Structure of PDB 4qxu Chain L Binding Site BS01

Receptor Information

>4qxu Chain L (length=219) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

DVLMTQTPLSLPVGLGDQASISCRSSQSIVHSNGNTYLEWYLQKPGQSPK
LLIYKVSNRFSGVPDRFSGSGSGTDFTLKISRVEAEDLGVYYCFQGSHAP
YTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDIN
VKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCE
ATHKTSTSPIVKSFNRNEC

Ligand information

>4qxu Chain K (length=11) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

AEPWTVRNEDL

Receptor-Ligand Complex Structure

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Structure summary

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PDB	4qxu Inhibition mechanism of membrane metalloprotease by an exosite-swiveling conformational antibody.
Resolution	2.3 Å
Binding residue (original residue number in PDB)	H31 N35 Y37 G96 Y101
Binding residue (residue number reindexed from 1)	H31 N35 Y37 G96 Y101

External links

PDB	RCSB:4qxu, PDBe:4qxu, PDBj:4qxu
PDBsum	4qxu
PubMed	25482542

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