Structure of PDB 5k0y Chain L Binding Site BS01

Receptor Information
>5k0y Chain L (length=137) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PEKFQHILRVLNTNIDGRRKIAFAITAIKGVGRRYAHVVLRKADIDLTKR
AGELTEDEVERVITIMQNPRQYKIPDWFLNRQKDVKDGKYSQVLANGLDN
KLREDLERLKKIRAHRGLRHFWGLRVRGQHTKTTGRR
Ligand information
>5k0y Chain A (length=1776) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauccugccaguagcauaugcuugucucaaagauuaagcca
ugcaugucuaaguacgcacggccgguacagugaaacugcgaauggcucau
uaaaucaguuaugguuccuuuggucgcucgcuccucuccuacuuggauaa
cugugguaauucuagagcuaauacaugccgacggcgcugacucccuuugu
gugggaugcgugcauuuaucagaucaaaaccaacccggucagcggcggcg
gcuuuggugacucuagauaaccucgggccgaucgcagcccuccguggcgg
cgacgacccauucgaacgucugcccuaucaacuuucgaugguagucgccg
ugccuaccauggugaccacgggugacggggaaucaggguucgauuccgga
gagggagccugagaaacggcuaccacauccaaggaaggcagcaggcgcgc
aaauuacccacucccgacccggggagguagugacgaaaaauaacaauaca
ggacucuuucgaggcccuguaauuggaaugaguccacuuuaaauccuuua
acgaggauccauuggagggcaagucuggucgcagcagccgcgguaauucc
agcuccaauagcguauauuaaaguugcugcaguuaaaaagcucguaguug
gaucuugagggcccgccccucggcgcccccucgaugugucccgcggggcc
cgaagcguuuacuuugaaaaaauuagaguguucaaagcaggcccgagccg
ccuggauaccgcagcuaggaauaauggaauaggaccgcgguucuauuuug
uugguuuucggaacugaggccaugauuaagagggacggccgggggcauuc
guauugcgccgcuagaggugaaauucuuggaccggcgcaagacggaccag
agcgaaagcauuugccaagaauguuuucauuaaucaagaacgaaagucgg
agguucgaagacgaucagauaccgucguaguuccgaccauaaacgaugcc
gacuggcgaugcggcggcguuauucccaugacccgccgggcagcuuccgg
gaaaccaaagucuuuggguuccggggggaguaugguugcaaagcugaaac
uuaaaggaauugacggaagggcaccaccaggaguggagccugcggcuuaa
uuugacucaacacgggaaaccucacccggcccggacacggacaggauuga
cagauugauagcucuuucucgauucugugggugguggugcauggccguuc
uuaguugguggagcgauuugucugguuaauuccgauaacgaacgagacuc
uggcaugcuaacuaguuacgcgacccccgagcggucggcgucccccaacu
ucuuagagggacaaguggcguucagccacccgagauugagcaauaacagg
ucugugaugcccuuagaugucggggcugcacgcgcgcuacacugacuggc
ucagcgugugccuacccuacgccggcaggcgcggguaacccguugaaccc
cauucgugauggggaucggggauugcaauuauuccccaugaacgaggaau
ucccaguaagugcgggucauaagcuugcguugauuaagucccugcccuuu
guacacaccgcccgucgcuacuaccgauuggaugguuuagugaggcccuc
ggaucggcccgccggggucggcccacggcccuggcggagcgcugagaaga
cggucgaacuugacuaucuagaggaaguaaaagucguaacaagguuuccg
uaggugaaccugcggaaggaucauua
...<<<<<...[[[[>>>>>[[[.((((((.....{{.........[[[.
[[[..<<....<<....<<..........>>...>>.>>......{{...
.....[[[......{{....[[[....................<<.....
<<.<<<.....>>>.>>......>>..........<<...<<.<......
>.>>...>>..[[..(((((.....<<<<<<<<<<<<.<........>>>
>..............)))))......]]...<<<<.<<<......>>>.>
>>>....]]]...}}....]]].<<<....<<<....<<<<<<<......
...>>>>>>>>>>......>>>...<<<.<<<<....>>>>....>>>.}
}.<<.<<<..........>>>.>>.<.<<....>>.>...]]]]]]....
.....<<<....<<<.....>>>..>>>......}}.......<<<<<<<
<<.<<<....>>>.>>.>>>>.>>>......<<..<...........>..
>>.........<<<<<((......<<<<.....<<..))>>.......>>
>>.>>>>>..)))))).]]]............{{.......{{...[[[.
[[......<<.>>...........<<<<<...............>>>>>.
........<<<<<..<.......<<...<.......>.<<<<.......>
>>>...>>......>..>>..>>>.......[[....(((((((.....>
>>>>>>>>.)))))))...]]....]]....<<<<<<..<...<<<<..<
<..<<<<<<<<...<<<......>>>......>>>>>>>>..>>......
.<<....>>...>>>>..>..>>>.>>>...]]]...}}......<<<<<
<<...<...<<<<.<.....>.>>>>...>>>>>>>>..........<<<
.<<.<<<..<.<<<<<<.<<<<......>>>>>>>>>>.>..>>>...<<
..}}>>...>>.....>>>.....<<<......<<<<....>>>>....>
>>..]]]]..<<<<<.<<<<<<<..<<..<<<<<..<<<.<<<<<<....
..<<........>>..........<<<<<......<<<<<<.......<<
.<<<........>>>.>>.....>>>>>>.<.<<.<<<..<<<<<<<<<.
...<<<.<<<<......>>...<<<......>>>...>>.>>>....<<<
...<...<<<<..<<<<....<<<..<<<<....>>>>.>>>....>>>>
..>>>>..>.....<<<<<.....>>>>>........>>>....>>>.>>
>...>.>>>>>>>>.....>>>>>...>>.>>>>.>>>.....<<.<<<.
.......<.......<<<.<<<<....>>>>.>>>....>.........>
>>.>>............<<<<<..........>>>>>...........>>
>>>.....<<<<<<<<.......>>>>>>>>......>>...>>>>>>>>
>>.>>....<..<<.<..<<<<.<<....<<<<<<<<.<<<..<<<<.<<
...<<<<<.<<<<<<<<...........>>>>>>>.>...>>>>>...>>
.>>>>..>>>.>>>>>>>>...>>.>>>>...>.>>...>.....<<<<<
<<<<....>>>>>>>>>.........
Receptor-Ligand Complex Structure
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PDB5k0y eIF3 Peripheral Subunits Rearrangement after mRNA Binding and Start-Codon Recognition.
Resolution5.8 Å
Binding residue
(original residue number in PDB)
R23 R24 K25 F28 G35 V36 G37 R38 Y40 T53 R55 W82 F83 L84 N85 R86 Q87 K88 L103 L107 D110 H120 R121 H125 L129 R130 V131 R132 G133 Q134 H135 T136 K137 T138 T139 G140 R141 R142
Binding residue
(residue number reindexed from 1)
R18 R19 K20 F23 G30 V31 G32 R33 Y35 T48 R50 W77 F78 L79 N80 R81 Q82 K83 L98 L102 D105 H115 R116 H120 L124 R125 V126 R127 G128 Q129 H130 T131 K132 T133 T134 G135 R136 R137
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022626 cytosolic ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

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Biological Process

View graph for
Cellular Component
External links
PDB RCSB:5k0y, PDBe:5k0y, PDBj:5k0y
PDBsum5k0y
PubMed27373335
UniProtG1TPG3|RS18_RABIT Small ribosomal subunit protein uS13 (Gene Name=RPS18)

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