Structure of PDB 5cdw Chain L Binding Site BS01
Receptor Information
>5cdw Chain L (length=98) Species:
9606
(Homo sapiens) [
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MKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGND
VQHFKVLRDGAGKYFLGVVKFNSLNELVDYHRSTSVSRNQQIFLRDIE
Ligand information
>5cdw Chain T (length=6) Species:
9606
(Homo sapiens) [
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SYVNVQ
Receptor-Ligand Complex Structure
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PDB
5cdw
Structural and biophysical investigation of the interaction of a mutant Grb2 SH2 domain (W121G) with its cognate phosphopeptide.
Resolution
2.602 Å
Binding residue
(original residue number in PDB)
R15 R34 S38 S44 H55 F56 K57 G69
Binding residue
(residue number reindexed from 1)
R13 R32 S36 S42 H53 F54 K55 G67
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5cdw
,
PDBe:5cdw
,
PDBj:5cdw
PDBsum
5cdw
PubMed
26645482
UniProt
P62993
|GRB2_HUMAN Growth factor receptor-bound protein 2 (Gene Name=GRB2)
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