Structure of PDB 4kze Chain L Binding Site BS01
Receptor Information
>4kze Chain L (length=215) Species:
10090
(Mus musculus) [
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SDIQMTQSPSSLSASVGDRVTITCRASQSVSSAVAWYQQKPGKAPKLLIY
SASSLYSGVPSRFSGSRSGTDFTLTISSLQPEDFATYYCQQSYSFPSTFG
QGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWK
VDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQ
GLSSPVTKSFNRGEC
Ligand information
>4kze Chain R (length=84) [
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ggacgcgaccgaaauggugaaggacggguccagugcgaaacacgcacugu
ugaguagagugugagcuccguaacuggucgcguc
.<<<<<<<<<<..<<<<...........<.<<<<<<<.....>>>>>>>.
..>..............>>>>..>.>>>>>>>>>
Receptor-Ligand Complex Structure
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PDB
4kze
A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore.
Resolution
2.404 Å
Binding residue
(original residue number in PDB)
S92 F95
Binding residue
(residue number reindexed from 1)
S92 F95
Binding affinity
PDBbind-CN
: Kd=25nM
External links
PDB
RCSB:4kze
,
PDBe:4kze
,
PDBj:4kze
PDBsum
4kze
PubMed
24952597
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