Structure of PDB 4ilm Chain L Binding Site BS01
Receptor Information
>4ilm Chain L (length=278) Species:
273057
(Saccharolobus solfataricus P2) [
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MPLIFKIGYNVIPLQDVILPTPSSKVLKYLIQSGKLIPSLKDLITSRDKY
KPIFISHLGFNQRRIFQTNKTITKGSRLSSIIAFSTQANVLSEVADEGIF
ETVYGKFHIMIESIEIVEVEKLKEEVEKHMNDNIRVRFVSPTLLSSKVLL
PPSLSERYKKIHAGYSTLPSVGLIVAYAYNVYCNLIGKKEVEVRAFKFGI
LSNALSRIIGYDLHPVTVAIGELRKARGVMGWIEFDIPDERLKRRALNYL
LTSSYLGIGRSRGIGFGEIRLEFRKIEE
Ligand information
>4ilm Chain M (length=16) [
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gcuaaucuacuauaga
.....<<<.....>>>
Receptor-Ligand Complex Structure
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PDB
4ilm
Recognition and cleavage of a nonstructured CRISPR RNA by its processing endoribonuclease Cas6.
Resolution
3.068 Å
Binding residue
(original residue number in PDB)
R47 D48 K49 Y50 K51 S148 K150 V151 L153 S158 K162 H165 G167 Y168 Y180 T220 R232 K233 A234 R235 R268 S269 R270 G271 I272
Binding residue
(residue number reindexed from 1)
R47 D48 K49 Y50 K51 S145 K147 V148 L150 S155 K159 H162 G164 Y165 Y177 T217 R224 K225 A226 R227 R260 S261 R262 G263 I264
Enzymatic activity
Enzyme Commision number
3.1.-.-
Gene Ontology
Molecular Function
GO:0003723
RNA binding
GO:0004519
endonuclease activity
GO:0016788
hydrolase activity, acting on ester bonds
Biological Process
GO:0051607
defense response to virus
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Molecular Function
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Biological Process
External links
PDB
RCSB:4ilm
,
PDBe:4ilm
,
PDBj:4ilm
PDBsum
4ilm
PubMed
23454186
UniProt
Q97WV8
|CAS6B_SACS2 CRISPR-associated endoribonuclease Cas6 2 (Gene Name=cas6b)
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