Structure of PDB 4v94 Chain L Binding Site BS01

Receptor Information
>4v94 Chain L (length=523) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PSNATFKNKEKPQEVRKANIIAARSVADAIRTSLGPKGMDKMIKTSRGEI
IISNDGHTILKQMAILHPVARMLVEVSAAQDSEAGDGTTSVVILTGALLG
AAERLLNKGIHPTIIADSFQSAAKRSVDILLEMCHKVSLSDREQLVRAAS
TSLSSKIVSQYSSFLAPLAVDSVLKISDENSKNVDLNDIRLVKKVGGTID
DTEMIDGVVLTQTAIKSAGGPTRKEKAKIGLIQFQISPPKPDTENNIIVN
DYRQMDKILKEERAYLLNICKKIKKAKCNVLLIQKSILRDAVNDLALHFL
SKLNIMVVKDIEREEIEFLSKGLGCKPIADIELFTEDRLDSADLVEEIDS
DGSKIVRVTGIRNNNARPTVSVVIRGANNMIIDETERSLHDALCVIRCLV
KERGLIAGGGAPEIEISRRLSKEARSMEGVQAFIWQEFASALEVIPTTLA
ENAGLNSIKVVTELRSKHENGELNDGISVRRSGTTNTYEEHILQPVLVST
SAITLASECVKSILRIDDIAFSR
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain4v94 Chain L Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4v94 The Molecular Architecture of the Eukaryotic Chaperonin TRiC/CCT.
Resolution3.8 Å
Binding residue
(original residue number in PDB)		D91 S157
Binding residue
(residue number reindexed from 1)		D86 S152
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) D60 T93 T94 D396
Catalytic site (residue number reindexed from 1) D55 T88 T89 D391
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0051082 unfolded protein binding
GO:0140662 ATP-dependent protein folding chaperone
Biological Process
GO:0006457 protein folding
GO:0051086 chaperone mediated protein folding independent of cofactor
Cellular Component
GO:0005737 cytoplasm
GO:0005832 chaperonin-containing T-complex

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Cellular Component
External links
PDB RCSB:4v94, PDBe:4v94, PDBj:4v94
PDBsum4v94
PubMed22503819
UniProtP39078|TCPD_YEAST T-complex protein 1 subunit delta (Gene Name=CCT4)

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