Structure of PDB 5d7s Chain L Binding Site BS01

Receptor Information
>5d7s Chain L (length=205) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ELTQPPSVSVAPGQTARISCSGDSIGKKYAYWYQQKPGQAPVLVIYKKRP
SGIPERFSGSNSGNTATLTISGTQAEDEADYYCSAWGDKGMVFGGGTKLT
VLGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSP
VKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEK
TVAPT
Ligand information
Ligand IDBUD
InChIInChI=1S/C4H10O2/c1-3(5)4(2)6/h3-6H,1-2H3/t3-,4-/m0/s1
InChIKeyOWBTYPJTUOEWEK-IMJSIDKUSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.0C[C@@H]([C@H](C)O)O
CACTVS 3.370C[C@H](O)[C@H](C)O
ACDLabs 12.01OC(C)C(O)C
OpenEye OEToolkits 1.7.0CC(C(C)O)O
CACTVS 3.370C[CH](O)[CH](C)O
FormulaC4 H10 O2
Name(2S,3S)-butane-2,3-diol
ChEMBL
DrugBank
ZINCZINC000000901619
PDB chain5d7s Chain L Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5d7s Molecular basis of in vitro affinity maturation and functional evolution of a neutralizing anti-human GM-CSF antibody.
Resolution1.88 Å
Binding residue
(original residue number in PDB)		S112 V113 T114 L133 I134 S135
Binding residue
(residue number reindexed from 1)		S110 V111 T112 L131 I132 S133
Annotation score1
External links