component
External links
PDB RCSB:5lf0, PDBe:5lf0, PDBj:5lf0
PDBsum5lf0
PubMed27493187
UniProtP20618|PSB1_HUMAN Proteasome subunit beta type-1 (Gene Name=PSMB1)

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